Fucoxanthin, a Marine Carotenoid, Attenuates β-Amyloid Oligomer-Induced Neurotoxicity Possibly via Regulating the PI3K/Akt and the ERK Pathways in SH-SY5Y Cells

Synaptotoxic Amyloid-β Oligomers: A Molecular Basis for the Cause, Diagnosis, and Treatment of Alzheimer's Disease?

(2018) William L. Klein   JOURNAL OF ALZHEIMERS DISEASE

Indirubin-3-Oxime Prevents H2O2-Induced Neuronal Apoptosis via Concurrently Inhibiting GSK3β and the ERK Pathway

(2016) Jie Yu et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

AChE and the amyloid precursor protein (APP) – Cross-talk in Alzheimer's disease

(2016) Natalia N. Nalivaeva et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Kinetics and molecular docking studies of fucosterol and fucoxanthin, BACE1 inhibitors from brown algae Undaria pinnatifida and Ecklonia stolonifera

(2016) Hyun Ah Jung et al.   FOOD AND CHEMICAL TOXICOLOGY

Peroxiredoxin 5 prevents amyloid-beta oligomer-induced neuronal cell death by inhibiting ERK–Drp1-mediated mitochondrial fragmentation

(2016) Bokyung Kim et al.   FREE RADICAL BIOLOGY AND MEDICINE

Multifunction of Chrysin in Parkinson’s Model: Anti-Neuronal Apoptosis, Neuroprotection via Activation of MEF2D, and Inhibition of Monoamine Oxidase-B

(2016) Baojian Guo et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Upstream regulators and downstream effectors of NF-κB in Alzheimer's disease

(2016) Zhe-Min Shi et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Alzheimer's disease

(2016) Philip Scheltens et al.   LANCET

Fucoxanthin, a Marine Carotenoid, Reverses Scopolamine-Induced Cognitive Impairments in Mice and Inhibits Acetylcholinesterase in Vitro

(2016) Jiajia Lin et al.   Marine Drugs

Marine Algae as a Potential Source for Anti-Obesity Agents

(2016) Chu Wan-Loy et al.   Marine Drugs

Molecular Mechanisms of Amyloid Oligomers Toxicity

(2016) Rakez Kayed et al.   JOURNAL OF ALZHEIMERS DISEASE

Fucoxanthin Inhibits the Inflammation Response in Paw Edema Model through Suppressing MAPKs, Akt, and NFκB

(2015) Jun-Hui Choi et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Indirubin-3-Oxime Effectively Prevents 6OHDA-Induced Neurotoxicity in PC12 Cells via Activating MEF2D Through the Inhibition of GSK3β

(2015) Shengquan Hu et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Anti-Obesity Activity of the Marine Carotenoid Fucoxanthin

(2015) Maria Gammone et al.   Marine Drugs

Marine Carotenoids against Oxidative Stress: Effects on Human Health

(2015) Maria Gammone et al.   Marine Drugs

Bis(propyl)-cognitin Prevents β-amyloid-induced Memory Deficits as Well as Synaptic Formation and Plasticity Impairments via the Activation of PI3-K Pathway

(2015) Liting Jiang et al.   MOLECULAR NEUROBIOLOGY

Dicyanovinyl-substituted J147 analogue inhibits oligomerization and fibrillation of β-amyloid peptides and protects neuronal cells from β-amyloid-induced cytotoxicity

(2015) Kyoungdo Kim et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Sunitinib Produces Neuroprotective Effect Via Inhibiting Nitric Oxide Overproduction

(2014) Wei Cui et al.   CNS Neuroscience & Therapeutics

Beyond Acetylcholinesterase Inhibitors for Treating Alzheimer&aposs Disease: .α7-nAChR Agonists in Human Clinical Trials

(2014) Patrizia Russo et al.   CURRENT PHARMACEUTICAL DESIGN

Inhibiting β-Amyloid-Associated Alzheimer’s Pathogenesis In Vitro and In Vivo by a Multifunctional Dimeric Bis(12)-hupyridone Derived from Its Natural Analogue

(2014) Shengquan Hu et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Fucoxanthin Enhances the Level of Reduced Glutathione via the Nrf2-Mediated Pathway in Human Keratinocytes

(2014) Jian Zheng et al.   Marine Drugs

The phosphorylation of Hsp20 enhances its association with amyloid-β to increase protection against neuronal cell death

(2014) Ryan T. Cameron et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Fucoxanthin Ameliorates Inflammation and Oxidative Reponses in Microglia

(2013) Ratih Pangestuti et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The anti-cancer agent SU4312 unexpectedly protects against MPP+-induced neurotoxicity via selective and direct inhibition of neuronal NOS

(2012) Wei Cui et al.   BRITISH JOURNAL OF PHARMACOLOGY

Unexpected Neuronal Protection of SU5416 against 1-Methyl-4-Phenylpyridinium Ion-Induced Toxicity via Inhibiting Neuronal Nitric Oxide Synthase

(2012) Wei Cui et al.   PLoS One

Research update: Alpha7 nicotinic acetylcholine receptor mechanisms in Alzheimer's disease

(2011) H. Rheinallt Parri et al.   BIOCHEMICAL PHARMACOLOGY

Age-dependent Accumulation of Soluble Amyloid β (Aβ) Oligomers Reverses the Neuroprotective Effect of Soluble Amyloid Precursor Protein-α (sAPPα) by Modulating Phosphatidylinositol 3-Kinase (PI3K)/Akt-GSK-3β Pathway in Alzheimer Mouse Model

(2011) Sebastian Jimenez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuroprotective Effects of Marine Algae

(2011) Ratih Pangestuti et al.   Marine Drugs

The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer’s disease

(2011) Sergio T. Ferreira et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Fucoxanthin inhibits the inflammatory response by suppressing the activation of NF-κB and MAPKs in lipopolysaccharide-induced RAW 264.7 macrophages

(2010) Kil-Nam Kim et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

An improved method for generating consistent soluble amyloid-beta oligomer preparations for in vitro neurotoxicity studies

(2010) Deborah A. Ryan et al.   JOURNAL OF NEUROSCIENCE METHODS

The effects of Xanthigen™in the weight management of obese premenopausal women with non-alcoholic fatty liver disease and normal liver fat

(2009) M. Abidov et al.   DIABETES OBESITY & METABOLISM

Protective effect of fucoxanthin isolated from Sargassum siliquastrum on UV-B induced cell damage

(2008) Soo-Jin Heo et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY