Clostridium difficile flagellin FliC: Evaluation as adjuvant and use in a mucosal vaccine against Clostridium difficile

Clostridium difficile flagella induce a pro-inflammatory response in intestinal epithelium of mice in cooperation with toxins

(2017) Jameel Batah et al.   Scientific Reports

Flagellar Hooks and Hook Protein FlgE Participate in Host Microbe Interactions at Immunological Level

(2017) Ying Shen et al.   Scientific Reports

Clostridium difficile flagella predominantly activate TLR5-linked NF-κB pathway in epithelial cells

(2016) Jameel Batah et al.   ANAEROBE

Immunogenic properties of the surface layer precursor of Clostridium difficile and vaccination assays in animal models

(2016) J.-F. Bruxelle et al.   ANAEROBE

Calculation of the ELISA’s cut-off based on the change-point analysis method for detection of Trypanosoma cruzi infection in Bolivian dogs in the absence of controls

(2016) Frédéric Lardeux et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Breakthroughs in the treatment and prevention of Clostridium difficile infection

(2016) Larry K. Kociolek et al.   Nature Reviews Gastroenterology & Hepatology

Immunogenicity and protective efficacy of recombinant Clostridium difficile flagellar protein FliC

(2016) Chandrabali Ghose et al.   Emerging Microbes & Infections

Mucosal vaccines: a paradigm shift in the development of mucosal adjuvants and delivery vehicles

(2015) Atul Srivastava et al.   APMIS

The multiple facets of FcRn in immunity

(2015) Nigel M. Stapleton et al.   IMMUNOLOGICAL REVIEWS

The Prospect for Vaccines to Prevent Clostridium difficile Infection

(2015) Chandrabali Ghose et al.   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

New Perspectives in Clostridium difficile Disease Pathogenesis

(2015) Tanya M. Monaghan   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

The role of flagella in Clostridium difficile pathogenicity

(2015) Emma Stevenson et al.   TRENDS IN MICROBIOLOGY

Indirect Toll-like receptor 5-mediated activation of conventional dendritic cells promotes the mucosal adjuvant activity of flagellin in the respiratory tract

(2015) Delphine Fougeron et al.   VACCINE

Passive and active immunization strategies against Clostridium difficile infections: State of the art

(2014) Assaf Mizrahi et al.   ANAEROBE

Deletion of Flagellin's Hypervariable Region Abrogates Antibody-Mediated Neutralization and Systemic Activation of TLR5-Dependent Immunity

(2014) C. Nempont et al.   JOURNAL OF IMMUNOLOGY

The Flagellin FliC of Clostridium difficile Is Responsible for Pleiotropic Gene Regulation during In Vivo Infection

(2014) Amira Barketi-Klai et al.   PLoS One

European Society of Clinical Microbiology and Infectious Diseases: Update of the Treatment Guidance Document for Clostridium difficile Infection

(2013) S.B. Debast et al.   CLINICAL MICROBIOLOGY AND INFECTION

Immunization Using GroEL Decreases Clostridium difficile Intestinal Colonization

(2013) Séverine Péchiné et al.   PLoS One

Interleukin 23 Production by Intestinal CD103+CD11b+ Dendritic Cells in Response to Bacterial Flagellin Enhances Mucosal Innate Immune Defense

(2012) Melissa A. Kinnebrew et al.   IMMUNITY

Clinical and economic burden of Clostridium difficile infection in Europe: a systematic review of healthcare-facility-acquired infection

(2012) P.N. Wiegand et al.   JOURNAL OF HOSPITAL INFECTION

Clostridium difficile flagellin stimulates toll-like receptor 5, and toxin B promotes flagellin-induced chemokine production via TLR5

(2012) Yusuke Yoshino et al.   LIFE SCIENCES

Structural Basis of TLR5-Flagellin Recognition and Signaling

(2012) S.-i. Yoon et al.   SCIENCE

Encapsulation of Cwp84 into pectin beads for oral vaccination against Clostridium difficile

(2011) Chiara Sandolo et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Immunization of hamsters againstClostridium difficileinfection using the Cwp84 protease as an antigen

(2011) Séverine Péchiné et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Mutagenic Analysis of the Clostridium difficile Flagellar Proteins, FliC and FliD, and Their Contribution to Virulence in Hamsters

(2011) Tanis C. Dingle et al.   INFECTION AND IMMUNITY

Reconsidering the Sporulation Characteristics of Hypervirulent Clostridium difficile BI/NAP1/027

(2011) David A. Burns et al.   PLoS One

Immunization of young African green monkeys with OprF epitope 8–OprI–type A- and B-flagellin fusion proteins promotes the production of protective antibodies against nonmucoid Pseudomonasaeruginosa

(2009) Eric T. Weimer et al.   VACCINE

A Mouse Model of Clostridium difficile–Associated Disease

(2008) Xinhua Chen et al.   GASTROENTEROLOGY

Mucosal adjuvant activity of flagellin in aged mice

(2008) John T. Bates et al.   MECHANISMS OF AGEING AND DEVELOPMENT