Computational model of interictal discharges triggered by interneurons

Dynamic, Cell-Type-Specific Roles for GABAergic Interneurons in a Mouse Model of Optogenetically Inducible Seizures

(2017) Sattar Khoshkhoo et al.   NEURON

Phase-Locked Inhibition, but Not Excitation, Underlies Hippocampal Ripple Oscillations in Awake Mice In Vivo

(2017) Jian Gan et al.   NEURON

Dynamic changes of depolarizing GABA in a computational model of epileptogenic brain: Insight for Dravet syndrome

(2016) P. Kurbatova et al.   EXPERIMENTAL NEUROLOGY

Reduced Efficacy of the KCC2 Cotransporter Promotes Epileptic Oscillations in a Subiculum Network Model

(2016) Anatoly Buchin et al.   JOURNAL OF NEUROSCIENCE

In vitro seizure like events and changes in ionic concentration

(2016) Leandro Leite Antonio et al.   JOURNAL OF NEUROSCIENCE METHODS

Computational models of epileptiform activity

(2016) Fabrice Wendling et al.   JOURNAL OF NEUROSCIENCE METHODS

Synaptic Conductances during Interictal Discharges in Pyramidal Neurons of Rat Entorhinal Cortex

(2016) Dmitry V. Amakhin et al.   Frontiers in Cellular Neuroscience

Astrocytes restrict discharge duration and neuronal sodium loads during recurrent network activity

(2015) Claudia Karus et al.   GLIA

Selective activation of parvalbumin- or somatostatin-expressing interneurons triggers epileptic seizurelike activity in mouse medial entorhinal cortex

(2015) Latefa Yekhlef et al.   JOURNAL OF NEUROPHYSIOLOGY

Electrogenic properties of the Na+/K+ ATPase control transitions between normal and pathological brain states

(2015) Giri P. Krishnan et al.   JOURNAL OF NEUROPHYSIOLOGY

Contributions of Diverse Excitatory and Inhibitory Neurons to Recurrent Network Activity in Cerebral Cortex

(2015) G. T. Neske et al.   JOURNAL OF NEUROSCIENCE

The Contribution of Raised Intraneuronal Chloride to Epileptic Network Activity

(2015) H. Alfonsa et al.   JOURNAL OF NEUROSCIENCE

KCC2 function modulates in vitro ictogenesis

(2015) Shabnam Hamidi et al.   NEUROBIOLOGY OF DISEASE

Simplest relationship between local field potential and intracellular signals in layered neural tissue

(2015) Anton V. Chizhov et al.   PHYSICAL REVIEW E

Ion dynamics during seizures

(2015) Joseph V. Raimondo et al.   Frontiers in Cellular Neuroscience

Physiological sharp wave-ripples and interictal events in vitro: what’s the difference?

(2014) Mária R. Karlócai et al.   BRAIN

Unification of Neuronal Spikes, Seizures, and Spreading Depression

(2014) Y. Wei et al.   JOURNAL OF NEUROSCIENCE

Effects of VU0240551, a novel KCC2 antagonist, and DIDS on chloride homeostasis of neocortical neurons from rats and humans

(2014) R.A. Deisz et al.   NEUROSCIENCE

Hilar Somatostatin Interneurons Contribute to Synchronized GABA Activity in an In Vitro Epilepsy Model

(2014) Sabine Grosser et al.   PLoS One

Local Impermeant Anions Establish the Neuronal Chloride Concentration

(2014) J. Glykys et al.   SCIENCE

Cortical GABAergic excitation contributes to epileptic activities around human glioma

(2014) J. Pallud et al.   Science Translational Medicine

Structure, function, and plasticity of GABA transporters

(2014) Annalisa Scimemi   Frontiers in Cellular Neuroscience

Genesis of interictal spikes in the CA1: a computational investigation

(2014) Shivakeshavan Ratnadurai-Giridharan et al.   Frontiers in Neural Circuits

Dynamics from Seconds to Hours in Hodgkin-Huxley Model with Time-Dependent Ion Concentrations and Buffer Reservoirs

(2014) Niklas Hübel et al.   PLoS Computational Biology

Conductance-based refractory density model of primary visual cortex

(2013) Anton V. Chizhov   JOURNAL OF COMPUTATIONAL NEUROSCIENCE

Electrophysiological Heterogeneity of Fast-Spiking Interneurons: Chandelier versus Basket Cells

(2013) Nadezhda V. Povysheva et al.   PLoS One

Controlling Seizure-Like Events by Perturbing Ion Concentration Dynamics with Periodic Stimulation

(2013) Jeremy A. Owen et al.   PLoS One

Interictal spikes, fast ripples and seizures in partial epilepsies - combining multi-level computational models with experimental data

(2012) Fabrice Wendling et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Seizures as imbalanced up states: excitatory and inhibitory conductances during seizure-like events

(2012) Jokūbas Žiburkus et al.   JOURNAL OF NEUROPHYSIOLOGY

A Candidate Mechanism Underlying the Variance of Interictal Spike Propagation

(2012) H. R. Sabolek et al.   JOURNAL OF NEUROSCIENCE

Ionic Dynamics Mediate Spontaneous Termination of Seizures and Postictal Depression State

(2011) G. P. Krishnan et al.   JOURNAL OF NEUROSCIENCE

Components of neuronal chloride transport in rat and human neocortex

(2011) Rudolf A. Deisz et al.   JOURNAL OF PHYSIOLOGY-LONDON

Glutamatergic pre-ictal discharges emerge at the transition to seizure in human epilepsy

(2011) Gilles Huberfeld et al.   NATURE NEUROSCIENCE

Tonic excitation or inhibition is set by GABAA conductance in hippocampal interneurons

(2011) Inseon Song et al.   Nature Communications

Distinct Mechanisms Mediate Interictal and Pre-Ictal Discharges in Human Temporal Lobe Epilepsy

(2011) Carl E. Stafstrom   Epilepsy Currents

Impact of Fast Sodium Channel Inactivation on Spike Threshold Dynamics and Synaptic Integration

(2011) Jonathan Platkiewicz et al.   PLoS Computational Biology

Efficacy of Synaptic Inhibition Depends on Multiple, Dynamically Interacting Mechanisms Implicated in Chloride Homeostasis

(2011) Nicolas Doyon et al.   PLoS Computational Biology

Sparse and powerful cortical spikes

(2010) Jason Wolfe et al.   CURRENT OPINION IN NEUROBIOLOGY

The K+-Cl−cotransporter KCC2 promotes GABAergic excitation in the mature rat hippocampus

(2010) Tero Viitanen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Synchronous GABAA-receptor-dependent potentials in limbic areas of thein-vitroisolated adult guinea pig brain

(2009) Laura Uva et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Interneuron Diversity in Layers 2–3 of Monkey Prefrontal Cortex

(2008) Aleksey V. Zaitsev et al.   CEREBRAL CORTEX

The influence of sodium and potassium dynamics on excitability, seizures, and the stability of persistent states: II. Network and glial dynamics

(2008) Ghanim Ullah et al.   JOURNAL OF COMPUTATIONAL NEUROSCIENCE

Efficient evaluation of neuron populations receiving colored-noise current based on a refractory density method

(2008) Anton V. Chizhov et al.   PHYSICAL REVIEW E