Oligomeric and fibrillar amyloid beta 42 induce platelet aggregation partially through GPVI

Pancreatic Cancer-Induced Neutrophil Extracellular Traps: A Potential Contributor to Cancer-Associated Thrombosis

(2017) Norbaini Abdol Razak et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Plasma Amyloid-β Peptides in Type 2 Diabetes: A Matched Case-Control Study

(2017) Kirsten E. Peters et al.   JOURNAL OF ALZHEIMERS DISEASE

NETosis in Alzheimer’s Disease

(2017) Enrica Caterina Pietronigro et al.   Frontiers in Immunology

Plasma Amyloid-β as a Biomarker in Alzheimer's Disease: The AIBL Study of Aging

(2017) James K. Lui et al.   JOURNAL OF ALZHEIMERS DISEASE

Increased platelet adhesion and thrombus formation in a mouse model of Alzheimer's disease

(2016) Ilaria Canobbio et al.   CELLULAR SIGNALLING

Cerebral Amyloid Angiopathy-Related Microbleeds and Cerebrospinal Fluid Biomarkers in Alzheimer’s Disease

(2016) Moeko Noguchi-Shinohara et al.   JOURNAL OF ALZHEIMERS DISEASE

β-Amyloid in CSF

(2016) Ellis S. van Etten et al.   NEUROLOGY

Platelets contribute to amyloid-β aggregation in cerebral vessels through integrin αIIbβ3–induced outside-in signaling and clusterin release

(2016) Lili Donner et al.   Science Signaling

Platelets contribute to amyloid-β aggregation in cerebral vessels through integrin αIIbβ3–induced outside-in signaling and clusterin release

(2016) Lili Donner et al.   Science Signaling

Activation of glycoprotein VI (GPVI) and C-type lectin-like receptor-2 (CLEC-2) underlies platelet activation by diesel exhaust particles and other charged/hydrophobic ligands

(2015) Osama M. Alshehri et al.   BIOCHEMICAL JOURNAL

Plasma L5 levels are elevated in ischemic stroke patients and enhance platelet aggregation

(2015) M.-Y. Shen et al.   BLOOD

Decreased Platelet APP Isoform Ratios in Autosomal Dominant Alzheimer’s Disease: Baseline Data from a DIAN Cohort Subset

(2015) Pratishtha Chatterjee et al.   Current Alzheimer Research

Platelets in the Alzheimer’s Disease Brain: do they Play a Role in Cerebral Amyloid Angiopathy?

(2015) Kathrin Kniewallner et al.   CURRENT NEUROVASCULAR RESEARCH

Migration of blood cells to β-amyloid plaques in Alzheimer's disease

(2015) Lindsay A. Hohsfield et al.   EXPERIMENTAL GERONTOLOGY

Validation and Characterization of a Novel Peptide That Binds Monomeric and Aggregated β-Amyloid and Inhibits the Formation of Neurotoxic Oligomers

(2015) Renae K. Barr et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of Glycoprotein VI Clustering by Collagen as a Mechanism of Inhibiting Collagen-Induced Platelet Responses: The Example of Losartan

(2015) Peng Jiang et al.   PLoS One

Amyloid β-peptide-dependent activation of human platelets: essential role for Ca2+and ADP in aggregation and thrombus formation

(2014) Ilaria Canobbio et al.   BIOCHEMICAL JOURNAL

Pre-activated blood platelets and a pro-thrombotic phenotype in APP23 mice modeling Alzheimer's disease

(2014) Andrea Jarre et al.   CELLULAR SIGNALLING

Association of Platelet Activation with Vascular Cognitive Impairment: Implications in Dementia Development?

(2014) Konstantinos Stellos et al.   Current Vascular Pharmacology

Amyloid β peptide stimulates platelet activation through RhoA-dependent modulation of actomyosin organization

(2014) Vijay K. Sonkar et al.   FASEB JOURNAL

Platelet-activating factors are associated with cognitive deficits in depressed coronary artery disease patients: a hypothesis-generating study

(2014) Graham Mazereeuw et al.   Journal of Neuroinflammation

Blood Platelets in the Progression of Alzheimer’s Disease

(2014) Nina S. Gowert et al.   PLoS One

Discovery of Novel GPVI Receptor Antagonists by Structure-Based Repurposing

(2014) Lewis Taylor et al.   PLoS One

Immobilized amyloid Aβ peptides support platelet adhesion and activation

(2013) Ilaria Canobbio et al.   FEBS LETTERS

Pericyte loss influences Alzheimer-like neurodegeneration in mice

(2013) Abhay P. Sagare et al.   Nature Communications

Reduced platelet amyloid precursor protein ratio (APP ratio) predicts conversion from mild cognitive impairment to Alzheimer’s disease

(2012) Isis A. Zainaghi et al.   JOURNAL OF NEURAL TRANSMISSION

Apolipoprotein E controls cerebrovascular integrity via cyclophilin A

(2012) Robert D. Bell et al.   NATURE

Association of Plasma β-Amyloid Level and Cognitive Reserve With Subsequent Cognitive Decline

(2011) Kristine Yaffe   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Coated-platelet levels and progression from mild cognitive impairment to Alzheimer disease

(2011) C. I. Prodan et al.   NEUROLOGY

Platelet interleukin-1  drives cerebrovascular inflammation

(2010) P. Thornton et al.   BLOOD

Predictive Value of Platelet Activation for the Rate of Cognitive Decline in Alzheimer's Disease Patients

(2010) Konstantinos Stellos et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Evolution of Aβ42 and Aβ40 levels and Aβ42/Aβ40 ratio in plasma during progression of Alzheimer’s disease: A multicenter assessment

(2009) K. Blennow et al.   Journal of Nutrition Health & Aging

Amyloid beta peptides in human plasma and tissues and their significance for Alzheimer's disease

(2008) Alex E. Roher et al.   Alzheimers & Dementia

Amyloid beta peptide-activated signal pathways in human platelets

(2008) Ming Y. Shen et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Differences of peripheral inflammatory markers between mild cognitive impairment and Alzheimer's disease

(2008) Paloma Bermejo et al.   IMMUNOLOGY LETTERS

Novel phage peptides attenuate beta amyloid-42 catalysed hydrogen peroxide production and associated neurotoxicity

(2008) K. Taddei et al.   NEUROBIOLOGY OF AGING

Expression of amyloid beta peptide in human platelets: Pivotal role of the phospholipase Cγ2-protein kinase C pathway in platelet activation

(2008) Ming-Yi Shen et al.   PHARMACOLOGICAL RESEARCH

Rate of progression in Alzheimer’s disease correlates with coated-platelet levels—a longitudinal study

(2008) Calin I. Prodan et al.   Translational Research