Article
Engineering, Environmental
Weisen Yang, Yifei Liu, Yaqin Zhu, Wenlong Jiang, Fengshuo Shi, Jiapeng Hu, Shaohua Jiang, Shaoju Jian
Summary: In this study, two chitosan-based magnetic microspheres were successfully synthesized and used for the adsorption removal of dyes in wastewater. The results showed that these magnetic microspheres exhibited excellent adsorption performance for the dyes, and they also demonstrated good stability and recyclability.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Nethmi S. L. Dissanayake, Maadri A. A. Pathirana, Nandula D. D. Wanasekara, Boris Mahltig, Gayani K. K. Nandasiri
Summary: This study investigates a novel two-tier nanocomposite membrane, comprising a top layer of electrosprayed chitosan-graphene oxide and a bottom layer of electrospun ethylene diamine functionalized polyacrylonitrile nanofibers, for the simultaneous removal of congo red and methylene blue dyes in textile effluent.
Article
Pharmacology & Pharmacy
Linh Phuong Ta, Erika Bujna, Szilard Kun, Dimitris Charalampopoulos, Vitaliy V. Khutoryanskiy
Summary: The study focused on the importance of prolonged gastrointestinal retention for probiotics delivery. Different formulations of alginate microparticles were prepared using electrospray technique, with chitosan-coated microparticles showing the highest mucoadhesive property. A novel in vitro wash-off mucoadhesion test setup was successfully validated for evaluating the performance of these probiotic formulations.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2021)
Article
Polymer Science
Andrea Loncarevic, Karla Ostojic, Inga Urlic, Anamarija Rogina
Summary: The aim of this study was to prepare bimetallic chitosan microgels and investigate the effects of metal-ion type and content on the properties of the microgels. The microgels were produced using electrohydrodynamic atomization process, and their size and morphology were influenced by the quantity of Cu2+ ions. The bimetallic chitosan microgels showed good stability during enzymatic degradation and exhibited good cytocompatibility.
Article
Biochemistry & Molecular Biology
Jianfeng Zhou, Yelin Dai, Junhao Fu, Chao Yan, Deng-Guang Yu, Tao Yi
Summary: In the nano era, the combination of nanomaterials and macro materials can lead to the development of novel trans-scale products with improved functional performances. This study presents a brand-new hybrid material, consisting of nanofibers and microparticles, fabricated through a sequential electrohydrodynamic atomization (EHDA) process. The hybrid material demonstrated a typical topography with microparticles distributed on the nanofibers, and showed fine compatibility between the components. In vitro dissolution tests confirmed the ability of the hybrid material to provide designed dual-step drug release profiles. This work paves the way for the development of trans-scale functional materials.
Article
Cell Biology
Brian S. Ferguson, Leslie E. Neidert, Matthew J. Rogatzki, Keith R. Lohse, L. Bruce Gladden, Heidi A. Kluess
Summary: The study found no significant difference in the release of ATP from RBCs of different densities under hypoxic and normoxic conditions, and the release of ATP was linearly correlated with the release of Hb.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
(2021)
Article
Polymer Science
Esra Altun, Jubair Ahmed, Mehmet Onur Aydogdu, Anthony Harker, Mohan Edirisinghe
Summary: Polycaprolactone (PCL) is a widely used material in various applications to address global health problems. By changing key operating parameters and solution properties, PCL microparticles and fibers can be separately produced. The morphology of PCL is found to be highly dependent on solvents and operating parameters.
EUROPEAN POLYMER JOURNAL
(2022)
Article
Polymer Science
Esra Altun, Jubair Ahmed, Mehmet Onur Aydogdu, Anthony Harker, Mohan Edirisinghe
Summary: PCL microparticles and fibers were separately produced by changing key operating parameters of EHD and PG systems and PCL solution properties. The use of binary solvent systems altered particle morphologies and diameters, while increased pressure and the use of different solvents greatly affected the characteristics of resulting fibers.
EUROPEAN POLYMER JOURNAL
(2022)
Article
Pharmacology & Pharmacy
Nidhi Mishra, Surbhi Pal, Madhu Sharma, Raquibun Nisha, Ravi Raj Pal, Priya Singh, Samipta Singh, Priyanka Maurya, Neelu Singh, Prabhat Ranjan Mishra, Shubhini A. Saraf
Summary: Polysaccharide-based nanoparticles PN/CN have been used to deliver phytic acid (IP6) to the colon orally due to their solubility, biocompatibility, and suitability for drug delivery. The study prepared two sets of PEGylated NPs using blending-crosslinking of polymers followed by emulsification-solvent evaporation, and found that the PEGylated-TPP*PN-CN-NPs had time-dependent uptake in J774.2 cell lines.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2023)
Review
Polymer Science
Mallesh Kurakula, N. Raghavendra Naveen
Summary: Chitosan has been effectively utilized in biomedical applications, particularly in drug delivery, through the emerging technology of electrospraying. This technique enables successful loading and delivery of various therapeutic agents, and the review also discusses parameters, polymer types, advantages, and limitations associated with electrosprayed chitosan. The comprehensive analysis covers a range of biomedical applications and trends in patents related to electrosprayed chitosan products, highlighting the potential for commercialization and safe fabrication.
EUROPEAN POLYMER JOURNAL
(2021)
Article
Biochemistry & Molecular Biology
Jialin Song, Jinhuan Zong, Chengye Ma, Shanfeng Chen, Hongjun Li, Dongliang Zhang
Summary: The study involved chitosan coating on microparticles of corn starch and resveratrol, with the addition of alpha-amylase to improve stability and release ratio. The research showed that chitosan coating and alpha-amylase addition were effective in enhancing the properties of the microcapsules.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Polymer Science
Muhaimin Muhaimin, Anis Yohana Chaerunisaa, Roland Bodmeier
Summary: This study investigated and characterized the incorporation of propranolol HCl within ethyl cellulose microparticle blends using the solvent evaporation method. The microparticle blends were prepared with a water-in-oil-in-water (W/O/W) solvent evaporation method and contained the same drug Propranolol HCl. The morphology, particle size, encapsulation efficiency, and in vitro drug release were analyzed. The results showed that the microparticles exhibited different properties depending on the preparation conditions, and there was an interaction between the primary emulsions.
POLYMER INTERNATIONAL
(2023)
Review
Chemistry, Multidisciplinary
Thiruchelvi Pulingam, Parisa Foroozandeh, Jo-Ann Chuah, Kumar Sudesh
Summary: This review article discusses the different methods employed for the production of polymeric nanoparticles (PNPs) and their physicochemical properties influenced by experimental parameters. The tailored characteristics of PNPs can be utilized as drug carriers for targeted therapies in hospitals for point-of-care diagnostics.
Article
Thermodynamics
Paolo E. Santangelo, Marcello Romagnoli, Marco Puglia
Summary: Inkjet printing has evolved significantly and is widely used for various applications. This study presents an experimental approach to evaluate the drying kinetics and foam formation in inks used in fuel-cell manufacturing. The methods used in this study allow for the assessment of ink printability, quantitative comparison of different inks, and evaluation of commonly used additives.
EXPERIMENTAL THERMAL AND FLUID SCIENCE
(2022)
Article
Materials Science, Multidisciplinary
Azin Rashidy Ahmady, Kavoos Razmjooee, Vida Nazar, Saeed Saber-Samandari
Summary: This study compared alginate microparticles and nanoparticles as thymol delivery systems. The results showed that thymol-loaded alginate nanoparticles released thymol in a more sustainable and controllable manner, and both carriers exhibited good cell viability and antibacterial properties.
MATERIALS CHEMISTRY AND PHYSICS
(2023)
Article
Engineering, Chemical
Bingyao Wang, Tianyi Cai, Xiaoshu Cai, Wu Zhou, Zeqi Liu
Summary: The size and morphology of nanoparticles significantly impact their performance. Current methods, such as electron microscopy or atomic force microscopy, have limitations in sample preparation, processing time, and quantitative characterization. Therefore, it is crucial to develop a fast, accurate, and statistical method for measuring nanoparticle size and morphology. In this study, a new method called polarized imaging dynamic light scattering (PIDLS) is proposed, which irradiates nanoparticles with a vertical linearly polarized laser beam and utilizes a polarization camera to collect dynamic light scattering images at different polarization directions. The method effectively determines particle size, morphology, and sphericity based on depolarization patterns and degree of linear polarization. PIDLS also enables simultaneous measurement of particle size and morphology distributions, allowing for the evaluation of particle uniformity. The effectiveness of PIDLS is validated with the measurement of five types of industrial titanium dioxide.
Article
Engineering, Chemical
Qingye Meng, Shuangling Zhong, Jingfei Wang, Zhenqian Zhang, Yan Gao, Xuejun Cui
Summary: In this study, a non-toxic natural polysaccharide, sodium alginate (SA), was developed for targeted delivery of curcumin (CUR) in tumor therapy. The CUR was coated in microcapsules using a quick, efficient, and environment-friendly sonochemical method. The microcapsules showed similar toxicity to free curcumin in anti-tumour evaluation and exhibited effective antibacterial properties. This research has the potential to provide a low-cost tumor targeting vector and can be promoted for clinical application.
Article
Engineering, Chemical
Christin Velten, Mirko Ebert, Christian Lessig, Katharina Zaehringer
Summary: Ray tracing Particle Image Velocimetry (RT-PIV) is an optical technique that corrects for distortions in velocity measurements caused by transparent geometries in challenging optical systems. This study focuses on the challenges and implications of using RT-PIV in a body centred cubic (bcc) sphere packing with gaseous flow, where transparent glass balls are used for optical access. The results demonstrate the effectiveness of the method in reconstructing velocity fields behind transparent spheres.
Article
Engineering, Chemical
Yanhao Ye, Ji Xu, Wei Ge
Summary: By modeling neighboring particles as a single coarse-grained particle, the discrete particle method (DPM) can now simulate industrial-scale particle-fluid systems. However, there is still a lack of a systematic approach to determine the properties and interaction models of these coarse-grained particles, which affects the predictability of the method. In this study, kernel functions for modeling the coarse-grained particles are constructed based on the analysis of collisions between predefined particle groups, and the model parameters are determined by equating the statistical properties of the coarse-grained particles to those of the real particles. This approach has been effective in simulating the homogeneous cooling of granular gas and experimental fluidized beds.
Article
Engineering, Chemical
Boris I. Kharisov, Oxana V. Kharissova, Lucy T. Gonzalez, Yolanda Pena Mendez, Igor E. Uflyand, Idalia Gomez de la Fuente
Summary: Hydroxyapatite (HA) composites with carbon allotropes and nanocarbons are rapidly developing in materials chemistry, especially for medical applications. These composites can be synthesized using various methods and exhibit biocompatibility and hemocompatibility, making them suitable for bone regeneration and wastewater treatment.
Article
Engineering, Chemical
Xing Li, Qun Chen, Zhaozhao Liu, Cheng Zhou, Chen Wang, Chen Chen
Summary: The particle size distribution (PSD) curve is an important expression of soil properties. However, existing characteristic parameters can only represent some points of the curve and fail to capture all the information. This paper introduces a new fraction characteristic parameter based on grading entropy and proposes a refined presentation method for the PSD curve. The new method not only represents the differences in curve width more accurately but also has higher discrimination ability. The application of this method in describing deposit distribution and predicting soil hydraulic conductivity is discussed. The research results can provide reference for the refined representation of PSD curves.
Article
Engineering, Chemical
Qingjin Zhang, Liangliang Fu, Guangwen Xu, Dingrong Bai
Summary: This study comprehensively analyzes the temperature effect on the minimum fluidization velocity (Umf) in fluidized-bed reactors. The analysis reveals the influence of temperature on Umf is determined by the relative importance of hydrodynamic forces and interparticle forces, which result in changes in gas properties, bed voidage, and physiochemical characteristics of particles. An equation is derived to predict the temperature influences on Umf under broad temperature conditions.
Article
Engineering, Chemical
Josephine Oppotsch, Matthias Steinke, Miriam Fritsch, Fritz -Herbert Heinsius, Thomas Held, Nikoline Hilse, Viktor Scherer, Ulrich Wiedner
Summary: This work is the second part of a simulation study on processing densely packed and moving granular assemblies using PEPT. A cost-effective PET-like detector system is being developed to overcome the high cost of PET scanners commonly used for PEPT. Monte Carlo simulations and Geant4 software were used to study the spatial resolution of different scenarios, and it was found that oversampling and iteration improved the resolution significantly.
Article
Engineering, Chemical
Lian Duan, Zhixun Xia, Yunchao Feng, Binbin Chen, Likun Ma, Jianxin Hu
Summary: In this study, boron-magnesium agglomerates with varying mass ratios were prepared and the combustion process of these agglomerates under different oxygen-rich concentrations were investigated. The results showed that when the mass fraction of magnesium powder in boron-magnesium agglomerates exceeded a certain threshold, a transient flameout process occurred. This process is affected by the magnesium content of the agglomerate and the oxygen concentration in the ambient atmosphere.
Article
Engineering, Chemical
Lixia Hou, Chunxiao Qu, Min Su, Zhihan Liang, Qi Hao
Summary: This study investigates the impact of polymer modified Fe3O4 nanoparticles on lysozyme (Lys) crystallization under different conditions, using functionalized Fe3O4 magnetic nanoparticles (Polymer C@Fe3O4) as nucleation agents. The findings show that the surface charge density of Polymer C@Fe3O4 is highest at a modification mass ratio of 8:3 for Fe3O4 to Polymer C. By adding 15% of the PolymerC@Fe3O4 prepared from Fe3O4 with an average particle size of 150 nm, magnetic core lysozyme (M-Lys) crystals with an average particle size of 11.08 mm, narrow size distribution, and regular morphology were obtained with a yield of 82.42% within 60 min.
Article
Engineering, Chemical
Fangling Hu, Liangliang Fu, Qingjin Zhang, Guangwen Xu, Dingrong Bai
Summary: This study proposes a method for synthesizing high-quality forsterite using abundant boron mud waste through high-temperature thermochemical reactions. The reaction can be completed rapidly at low temperatures due to the high reactivity of fine raw powder materials. The synthesized forsterite products exhibit high densification, well-developed grains, and an activation energy of 165.5 kJ/mol in the temperature range of 1100-1500°C. This study provides a low-cost method for producing forsterite and an efficient solution for treating solid waste.
Article
Engineering, Chemical
Yi Liu, Yunyan Guo, Rui Zhu, Jinqiang Zhou, Zhengxu Lin, Kai Han, Chongwei An, Jingyu Wang, Bidong Wu
Summary: Improved controllability and energy density of ignition agents are important for the development of energetic composite materials. In this study, HNS/CL-20 composite microspheres were prepared using droplet microfluidics and emulsification techniques with GAP as the binder. The microspheres exhibited higher sphericity and particle size uniformity compared to raw HNS, and retained the crystal structure of both HNS and CL-20. The microspheres also showed higher apparent activation energy, better safety performance, and good dispersibility, demonstrating excellent ignition performance and significant energy release effects.
Article
Engineering, Chemical
Max Kriegeskorte, Nikoline Hilse, Phil Spatz, Viktor Scherer
Summary: This study experimentally analyzed the particle mechanics of a single floor in a multiple hearth furnace. The results showed that increasing the blade angle led to an increase in the particle free surface area. The frequency distribution of the mean distance among particles provided information about the morphology of the particle bulk.
Article
Engineering, Chemical
Min Cai, Shuangzhu Kong, Sheng Chen, Mengxi Liu, Chunxi Lu
Summary: Reasonable reactor design is crucial for increasing the C2 yield in the oxidative coupling of methane (OCM). This study focused on large-scale fluidized bed reactors and conducted experiments and simulations to investigate their hydrodynamics and reaction performance. The results showed that the consecutive reactions of ethylene were severe in the bubbling fluidized bed (BFB) reactor due to gas back-mixing, high solids holdup, and non-uniform solids distribution, while they were negligible in the riser reactor. Both reactors achieved isothermal operation for the OCM process, with the riser reactor showing higher C2 selectivity and yield compared to the BFB reactor. This study provides valuable information for OCM reactor design and commercialization.
Article
Engineering, Chemical
Jiangkui Hu, Shijie Yang, Yingying Pei, Xilong Wang, Yulong Liao, Shuai Li, Aolong Yue, Jia-Qi Huang, Hong Yuan
Summary: This review discusses the interfacial issues in all-solid-state lithium batteries (ASSLBs) based on sulfide solid electrolytes (SEs) and high-voltage cathodes, and proposes strategies to stabilize the electrolyte/cathode interfaces. The future research direction of electrolyte/cathode interfaces and the application prospects of powder technology in sulfide-based ASSLBs are also discussed.