Genetic Nrf2 Overactivation Inhibits the Deleterious Effects Induced by Hepatocyte-Specific c-met Deletion during the Progression of NASH

Dysregulation of redox pathways in liver fibrosis

(2016) Natalie J. Torok   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Hepatocyte-specific Keap1 deletion reduces liver steatosis but not inflammation during non-alcoholic steatohepatitis development

(2016) Pierluigi Ramadori et al.   FREE RADICAL BIOLOGY AND MEDICINE

The therapeutic landscape of non-alcoholic steatohepatitis

(2016) Hugo Perazzo et al.   LIVER INTERNATIONAL

Induction of Nrf2-mediated phase II detoxifying/antioxidant enzymes in vitro by chitosan-caffeic acid against hydrogen peroxide-induced hepatotoxicity through JNK/ERK pathway

(2016) Chang-Bum Ahn et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

NAFLD causes selective CD4+ T lymphocyte loss and promotes hepatocarcinogenesis

(2016) Chi Ma et al.   NATURE

Non-alcoholic steatohepatitis: emerging molecular targets and therapeutic strategies

(2016) Giovanni Musso et al.   NATURE REVIEWS DRUG DISCOVERY

Hepatocyte Growth Factor Reduces Free Cholesterol-Mediated Lipotoxicity in Primary Hepatocytes by Countering Oxidative Stress

(2016) Mayra Domínguez-Pérez et al.   Oxidative Medicine and Cellular Longevity

Loss of c-Met signaling sensitizes hepatocytes to lipotoxicity and induces cholestatic liver damage by aggravating oxidative stress

(2016) Luis E. Gomez-Quiroz et al.   TOXICOLOGY

NADPH oxidase is implicated in the pathogenesis of oxidative phosphorylation dysfunction in mice fed a high-fat diet

(2016) Inmaculada García-Ruiz et al.   Scientific Reports

Myeloperoxidase–Hepatocyte–Stellate Cell Cross Talk Promotes Hepatocyte Injury and Fibrosis in Experimental Nonalcoholic Steatohepatitis

(2015) Benjamin Pulli et al.   ANTIOXIDANTS & REDOX SIGNALING

Nrf2 in health and disease: current and future clinical implications

(2015) O. Al-Sawaf et al.   CLINICAL SCIENCE

Molecular basis of the Keap1–Nrf2 system

(2015) Takafumi Suzuki et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hepatocyte specific deletion of c-Met leads to the development of severe non-alcoholic steatohepatitis in mice

(2014) Daniela C. Kroy et al.   JOURNAL OF HEPATOLOGY

Met signaling in cardiomyocytes is required for normal cardiac function in adult mice

(2013) María Arechederra et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Biphasic regulation of the NADPH oxidase by HGF/c-Met signaling pathway in primary mouse hepatocytes

(2013) Denise Clavijo-Cornejo et al.   BIOCHIMIE

Hepatocyte Growth Factor Protects Against Isoniazid/Rifampicin-Induced Oxidative Liver Damage

(2013) Cristina Enriquez-Cortina et al.   TOXICOLOGICAL SCIENCES

Hepatocyte growth factor/c-Met signalling is important for the selection of transplanted hepatocytes

(2012) Michaela Kaldenbach et al.   GUT

The central role of the c-Met pathway in rebuilding the liver

(2012) S S Thorgeirsson   GUT

Critical role of cytochrome P450 2E1 (CYP2E1) in the development of high fat-induced non-alcoholic steatohepatitis

(2012) Mohamed A. Abdelmegeed et al.   JOURNAL OF HEPATOLOGY

AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress

(2012) Sang-Min Jeon et al.   NATURE

Nrf2 Inhibits LXRα-Dependent Hepatic Lipogenesis by Competing with FXR for Acetylase Binding

(2011) Hee Yeon Kay et al.   ANTIOXIDANTS & REDOX SIGNALING

Antagonism of the chemokine Ccl5 ameliorates experimental liver fibrosis in mice

(2010) Marie-Luise Berres et al.   JOURNAL OF CLINICAL INVESTIGATION

c-Met Confers Protection Against Chronic Liver Tissue Damage and Fibrosis Progression After Bile Duct Ligation in Mice

(2009) Arne Giebeler et al.   GASTROENTEROLOGY

Hepatocyte-specific c-Met Deletion Disrupts Redox Homeostasis and Sensitizes to Fas-mediated Apoptosis

(2008) Luis E. Gómez-Quiroz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY