期刊
ORGANIC LETTERS
卷 19, 期 24, 页码 6630-6633出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.7b03342
关键词
-
资金
- Ministry of Education (Singapore)
- Nanyang Technological University [RG 3/15, RG 114/15, MOE2016-T2-2-043]
A chromium/2,2'-bipyridine-catalyzed annulation reaction of 2-biarylmagnesium reagents with alkynes is reported. The reaction is applicable to a variety of aryl-and/or alkyl-substituted internal alkynes as well as 2-biaryl and related Grignard reagents, thus affording phenanthrene derivatives in moderate to good yields. The reaction proceeds at the expense of excess alkyne as a hydrogen acceptor and thus does not need an external oxidant. Deuterium-labeling experiments shed light on the reaction mechanism, which likely involves multiple intramolecular C-H activation processes on chromium.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据