Geissoschizine synthase controls flux in the formation of monoterpenoid indole alkaloids in a Catharanthus roseus mutant

A tabersonine 3-reductase Catharanthus roseus mutant accumulates vindoline pathway intermediates

(2017) Alison Edge et al.   PLANTA

A three enzyme system to generate the Strychnos alkaloid scaffold from a central biosynthetic intermediate

(2017) Evangelos C. Tatsis et al.   Nature Communications

Discovery and metabolic engineering of iridoid/secoiridoid and monoterpenoid indole alkaloid biosynthesis

(2016) Antje M. K. Thamm et al.   PHYTOCHEMISTRY REVIEWS

Structural investigation of heteroyohimbine alkaloid synthesis reveals active site elements that control stereoselectivity

(2016) Anna Stavrinides et al.   Nature Communications

Discovery of a P450-catalyzed step in vindoline biosynthesis: a link between the aspidosperma and eburnamine alkaloids

(2015) Franziska Kellner et al.   CHEMICAL COMMUNICATIONS

Unlocking the Diversity of Alkaloids in Catharanthus roseus: Nuclear Localization Suggests Metabolic Channeling in Secondary Metabolism

(2015) Anna Stavrinides et al.   CHEMISTRY & BIOLOGY

Completion of the seven-step pathway from tabersonine to the anticancer drug precursor vindoline and its assembly in yeast

(2015) Yang Qu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

De novo production of the plant-derived alkaloid strictosidine in yeast

(2015) Stephanie Brown et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

7-Deoxyloganetic acid synthase catalyzes a key 3 step oxidation to form 7-deoxyloganetic acid in Catharanthus roseus iridoid biosynthesis

(2014) Vonny Salim et al.   PHYTOCHEMISTRY

Transcriptome analysis based on next-generation sequencing of non-model plants producing specialized metabolites of biotechnological interest

(2013) Mei Xiao et al.   JOURNAL OF BIOTECHNOLOGY

A 7-Deoxyloganetic Acid Glucosyltransferase Contributes a Key Step in Secologanin Biosynthesis in Madagascar Periwinkle

(2013) K. Asada et al.   PLANT CELL

Virus-induced gene silencing identifiesCatharanthus roseus7-deoxyloganic acid-7-hydroxylase, a step in iridoid and monoterpene indole alkaloid biosynthesis

(2013) Vonny Salim et al.   PLANT JOURNAL

Vacuolar Transport of the Medicinal Alkaloids from Catharanthus roseus Is Mediated by a Proton-Driven Antiport

(2013) I. Carqueijeiro et al.   PLANT PHYSIOLOGY

ATP-binding cassette transporter controls leaf surface secretion of anticancer drug components in Catharanthus roseus

(2013) F. Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An alternative route to cyclic terpenes by reductive cyclization in iridoid biosynthesis

(2012) Fernando Geu-Flores et al.   NATURE

Characterization of the plastidial geraniol synthase from Madagascar periwinkle which initiates the monoterpenoid branch of the alkaloid pathway in internal phloem associated parenchyma

(2012) Andrew J. Simkin et al.   PHYTOCHEMISTRY

Mining the Biodiversity of Plants: A Revolution in the Making

(2012) V. De Luca et al.   SCIENCE

Characterization and genetic linkage mapping of the horticulturally important mutation leafless inflorescence (lli) in periwinkle Catharanthus roseus

(2011) Swati Chaudhary et al.   SCIENTIA HORTICULTURAE

Synthetic biosystems for the production of high-value plant metabolites

(2011) Peter J. Facchini et al.   TRENDS IN BIOTECHNOLOGY

Screening and Identification of Many of the Compounds Present in Rauvolfia verticillata by Use of High-Pressure LC and Quadrupole TOF MS

(2010) Bo Hong et al.   CHROMATOGRAPHIA

Homolog of tocopherol C methyltransferases catalyzes N methylation in anticancer alkaloid biosynthesis

(2010) D. K. Liscombe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vinca drug components accumulate exclusively in leaf exudates of Madagascar periwinkle

(2010) J. Roepke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Leaf Epidermome of Catharanthus roseus Reveals Its Biochemical Specialization

(2008) J. Murata et al.   PLANT CELL