Secondary metabolism of pharmaceuticals in the plant in vitro cultures: strategies, approaches, and limitations to achieving higher yield
出版年份 2017 全文链接
标题
Secondary metabolism of pharmaceuticals in the plant in vitro cultures: strategies, approaches, and limitations to achieving higher yield
作者
关键词
Medicinal plants, Plant secondary metabolism, Pharmaceuticals, Natural products, Bioactive compounds, Elicitation
出版物
PLANT CELL TISSUE AND ORGAN CULTURE
Volume 132, Issue 2, Pages 239-265
出版商
Springer Nature
发表日期
2017-11-09
DOI
10.1007/s11240-017-1332-2
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Phytocarbazoles: alkaloids with great structural diversity and pronounced biological activities
- (2017) Harald Greger PHYTOCHEMISTRY REVIEWS
- Proteome profiling reveals insights into secondary metabolism in Maytenus ilicifolia (Celastraceae) cell cultures producing quinonemethide triterpenes
- (2017) Tiago Antunes Paz et al. PLANT CELL TISSUE AND ORGAN CULTURE
- Cell line selection combined with jasmonic acid elicitation enhance camptothecin production in cell suspension cultures of Ophiorrhiza mungos L
- (2016) S. Deepthi et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Enhanced Accumulation of Scopoletin in Cell Suspension Culture of Spilanthes acmella Murr. Using Precursor Feeding
- (2016) Mohammad Abyari et al. BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY
- Use of grapevine cell cultures for the production of phytostilbenes of cosmetic interest
- (2016) Philippe Jeandet et al. COMPTES RENDUS CHIMIE
- Camptothecine production by mixed fermentation of two endophytic fungi from Nothapodytes nimmoniana
- (2016) Bhumika N. Bhalkar et al. Fungal Biology
- Natural Products as Sources of New Drugs from 1981 to 2014
- (2016) David J. Newman et al. JOURNAL OF NATURAL PRODUCTS
- Elicitation, an Effective Strategy for the Biotechnological Production of Bioactive High-Added Value Compounds in Plant Cell Factories
- (2016) Karla Ramirez-Estrada et al. MOLECULES
- Highly endoreduplicated floral organs of somaclonal variants in clonally propagated Phalaenopsis ‘Spring Dancer’
- (2016) Hyun-Jeong Lee et al. PLANT CELL TISSUE AND ORGAN CULTURE
- Enhanced plumbagin production in Plumbago indica root cultures by ʟ-alanine feeding and in situ adsorption
- (2016) Amit Jaisi et al. PLANT CELL TISSUE AND ORGAN CULTURE
- Chemical elicitors versus secondary metabolite production in vitro using plant cell, tissue and organ cultures: recent trends and a sky eye view appraisal
- (2016) Charu Chandra Giri et al. PLANT CELL TISSUE AND ORGAN CULTURE
- Renaissance in phytomedicines: promising implications of NGS technologies
- (2016) Sonal Sharma et al. PLANTA
- Production of biomass and bioactive compounds from shoot cultures of Rosa rugosa using a bioreactor culture system
- (2016) Hae-Rim Jang et al. Horticulture Environment and Biotechnology
- Establishment of embryogenic cultures and determination of their bioactive properties in Rosa rugosa
- (2016) Hye-Rim Jang et al. Horticulture Environment and Biotechnology
- Plant Metabolic Engineering Strategies for the Production of Pharmaceutical Terpenoids
- (2016) Xu Lu et al. Frontiers in Plant Science
- Micropropagation and validation of genetic and biochemical fidelity among regenerants of Nothapodytes nimmoniana (Graham) Mabb. employing ISSR markers and HPLC
- (2016) Lokesh Prakash et al. 3 Biotech
- Micropropagation and validation of genetic and biochemical fidelity among regenerants of Nothapodytes nimmoniana (Graham) Mabb. employing ISSR markers and HPLC
- (2016) Lokesh Prakash et al. 3 Biotech
- Camptothecin from Nothapodytes nimmoniana: review on biotechnology applications
- (2015) Tasiu Isah et al. ACTA PHYSIOLOGIAE PLANTARUM
- Engineering of Secondary Metabolism
- (2015) Sarah E. O'Connor Annual Review of Genetics
- Enhanced camptothecin production by ethanol addition in the suspension culture of the endophyte, Fusarium solani
- (2015) Aarthi Venugopalan et al. BIORESOURCE TECHNOLOGY
- Plants as Factories for Human Pharmaceuticals: Applications and Challenges
- (2015) Jian Yao et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Metabolic Engineering for Resveratrol Derivative Biosynthesis in Escherichia coli
- (2015) Yu Jeong Jeong et al. MOLECULES AND CELLS
- Biosynthesis and biotechnological production of anti-cancer drug Camptothecin
- (2015) Guoyin Kai et al. PHYTOCHEMISTRY REVIEWS
- Effect of plant growth regulators on the accumulation of indolizidine alkaloids in Securinega suffruticosa callus cultures
- (2015) Danuta Raj et al. PLANT CELL TISSUE AND ORGAN CULTURE
- Marked enhancement of sennoside bioactive compounds through precursor feeding in Cassia angustifolia Vahl and cloning of isochorismate synthase gene involved in its biosynthesis
- (2015) Siva K. Chetri et al. PLANT CELL TISSUE AND ORGAN CULTURE
- Effects of plant growth regulators on cell growth and alkaloids production by cell cultures of Lycopodiella inundata
- (2015) Christophe Bienaimé et al. PLANT CELL TISSUE AND ORGAN CULTURE
- Restoration of camptothecine production in attenuated endophytic fungus on re-inoculation into host plant and treatment with DNA methyltransferase inhibitor
- (2015) M. M. Vasanthakumari et al. WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
- Engineering Complex Metabolic Pathways in Plants
- (2014) Gemma Farré et al. Annual Review of Plant Biology
- Optimization of Adventitious Root Culture for Production of Biomass and Secondary Metabolites in Prunella vulgaris L.
- (2014) Hina Fazal et al. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
- A rational approach to improving the biotechnological production of taxanes in plant cell cultures of Taxus spp.
- (2014) Rosa M. Cusido et al. BIOTECHNOLOGY ADVANCES
- Bioreactors for plant cells: hardware configuration and internal environment optimization as tools for wider commercialization
- (2014) Milen I. Georgiev et al. BIOTECHNOLOGY LETTERS
- Genome sequencing and analysis of the paclitaxel-producing endophytic fungus Penicillium aurantiogriseum NRRL 62431
- (2014) Yanfang Yang et al. BMC GENOMICS
- Metabolic Activation of Pyrrolizidine Alkaloids: Insights into the Structural and Enzymatic Basis
- (2014) Jianqing Ruan et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Medicinal plant cell suspension cultures: pharmaceutical applications and high-yielding strategies for the desired secondary metabolites
- (2014) Wei Yue et al. CRITICAL REVIEWS IN BIOTECHNOLOGY
- Elicitation: A Tool for Enriching the Bioactive Composition of Foods
- (2014) Nieves Baenas et al. MOLECULES
- Production of secondary metabolites from cell and organ cultures: strategies and approaches for biomass improvement and metabolite accumulation
- (2014) Hosakatte Niranjana Murthy et al. PLANT CELL TISSUE AND ORGAN CULTURE
- In vitro propagation and camptothecin production in Nothapodytes nimmoniana
- (2014) Tasiu Isah et al. PLANT CELL TISSUE AND ORGAN CULTURE
- Changing trends in biotechnology of secondary metabolism in medicinal and aromatic plants
- (2014) Sumit G. Gandhi et al. PLANTA
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- (2014) Nikolay Vasilev et al. PLoS One
- Rethinking production of Taxol® (paclitaxel) using endophyte biotechnology
- (2014) Souvik Kusari et al. TRENDS IN BIOTECHNOLOGY
- Stable isotope-labeling studies in metabolomics: new insights into structure and dynamics of metabolic networks
- (2014) Achuthanunni Chokkathukalam et al. Bioanalysis
- Plant regeneration of Korean wild ginseng (Panax ginseng Meyer) mutant lines induced by γ-irradiation (60Co) of adventitious roots
- (2014) Jun-Ying Zhang et al. Journal of Ginseng Research
- Somatic embryo mediated mass production of Catharanthus roseus in culture vessel (bioreactor) – A comparative study
- (2014) A. Mujib et al. SAUDI JOURNAL OF BIOLOGICAL SCIENCES
- Current Approaches for Enhanced Expression of Secondary Metabolites as Bioactive Compounds in Plants for Agronomic and Human Health Purposes – a Review
- (2014) Sandra N. Jimenez-Garcia et al. POLISH JOURNAL OF FOOD AND NUTRITION SCIENCES
- Camptothecin-producing endophytic fungus Trichoderma atroviride LY357: isolation, identification, and fermentation conditions optimization for camptothecin production
- (2013) Xiang Pu et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Getting to the bottom of Taxol biosynthesis by fungi
- (2013) Uwe Heinig et al. FUNGAL DIVERSITY
- Improved production of bioactive valepotriates in whole-plant liquid cultures of Valeriana glechomifolia
- (2013) Denise Russowski et al. INDUSTRIAL CROPS AND PRODUCTS
- Prospecting for Camptothecines from Nothapodytes nimmoniana in the Western Ghats, South India: Identification of High-Yielding Sources of Camptothecin and New Families of Camptothecines
- (2013) B. T. Ramesha et al. JOURNAL OF CHROMATOGRAPHIC SCIENCE
- New plant sources of the anti-cancer alkaloid, camptothecine from the Icacinaceae taxa, India
- (2013) B.T. Ramesha et al. PHYTOMEDICINE
- Coupling Deep Transcriptome Analysis with Untargeted Metabolic Profiling in Ophiorrhiza pumila to Further the Understanding of the Biosynthesis of the Anti-Cancer Alkaloid Camptothecin and Anthraquinones
- (2013) Mami Yamazaki et al. PLANT AND CELL PHYSIOLOGY
- Network analysis for gene discovery in plant-specialized metabolism
- (2013) YASUHIRO HIGASHI et al. PLANT CELL AND ENVIRONMENT
- Enhanced production of napthoquinone metabolite (shikonin) from cell suspension culture of Arnebia sp. and its up-scaling through bioreactor
- (2013) Komal Gupta et al. 3 Biotech
- Enhanced in vitro multiplication of Nothapodytes nimmoniana Graham using semisolid and liquid cultures and estimation of camptothecin in the regenerated plants
- (2012) V. S. Dandin et al. ACTA PHYSIOLOGIAE PLANTARUM
- Chemical Ecology of Endophytic Fungi: Origins of Secondary Metabolites
- (2012) Souvik Kusari et al. CHEMISTRY & BIOLOGY
- Living between two worlds: two-phase culture systems for producing plant secondary metabolites
- (2012) Sonia Malik et al. CRITICAL REVIEWS IN BIOTECHNOLOGY
- Hairy root cultures: A suitable biological system for studying secondary metabolic pathways in plants
- (2012) Poojadevi Sharma et al. ENGINEERING IN LIFE SCIENCES
- Bioprocessing of differentiated plant in vitro systems
- (2012) Juliane Steingroewer et al. ENGINEERING IN LIFE SCIENCES
- Epigenetic Tailoring for the Production of Anti-Infective Cytosporones from the Marine Fungus Leucostoma persoonii
- (2012) Jeremy Beau et al. Marine Drugs
- Culture medium optimization for camptothecin production in cell suspension cultures of Nothapodytes nimmoniana (J. Grah.) Mabberley
- (2012) Vijai Singh Karwasara et al. Plant Biotechnology Reports
- Cellular aggregation is a key parameter associated with long term variability in paclitaxel accumulation in Taxus suspension cultures
- (2012) Rohan A. Patil et al. PLANT CELL TISSUE AND ORGAN CULTURE
- Elicitors and precursor induced effect on L-Dopa production in suspension cultures ofMucuna pruriensL.
- (2012) Sathyanarayana Raghavendra et al. Frontiers in Life Science
- An endophytic Neurospora sp. from Nothapodytes foetida producing camptothecin
- (2011) S. Rehman et al. APPLIED BIOCHEMISTRY AND MICROBIOLOGY
- Production of adventitious root biomass and secondary metabolites of Hypericum perforatum L. in a balloon type airlift reactor
- (2011) Xi-Hua Cui et al. BIORESOURCE TECHNOLOGY
- Enhanced anthocyanins and resveratrol production in Vitis vinifera cell suspension culture by indanoyl-isoleucine, N-linolenoyl-l-glutamine and insect saliva
- (2011) Zhenzhen Cai et al. ENZYME AND MICROBIAL TECHNOLOGY
- Evolution of Plant-Made Pharmaceuticals
- (2011) David R. Thomas et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Effect of Artificial Reconstitution of the Interaction between the PlantCamptotheca acuminataand the Fungal EndophyteFusarium solanion Camptothecin Biosynthesis
- (2011) Souvik Kusari et al. JOURNAL OF NATURAL PRODUCTS
- Recent advances towards development and commercialization of plant cell culture processes for the synthesis of biomolecules
- (2011) Sarah A. Wilson et al. PLANT BIOTECHNOLOGY JOURNAL
- Exudation: an expanding technique for continuous production and release of secondary metabolites from plant cell suspension and hairy root cultures
- (2011) Zhenzhen Cai et al. PLANT CELL REPORTS
- Protocols for in vitro cultures and secondary metabolite analysis of aromatic and medicinal plants
- (2010) Alison M.R. Ferrie ANNALS OF BOTANY
- Diverse Bacteria Inhabit Living Hyphae of Phylogenetically Diverse Fungal Endophytes
- (2010) M. T. Hoffman et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Establishment of cell suspension cultures of Withania somnifera for the production of withanolide A
- (2010) Praveen Nagella et al. BIORESOURCE TECHNOLOGY
- Production of adventitious roots and secondary metabolites by Hypericum perforatum L. in a bioreactor
- (2010) Xi-Hua Cui et al. BIORESOURCE TECHNOLOGY
- Long-term maintenance of in vitro cultures affects growth and secondary metabolism of St. John's Wort
- (2010) Adriana de Andrade Figueiró et al. CIENCIA RURAL
- p-Aminoacetophenonic Acids Produced by a Mangrove Endophyte Streptomyces sp. (strain HK10552)
- (2010) Fangfang Wang et al. MOLECULES
- Genotypic variation and aging effects on the embryogenic capability of Kalopanax septemlobus
- (2010) So-Young Park et al. PLANT CELL TISSUE AND ORGAN CULTURE
- Somaclonal variation in plants: causes and detection methods
- (2010) Michael W. Bairu et al. PLANT GROWTH REGULATION
- Production of the anticancer drug taxol in Taxus baccata suspension cultures: A review
- (2010) Sonia Malik et al. PROCESS BIOCHEMISTRY
- High stilbenes accumulation in root cultures of Cayratia trifolia (L.) Domin grown in shake flasks
- (2009) Jaya Arora et al. ACTA PHYSIOLOGIAE PLANTARUM
- Perfusion culture ofGlycyrrhiza inflatasuspension cells in a stir-tank bioreactor
- (2009) Guirong Wang et al. AUSTRALIAN JOURNAL OF BOTANY
- Bioreactor for cultivation of red beet hairy roots andin siturecovery of primary and secondary metabolites
- (2009) Bhagyalakshmi Neelwarne et al. ENGINEERING IN LIFE SCIENCES
- An Endophytic Fungus fromCamptotheca acuminataThat Produces Camptothecin and Analogues
- (2009) Souvik Kusari et al. JOURNAL OF NATURAL PRODUCTS
- Light-Independent Metabolomics of EndophyticThielavia subthermophilaProvides Insight into Microbial Hypericin Biosynthesis
- (2009) Souvik Kusari et al. JOURNAL OF NATURAL PRODUCTS
- Effects of sucrose and pH levels on in vitro shoot regeneration from leaf explants of Bacopa monnieri and accumulation of bacoside A in regenerated shoots
- (2009) Poornananda Madhava Naik et al. PLANT CELL TISSUE AND ORGAN CULTURE
- Establishment of adventitious root co-culture of Ginseng and Echinacea for the production of secondary metabolites
- (2008) Chun-Hua Wu et al. ACTA PHYSIOLOGIAE PLANTARUM
- Morphactin and 2iP markedly enhance accumulation of stilbenes in cell cultures of Cayratia trifolia (L.) Domin
- (2008) Chetana Roat et al. ACTA PHYSIOLOGIAE PLANTARUM
- Analysis of genetic diversity among Indian niger [Guizotia abyssinica (L. f.) Cass.] cultivars based on randomly amplified polymorphic DNA markers
- (2008) Praveen Nagella et al. ELECTRONIC JOURNAL OF BIOTECHNOLOGY
- Molecular characterization and expression analysis of a new cDNA encoding strictosidine synthase from Ophiorrhiza japonica
- (2008) Yang Lu et al. MOLECULAR BIOLOGY REPORTS
- Opium poppy and Madagascar periwinkle: model non-model systems to investigate alkaloid biosynthesis in plants
- (2008) Peter J. Facchini et al. PLANT JOURNAL
- Growth of hairy-root cultures in various bioreactors for the production of secondary metabolites
- (2007) Bhartendu Nath Mishra et al. BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY
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