Pentoxifylline inhibits TLR- and inflammasome-mediated in vitro inflammatory cytokine production in human blood with greater efficacy and potency in newborns

TLR8 Senses Bacterial RNA in Human Monocytes and Plays a Nonredundant Role for Recognition ofStreptococcus pyogenes

(2015) Tatjana Eigenbrod et al.   JOURNAL OF IMMUNOLOGY

Staphylococcus epidermidisBacteremia Induces Brain Injury in Neonatal Mice via Toll-like Receptor 2-Dependent and -Independent Pathways

(2015) Dan Bi et al.   JOURNAL OF INFECTIOUS DISEASES

Pentoxifylline Therapy for Late-Onset Sepsis in Preterm Infants

(2015) Abd Elazeez Shabaan et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

TLR-2 and TLR-4 expression in monocytes of newborns with late-onset sepsis

(2014) Ana C.C. Redondo et al.   Jornal de Pediatria

Systemic Inflammation and Cerebral Palsy Risk in Extremely Preterm Infants

(2014) Karl C. K. Kuban et al.   JOURNAL OF CHILD NEUROLOGY

Time for a Neonatal-Specific Consensus Definition for Sepsis

(2014) James L. Wynn et al.   Pediatric Critical Care Medicine

Ontogeny of early life immunity

(2014) David J. Dowling et al.   TRENDS IN IMMUNOLOGY

Soluble Mediators Regulating Immunity in Early Life

(2014) Matthew Aaron Pettengill et al.   Frontiers in Immunology

Immunosuppressive CD71+ erythroid cells compromise neonatal host defence against infection

(2013) Shokrollah Elahi et al.   NATURE

The Effects of Intraperitoneal Pentoxifylline Treatment in Rat Pups With Hypoxic-Ischemic Encephalopathy

(2013) Salih Kalay et al.   PEDIATRIC NEUROLOGY

The Ultra-Potent and Selective TLR8 Agonist VTX-294 Activates Human Newborn and Adult Leukocytes

(2013) David J. Dowling et al.   PLoS One

The effects of pentoxifylline on lung inflammation in a rat model of meconium aspiration syndrome

(2012) Ali Haydar Turhan et al.   EXPERIMENTAL LUNG RESEARCH

Innate Immune Function by Toll-like Receptors: Distinct Responses in Newborns and the Elderly

(2012) Tobias R. Kollmann et al.   IMMUNITY

Imidazoquinoline Toll-like receptor 8 agonists activate human newborn monocytes and dendritic cells through adenosine-refractory and caspase-1–dependent pathways

(2012) Victoria J. Philbin et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Plasma-mediated immune suppression: a neonatal perspective

(2012) Mirjam E. Belderbos et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Innate immune activation in neonatal tracheal aspirates suggests endotoxin-driven inflammation

(2012) Katheryn E. Nathe et al.   PEDIATRIC RESEARCH

Age-Dependent Maturation of Toll-Like Receptor-Mediated Cytokine Responses in Gambian Infants

(2011) Sarah Burl et al.   PLoS One

Ontogeny of Toll-Like Receptor Mediated Cytokine Responses of Human Blood Mononuclear Cells

(2010) Nathan P. Corbett et al.   PLoS One

Pentoxifylline in Preterm Neonates

(2010) Emma Harris et al.   PEDIATRIC DRUGS

The Role of Toll-like Receptors in Perinatal Brain Injury

(2009) Carina Mallard et al.   CLINICS IN PERINATOLOGY

Cyclic AMP

(2008) Carlos H. Serezani et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY