Obesity and type 2 diabetes are associated with elevated PCSK9 levels in young women

Circulating Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Predicts Future Risk of Cardiovascular Events Independently of Established Risk FactorsCLINICAL PERSPECTIVE

(2016) Karin Leander et al.   CIRCULATION

Effect of Leptin Replacement on PCSK9 inob/obMice and Female Lipodystrophic Patients

(2016) Amy E. Levenson et al.   ENDOCRINOLOGY

Role of Insulin in the Regulation of Proprotein Convertase Subtilisin/Kexin Type 9Significance

(2015) Ji Miao et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Relationship between testosterone, estradiol and circulating PCSK9: Cross-sectional and interventional studies in humans

(2015) T.C. Ooi et al.   CLINICA CHIMICA ACTA

Positive correlation of plasma PCSK9 levels with HbA1cin patients with type 2 diabetes

(2015) Sheng-Hua Yang et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

β-Estradiol results in a proprotein convertase subtilisin/kexin type 9-dependent increase in low-density lipoprotein receptor levels in human hepatic HuH7 cells

(2015) Amanda E. Starr et al.   FEBS Journal

Plasma proprotein convertase subtilisin/kexin type 9 is associated with Lp(a) in type 2 diabetic patients

(2015) Ymène Nekaies et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

PCSK9 deficiency unmasks a sex- and tissue-specific subcellular distribution of the LDL and VLDL receptors in mice

(2015) Anna Roubtsova et al.   JOURNAL OF LIPID RESEARCH

The Effects of Estrogen on Serum Level and Hepatocyte Expression of PCSK9

(2015) Wen Guo et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Cardiovascular Disease Risk Factors in Youth With Diabetes Mellitus

(2014) David M. Maahs et al.   CIRCULATION

Influence of physiological changes in endogenous estrogen on circulating PCSK9 and LDL cholesterol

(2014) Moumita Ghosh et al.   JOURNAL OF LIPID RESEARCH

Predictors of Mortality Over 8 Years in Type 2 Diabetic Patients: Translating Research Into Action for Diabetes (TRIAD)

(2012) L. N. McEwen et al.   DIABETES CARE

Endogenous Estrogens Lower Plasma PCSK9 and LDL Cholesterol But Not Lp(a) or Bile Acid Synthesis in Women

(2011) Lena Persson et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Plasma proprotein convertase subtilisin kexin type 9 is not altered in subjects with impaired glucose metabolism and type 2 diabetes mellitus, but its relationship with non-HDL cholesterol and apolipoprotein B may be modified by type 2 diabetes mellitus: The CODAM study

(2011) M.C.G.J. Brouwers et al.   ATHEROSCLEROSIS

Lack of association between plasma PCSK9 and LDL-apoB100 catabolism in patients with uncontrolled type 2 diabetes

(2011) Bruno Vergès et al.   ATHEROSCLEROSIS

Clinical Usefulness of Different Lipid Measures for Prediction of Coronary Heart Disease in Type 2 Diabetes: A report from the Swedish National Diabetes Register

(2011) B. Eliasson et al.   DIABETES CARE

Association between plasma PCSK9 and gamma-glutamyl transferase levels in diabetic patients

(2010) Bertrand Cariou et al.   ATHEROSCLEROSIS

Serum PCSK9 is associated with multiple metabolic factors in a large Han Chinese population

(2010) Qin Cui et al.   ATHEROSCLEROSIS

Plasma proprotein convertase subtilisin–kexin type 9 does not change during 24h insulin infusion in healthy subjects and type 2 diabetic patients

(2010) Paul J.W.H. Kappelle et al.   ATHEROSCLEROSIS

The effects of obesity and type 2 diabetes mellitus on cardiac structure and function in adolescents and young adults

(2010) A. S. Shah et al.   DIABETOLOGIA

Metabolic syndrome, dyslipidemia, hypertension and type 2 diabetes in youth: from diagnosis to treatment

(2010) Alfredo Halpern et al.   Diabetology & Metabolic Syndrome

Youth With Obesity and Obesity-Related Type 2 Diabetes Mellitus Demonstrate Abnormalities in Carotid Structure and Function

(2009) Elaine M. Urbina et al.   CIRCULATION

Plasma PCSK9 Is Associated with Age, Sex, and Multiple Metabolic Markers in a Population-Based Sample of Children and Adolescents

(2009) A. Baass et al.   CLINICAL CHEMISTRY

Genetic and Metabolic Determinants of Plasma PCSK9 Levels

(2009) Susan G. Lakoski et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Importance of Proprotein Convertase Subtilisin/Kexin Type 9 in the Hormonal and Dietary Regulation of Rat Liver Low-Density Lipoprotein Receptors

(2008) Lena Persson et al.   ENDOCRINOLOGY

Plasma PCSK9 levels are significantly modified by statins and fibrates in humans

(2008) Janice Mayne et al.   Lipids in Health and Disease