Multimerin-2 is a ligand for group 14 family C-type lectins CLEC14A, CD93 and CD248 spanning the endothelial pericyte interface

Elevated expression of CD93 promotes angiogenesis and tumor growth in nasopharyngeal carcinoma

(2016) Lili Bao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sprouting angiogenesis is regulated by shedding of the C-type lectin family 14, member A (CLEC14A) ectodomain, catalyzed by rhomboid-like 2 protein (RHBDL2)

(2016) Peter J. Noy et al.   FASEB JOURNAL

Elevated Expression of the C-Type Lectin CD93 in the Glioblastoma Vasculature Regulates Cytoskeletal Rearrangements That Enhance Vessel Function and Reduce Host Survival

(2015) Elise Langenkamp et al.   CANCER RESEARCH

CD93 gene polymorphism is associated with disseminated colorectal cancer

(2015) Renate S. Olsen et al.   INTERNATIONAL JOURNAL OF COLORECTAL DISEASE

The I-TASSER Suite: protein structure and function prediction

(2015) Jianyi Yang et al.   NATURE METHODS

Blocking CLEC14A-MMRN2 binding inhibits sprouting angiogenesis and tumour growth

(2015) P J Noy et al.   ONCOGENE

MULTIMERIN2 binds VEGF-A primarily via the carbohydrate chains exerting an angiostatic function and impairing tumor growth

(2015) Roberta Colladel et al.   Oncotarget

A First-in-Human Phase I Study of MORAb-004, a Monoclonal Antibody to Endosialin in Patients with Advanced Solid Tumors

(2014) L. A. Diaz et al.   CLINICAL CANCER RESEARCH

RhoJ interacts with the GIT-PIX complex and regulates focal adhesion disassembly

(2014) E. Wilson et al.   JOURNAL OF CELL SCIENCE

A Core Human Primary Tumor Angiogenesis Signature Identifies the Endothelial Orphan Receptor ELTD1 as a Key Regulator of Angiogenesis

(2013) Massimo Masiero et al.   CANCER CELL

SILAC-Based Proteomics of Human Primary Endothelial Cell Morphogenesis Unveils Tumor Angiogenic Markers

(2013) Sara Zanivan et al.   MOLECULAR & CELLULAR PROTEOMICS

Human antibodies targeting the C-type lectin-like domain of the tumor endothelial cell marker clec14a regulate angiogenic properties in vitro

(2013) M K Ki et al.   ONCOGENE

The mesenchymal stem cell marker CD248 (endosialin) is a negative regulator of bone formation in mice

(2012) Amy J. Naylor et al.   ARTHRITIS AND RHEUMATISM

Pericytes promote selective vessel regression to regulate vascular patterning

(2012) N. Simonavicius et al.   BLOOD

MULTIMERIN2 impairs tumor angiogenesis and growth by interfering with VEGF-A/VEGFR2 pathway

(2011) E Lorenzon et al.   ONCOGENE

Identification and angiogenic role of the novel tumor endothelial marker CLEC14A

(2011) M Mura et al.   ONCOGENE

RhoJ/TCL Regulates Endothelial Motility and Tube Formation and Modulates Actomyosin Contractility and Focal Adhesion Numbers

(2010) Sukhbir Kaur et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Clec14a is specifically expressed in endothelial cells and mediates cell to cell adhesion

(2010) Seung-Sik Rho et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Endosialin (CD248) is a marker of tumor-associated pericytes in high-grade glioma

(2008) Nicole Simonavicius et al.   MODERN PATHOLOGY