Activation of tumor suppressor LKB1 by honokiol abrogates cancer stem-like phenotype in breast cancer via inhibition of oncogenic Stat3

Inhibition of NADPH oxidase 1 activity and blocking the binding of cytosolic and membrane-bound proteins by honokiol inhibit migratory potential of melanoma cells

(2016) Ram Prasad et al.   Oncotarget

Confinement Sensing and Signal Optimization via Piezo1/PKA and Myosin II Pathways

(2016) Wei-Chien Hung et al.   Cell Reports

Honokiol abrogates leptin-induced tumor progression by inhibiting Wnt1-MTA1-β-catenin signaling axis in a microRNA-34a dependent manner

(2015) Dimiter B. Avtanski et al.   Oncotarget

Pre-clinical study of drug combinations that reduce breast cancer burden due to aberrant mTOR and metabolism promoted by LKB1 loss

(2015) Rafaela Andrade-Vieira et al.   Oncotarget

Hepatitis C virus core protein regulates NANOG expression via the stat3 pathway

(2014) Jia-Jia Zhou et al.   FEBS LETTERS

Loss of LKB1 disrupts breast epithelial cell polarity and promotes breast cancer metastasis and invasion

(2014) Juan Li et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Honokiol inhibits epithelial-mesenchymal transition in breast cancer cells by targeting signal transducer and activator of transcription 3/Zeb1/E-cadherin axis

(2014) Dimiter B. Avtanski et al.   Molecular Oncology

Fluid shear promotes chondrosarcoma cell invasion by activating matrix metalloproteinase 12 via IGF-2 and VEGF signaling pathways

(2014) P Wang et al.   ONCOGENE

A genetic and developmental pathway from STAT3 to the OCT4-NANOG circuit is essential for maintenance of ICM lineages in vivo

(2013) D. V. Do et al.   GENES & DEVELOPMENT

Distinct signaling mechanisms regulate migration in unconfined versus confined spaces

(2013) Wei-Chien Hung et al.   JOURNAL OF CELL BIOLOGY

Loss of lkb1 Expression Reduces the Latency of ErbB2-Mediated Mammary Gland Tumorigenesis, Promoting Changes in Metabolic Pathways

(2013) Rafaela Andrade-Vieira et al.   PLoS One

Leptin-induced Epithelial-Mesenchymal Transition in Breast Cancer Cells Requires β-Catenin Activation via Akt/GSK3- and MTA1/Wnt1 Protein-dependent Pathways

(2012) Dan Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

Antioxidant properties of natural polyphenols and their therapeutic potentials for Alzheimer's disease

(2011) Dong-Young Choi et al.   BRAIN RESEARCH BULLETIN

Stat3 Mediates Expression of Autotaxin in Breast Cancer

(2011) Janeen Azare et al.   PLoS One

Honokiol Inhibits Epidermal Growth Factor Receptor Signaling and Enhances the Antitumor Effects of Epidermal Growth Factor Receptor Inhibitors

(2010) R. J. Leeman-Neill et al.   CLINICAL CANCER RESEARCH

Molecular mechanisms of tumor suppression by LKB1

(2010) Kari Vaahtomeri et al.   FEBS LETTERS

LKB1 Haploinsufficiency Cooperates With Kras to Promote Pancreatic Cancer Through Suppression of p21-Dependent Growth Arrest

(2010) Jennifer P. Morton et al.   GASTROENTEROLOGY

Anti-inflammatory effect of 4-O-methylhonokiol, a novel compound isolated from Magnolia officinalis through inhibition of NF-κB

(2009) Ju Hoon Oh et al.   CHEMICO-BIOLOGICAL INTERACTIONS

LKB1 Catalytic Activity Contributes to Estrogen Receptor α Signaling

(2009) Suchita Nath-Sain et al.   MOLECULAR BIOLOGY OF THE CELL

LKB1 is required for adiponectin-mediated modulation of AMPK–S6K axis and inhibition of migration and invasion of breast cancer cells

(2009) L Taliaferro-Smith et al.   ONCOGENE

Bidirectional Crosstalk between Leptin and Insulin-like Growth Factor-I Signaling Promotes Invasion and Migration of Breast Cancer Cells via Transactivation of Epidermal Growth Factor Receptor

(2008) N. K. Saxena et al.   CANCER RESEARCH

Module Map of Stem Cell Genes Guides Creation of Epithelial Cancer Stem Cells

(2008) David J. Wong et al.   Cell Stem Cell

Targeting STAT3 in cancer: how successful are we?

(2008) Peibin Yue et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors

(2008) Ittai Ben-Porath et al.   NATURE GENETICS

Regulation of Sox2 by STAT3 Initiates Commitment to the Neural Precursor Cell Fate

(2008) Kara M. Foshay et al.   STEM CELLS AND DEVELOPMENT

Antidepressant-like effects of the mixture of honokiol and magnolol from the barks of Magnolia officinalis in stressed rodents

(2007) Qun Xu et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY