SOX9 activity is induced by oncogenic Kras to affect MDC1 and MCMs expression in pancreatic cancer

Genetics and biology of pancreatic ductal adenocarcinoma

(2016) Haoqiang Ying et al.   GENES & DEVELOPMENT

SOX9 expression predicts relapse of stage II colon cancer patients

(2016) Maiken Lise Marcker Espersen et al.   HUMAN PATHOLOGY

Growth and metastasis of lung adenocarcinoma is potentiated by BMP4-mediated immunosuppression

(2016) Limo Chen et al.   OncoImmunology

MDC1 Enhances Estrogen Receptor-mediated Transactivation and Contributes to Breast Cancer Suppression

(2015) Renlong Zou et al.   International Journal of Biological Sciences

MDC1 functionally identified as an androgen receptor co-activator participates in suppression of prostate cancer

(2015) Chunyu Wang et al.   NUCLEIC ACIDS RESEARCH

SLUG is required for SOX9 stabilization and functions to promote cancer stem cells and metastasis in human lung carcinoma

(2015) S Luanpitpong et al.   ONCOGENE

Upregulation of sex-determining region Y-box 9 (SOX9) promotes cell proliferation and tumorigenicity in esophageal squamous cell carcinoma

(2015) Yingcai Hong et al.   Oncotarget

SOX9, a potential tumor suppressor in cervical cancer, transactivates p21WAF1/CIP1 and suppresses cervical tumor growth

(2015) Hai-yan Wang et al.   Oncotarget

SOX9 regulates ERBB signalling in pancreatic cancer development

(2014) Adrien Grimont et al.   GUT

Clinical implication of Sox9 and activated Akt expression in pancreatic ductal adenocarcinoma

(2014) Suhua Xia et al.   MEDICAL ONCOLOGY

Cooperativity of Oncogenic K-Ras and Downregulated p16/INK4A in Human Pancreatic Tumorigenesis

(2014) Zhe Chang et al.   PLoS One

The Mcm2-7 Replicative Helicase: A Promising Chemotherapeutic Target

(2014) Nicholas E. Simon et al.   Biomed Research International

Deciphering the Mechanisms of Tumorigenesis in Human Pancreatic Ductal Epithelial Cells

(2013) Z. Chang et al.   CLINICAL CANCER RESEARCH

Roles for KRAS in Pancreatic Tumor Development and Progression

(2013) Marina Pasca di Magliano et al.   GASTROENTEROLOGY

Sox9 and programming of liver and pancreatic progenitors

(2013) Yoshiya Kawaguchi   JOURNAL OF CLINICAL INVESTIGATION

Epigenetic Regulation of SOX9 by the NF-κB Signaling Pathway in Pancreatic Cancer Stem Cells

(2013) Lei Sun et al.   STEM CELLS

The Role of SOX9 Transcription Factor in Pancreatic and Duodenal Development

(2013) Jamie Belo et al.   STEM CELLS AND DEVELOPMENT

Transcriptional Up-Regulation of Sox9 by NF-κB in Endometrial Carcinoma Cells, Modulating Cell Proliferation Through Alteration in the p14 ARF /p53/p21 WAF1 Pathway

(2012) Makoto Saegusa et al.   AMERICAN JOURNAL OF PATHOLOGY

Identification of Sox9-Dependent Acinar-to-Ductal Reprogramming as the Principal Mechanism for Initiation of Pancreatic Ductal Adenocarcinoma

(2012) Janel L. Kopp et al.   CANCER CELL

KrasG12D-Induced IKK2/β/NF-κB Activation by IL-1α and p62 Feedforward Loops Is Required for Development of Pancreatic Ductal Adenocarcinoma

(2012) Jianhua Ling et al.   CANCER CELL

Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism

(2012) Haoqiang Ying et al.   CELL

Modulation of Pancreatic Cancer Chemoresistance by Inhibition of TAK1

(2011) Davide Melisi et al.   JNCI-Journal of the National Cancer Institute

Bone morphogenetic protein 4 (BMP4) is required for migration and invasion of breast cancer

(2011) Dan Guo et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

The cellular response to DNA damage: A focus on MDC1 and its interacting proteins

(2011) Gideon Coster et al.   Nucleus

Prognostic value of interleukin 2 and interleukin 15 in peritumoral hepatic tissues for patients with hepatitis B-related hepatocellular carcinoma after curative resection

(2010) Haijun Zhou et al.   GUT

β-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice

(2010) John P. Morris et al.   JOURNAL OF CLINICAL INVESTIGATION

Oncogenic Activation of NF- B

(2010) L. M. Staudt   Cold Spring Harbor Perspectives in Biology

Secreted Interleukin-1  Induces a Metastatic Phenotype in Pancreatic Cancer by Sustaining a Constitutive Activation of Nuclear Factor- B

(2009) D. Melisi et al.   MOLECULAR CANCER RESEARCH

MDC1 regulates intra-S-phase checkpoint by targeting NBS1 to DNA double-strand breaks

(2008) L. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA