期刊
ORGANIC LETTERS
卷 19, 期 9, 页码 2226-2229出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.7b00678
关键词
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资金
- NSFC [21402128, 21502042]
- Beijing Natural Science Foundation [2172015, 2144045]
- Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education)
- Capital Normal University
An iron-catalyzed dehydrogenative sp(3)-sp(2) coupling of acetonitrile and 2-arylimidazo[1,2-a]pyridine has been realized, which can serve as a novel approach toward heteroarylacetonitriles. The merit of this strategy is illustrated by the breadth of functional groups tolerated in the transformation and the fast access to pharmaceuticals (such as zolpidem) directly from the heteroarylacetonitriles.
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