Review
Plant Sciences
Yutaro Shimizu, Tomohiro Uemura
Summary: Membrane trafficking is crucial for organelle maintenance and function, and the TGN plays a critical role as a sorting station. Recent studies have identified distinct subdomains of the TGN for different trafficking pathways.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Energy & Fuels
Andreas Hornung, Fabian Stenzel, Jan Grunwald
Summary: Biochar differs from charcoal in that it is a carbon-rich product obtained from the thermal decomposition of organic material in the absence of oxygen. While charcoal is traditionally made from wood, biochar can be made from a wide range of biomass and biomass residues. The production of biochar is more complex and can be tailored for specific applications, and when combined with other biofuels, it can be an economic solution to address climate change issues.
BIOMASS CONVERSION AND BIOREFINERY
(2021)
Article
Plant Sciences
Emi Ito, Tomohiro Uemura
Summary: This article mainly introduces the basic principles of membrane traffic and its diversity in plants. Through the study of regulators in the trans-Golgi network, it summarizes their functions in different transport pathways and their roles in plant development and environmental stimuli.
JOURNAL OF PLANT RESEARCH
(2022)
Article
Plant Sciences
Qijiang Cao, Wei Zhang, Xinyan Liu, Yan Li
Summary: In Arabidopsis, the AtFTCD-L protein is localized on the TGN vesicles in root cap cells and plays a role in regulating root growth and extracellular secretion of mucilage components.
Review
Plant Sciences
Alban Mariette, Hee Sung Kang, Joshua L. Heazlewood, Staffan Persson, Berit Ebert, Edwin R. Lampugnani
Summary: The growth, development, and adaptation of plants are largely influenced by the properties of their cell walls, which consist of sugars and glycosylated proteins. L-Arabinose is a key plant sugar that is widespread among plants but absent in animals. This article summarizes the processes and proteins involved in L-Arabinose synthesis, interconversion, and its role in cell wall-related functions, aiming to guide future research in this field.
PLANT AND CELL PHYSIOLOGY
(2021)
Review
Plant Sciences
Qingchen Rui, Xiaoyun Tan, Feng Liu, Yiqun Bao
Summary: In this review, we summarize the key players in Golgi maintenance demonstrated by genetic studies in plants, with an emphasis on their roles in intra-Golgi trafficking.
FRONTIERS IN PLANT SCIENCE
(2022)
Review
Biochemistry & Molecular Biology
Chiara Siniscalchi, Armando Di Palo, Aniello Russo, Nicoletta Potenza
Summary: Non-coding RNAs (ncRNAs) make up the majority of the transcriptome and participate in regulatory networks through competitive interactions, known as competing endogenous RNA (ceRNA) networks. X-inactive specific transcript (XIST) is an important long non-coding RNA (lncRNA) involved in X chromosome inactivation and is associated with miRNAs. Further research may reveal novel functions and gender-related mechanisms of XIST and other lncRNAs produced by the X-inactivation center.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Medicine, General & Internal
Eugenia Lorenzini, Alessia Ciarrocchi, Federica Torricelli
Summary: Malignant pleural mesothelioma is a clinical emergency strongly associated with asbestos exposure, with a lack of reliable markers for early identification and limited therapeutic options contributing to its high mortality rate. Recent deep profiling studies point to the epigenome as a central element in the development and progression of this cancer.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Cell Biology
Torsten W. B. Goetz, Dmytro Puchkov, Veronika Lysiuk, Janine Luetzkendorf, Alexander G. Nikonenko, Christine Quentin, Martin Lehmann, Stephan J. Sigrist, Astrid G. Petzoldt
Summary: This study demonstrates that mutations in the small GTPase Rab2 lead to accumulation of presynaptic material in the neuronal cell body, resulting in neurotransmission deficits. This abnormal assembly process is dependent on Rab2-regulated protein export and sorting at the trans-Golgi, ultimately affecting neurotransmission.
JOURNAL OF CELL BIOLOGY
(2021)
Article
Virology
Kannu Priya Pandey, Yan Zhou
Summary: The NLRP3 inflammasome is an important immune response against influenza A virus (IAV) infection. This study investigates the role of TGN dispersion and a viral protein, M2, in the activation of the NLRP3 inflammasome during IAV infection.
Editorial Material
Multidisciplinary Sciences
Brita Kilburg-Basnyat
Summary: The student stated that they don't think industry is a good fit because they are not motivated by money. As an industry scientist, this surprised me. I was attending a conference event to help graduate students and postdocs explore career options and connect with professionals from various fields. Most attendees were eager to learn about their options and some were seriously considering industry. I was glad to assist them in figuring out if it was the right path for them and how to get there. The dismissive comment from the student caught me off-guard, however, I suspect others may have felt the same way. After a brief pause, I shared my own journey.
Article
Engineering, Industrial
Helena Luegering, Dilek Tepeli, Anna Sieben
Summary: Experts believe that mass panic is not the main cause of crowd accidents, but rather an organizational issue. However, little research has been done on how lay people understand and associate with the term "mass panic". Our study found that people strongly associate the term with irrational and selfish behavior and hold both the organizers and people in the crowd responsible for such accidents.
Article
Biochemistry & Molecular Biology
Patricia Franzka, Svenja Caren Schueler, Takfarinas Kentache, Robert Storm, Andrea Bock, Istvan Katona, Joachim Weis, Katrin Buder, Christoph Kaether, Christian A. Hubner
Summary: Proteins of the secretory pathway undergo glycosylation in the ER and Golgi apparatus. Mutations in GMPPA can cause AAMR syndrome with various symptoms. Loss of GMPPA leads to Golgi fragmentation, altered protein abundance, reduced furin activity, and increased retention of alpha-DG.
Editorial Material
Cell Biology
Vojo Deretic, Daniel J. Klionsky
Summary: During the peer review process, authors may receive constructive suggestions from some reviewers and critical comments from others that need to be addressed. It is important to strike a balance between addressing reviewer comments and completing the study to ensure quality and rigor.
Article
Cell Biology
Charlotte Ford, Anup Parchure, Julia von Blume, Christopher G. Burd
Summary: The Golgi apparatus plays a key role in the synthesis and transport of glycoproteins and lipids through a series of membrane sacs called cisternae. Processed glycoproteins and lipids are packaged into transport carriers derived from the trans Golgi and trans-Golgi network (TGN) for export to different organelles. Despite remaining questions, advances have been made in understanding the molecular features of cargo clients and the sorting mechanisms within the Golgi.
JOURNAL OF CELL SCIENCE
(2021)
