4.7 Article

Pediatric Exposures to Veterinary Pharmaceuticals

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PEDIATRICS
卷 139, 期 3, 页码 -

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AMER ACAD PEDIATRICS
DOI: 10.1542/peds.2016-1496

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OBJECTIVE: To describe the epidemiology of veterinary pharmaceutical-related exposures to abstract children based on calls to a regional poison control center. METHODS: A retrospective analysis of pediatric (<= 19 years of age) exposures to pharmaceutical products intended for animal use, managed by a regional poison control center from 1999 through 2013, was conducted. Case narratives were reviewed and coded for exposure-related circumstances and intended species. Descriptive statistics were generated. RESULTS: From 1999 through 2013, the Central Ohio Poison Center received 1431 calls that related to a veterinary pharmaceutical exposure for children <= 19 years of age. Most of the pediatric calls (87.6%) involved children <= 5 years of age. Exploratory behavior was the most common exposure-related circumstance (61.4%) and ingestion accounted for the exposure route in 93% of cases. Substances commonly associated with exposures included: veterinary drugs without human equivalent (17.3%), antimicrobial agents (14.8%), and antiparasitics (14.6%). Based on substance and quantity, the majority of exposures (96.9%) were not expected to result in long-term or lasting health effects and were managed at home (94.1%). A total of 80 cases (5.6%) were referred to a health care facility, and 2 cases resulted in a moderate health effect. CONCLUSIONS: Children <= 5 years of age are most at risk for veterinary pharmaceutical- related exposures. Although most exposures do not result in a serious medical outcome, efforts to increase public awareness, appropriate product dispensing procedures, and attention to home storage practices may reduce the risk of veterinary pharmaceutical exposures to young children.

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