LncRNA HULC triggers autophagy via stabilizing Sirt1 and attenuates the chemosensitivity of HCC cells

PSMD10/gankyrin induces autophagy to promote tumor progression through cytoplasmic interaction with ATG7 and nuclear transactivation of ATG7 expression

(2015) Tao Luo et al.   Autophagy

Burkholderia pseudomalleisurvival in lung epithelial cells benefits from miRNA-mediated suppression of ATG10

(2015) Qian Li et al.   Autophagy

Downregulation of ATG14 by EGR1-MIR152 sensitizes ovarian cancer cells to cisplatin-induced apoptosis by inhibiting cyto-protective autophagy

(2015) Jun He et al.   Autophagy

Heparanase Enhances Tumor Growth and Chemoresistance by Promoting Autophagy

(2015) Anna Shteingauz et al.   CANCER RESEARCH

Long Noncoding RNA HULC Modulates Abnormal Lipid Metabolism in Hepatoma Cells through an miR-9-Mediated RXRA Signaling Pathway

(2015) M. Cui et al.   CANCER RESEARCH

SIRT1 is a regulator of autophagy: Implications in gastric cancer progression and treatment

(2015) Guanglin Qiu et al.   FEBS LETTERS

hTERT promotes the invasion of gastric cancer cells by enhancing FOXO3a ubiquitination and subsequent ITGB1 upregulation

(2015) Changjiang Hu et al.   GUT

Ubiquitinated Sirtuin 1 (SIRT1) Function Is Modulated during DNA Damage-induced Cell Death and Survival

(2015) Lirong Peng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High USP22 expression indicates poor prognosis in hepatocellular carcinoma

(2015) Bo Tang et al.   Oncotarget

Metformin alleviates hepatosteatosis by restoring SIRT1-mediated autophagy induction via an AMP-activated protein kinase-independent pathway

(2014) Young Mi Song et al.   Autophagy

Inhibition of p53 increases chemosensitivity to 5-FU in nutrient-deprived hepatocarcinoma cells by suppressing autophagy

(2014) Xian-ling Guo et al.   CANCER LETTERS

SIRT1 Activation by a c-MYC Oncogenic Network Promotes the Maintenance and Drug Resistance of Human FLT3-ITD Acute Myeloid Leukemia Stem Cells

(2014) Ling Li et al.   Cell Stem Cell

MicroRNA-363-mediated downregulation of S1PR1 suppresses the proliferation of hepatocellular carcinoma cells

(2014) Peng Zhou et al.   CELLULAR SIGNALLING

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

USP22 Regulates Oncogenic Signaling Pathways to Drive Lethal Cancer Progression

(2013) R. S. Schrecengost et al.   CANCER RESEARCH

Mapping the Human miRNA Interactome by CLASH Reveals Frequent Noncanonical Binding

(2013) Aleksandra Helwak et al.   CELL

Long Noncoding RNAs: Cellular Address Codes in Development and Disease

(2013) Pedro J. Batista et al.   CELL

lincRNAs: Genomics, Evolution, and Mechanisms

(2013) Igor Ulitsky et al.   CELL

Posttranscriptional destabilization of the liver-specific long noncoding RNA HULC by the IGF2 mRNA-binding protein 1 (IGF2BP1)

(2013) Monika Hämmerle et al.   HEPATOLOGY

A High-Confidence Interaction Map Identifies SIRT1 as a Mediator of Acetylation of USP22 and the SAGA Coactivator Complex

(2013) S. M. Armour et al.   MOLECULAR AND CELLULAR BIOLOGY

A biophysical miRNA-mRNA interaction model infers canonical and noncanonical targets

(2013) Mohsen Khorshid et al.   NATURE METHODS

MicroRNA-29c functions as a tumor suppressor by direct targeting oncogenic SIRT1 in hepatocellular carcinoma

(2013) H J Bae et al.   ONCOGENE

LXRα-mediated downregulation of FOXM1 suppresses the proliferation of hepatocellular carcinoma cells

(2013) C Hu et al.   ONCOGENE

Epidemiology of Viral Hepatitis and Hepatocellular Carcinoma

(2012) Hashem B. El-Serag   GASTROENTEROLOGY

Elevation of Highly Up-regulated in Liver Cancer (HULC) by Hepatitis B Virus X Protein Promotes Hepatoma Cell Proliferation via Down-regulating p18

(2012) Yumei Du et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

USP22 Antagonizes p53 Transcriptional Activation by Deubiquitinating Sirt1 to Suppress Cell Apoptosis and Is Required for Mouse Embryonic Development

(2012) Zhenghong Lin et al.   MOLECULAR CELL

SIRT1 Promotes Tumorigenesis and Resistance to Chemotherapy in Hepatocellular Carcinoma and its Expression Predicts Poor Prognosis

(2011) Hsieh-Cheng Chen et al.   ANNALS OF SURGICAL ONCOLOGY

Sirtuin 1 Is Upregulated in a Subset of Hepatocellular Carcinomas where It Is Essential for Telomere Maintenance and Tumor Cell Growth

(2011) J. Chen et al.   CANCER RESEARCH

Sirtuin 1 (SIRT1) Protein Degradation in Response to Persistent c-Jun N-terminal Kinase 1 (JNK1) Activation Contributes to Hepatic Steatosis in Obesity

(2011) Zhanguo Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes

(2010) Nirmala Hariharan et al.   CIRCULATION RESEARCH

CREB up-regulates long non-coding RNA, HULC expression through interaction with microRNA-372 in liver cancer

(2010) Jiayi Wang et al.   NUCLEIC ACIDS RESEARCH

Hypoxia-induced autophagy contributes to the chemoresistance of hepatocellular carcinoma cells

(2009) Jianrui Song et al.   Autophagy

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

The Putative Cancer Stem Cell Marker USP22 Is a Subunit of the Human SAGA Complex Required for Activated Transcription and Cell-Cycle Progression

(2008) Xiao-Yong Zhang et al.   MOLECULAR CELL

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

(2008) I. H. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA