期刊
ORGANIC LETTERS
卷 19, 期 19, 页码 5388-5391出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.7b02669
关键词
-
资金
- JSPS KAKENHI [15H04634, 15K18833, 17K08214]
- Society of Synthetic Organic Chemistry (Japan)
- Uehara Memorial Foundation
- Ministry of Education, Culture, Sports, Science and Technology (MEXT)
- Japan Agency for Medical Research and Development (AMED)
- Grants-in-Aid for Scientific Research [15H04634, 15K18833, 17K08214] Funding Source: KAKEN
The direct C3-arylation of N-unsubstituted indoles with aryl chlorides and triflates has been realized using a palladium-dihydroxyterphenylphosphine (DHTP) catalyst. The site selectivity is different from that obtained with other structurally related ligands. This unique feature of the DHTP ligand is attributed to complex formation between the lithium salts of the ligand and the indole. The method was applied to the late-stage derivatization of pharmaceuticals having a chloro group.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据