期刊
OCULAR SURFACE
卷 15, 期 1, 页码 65-76出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jtos.2016.09.003
关键词
consensus; definition of dry eye; diagnosis of dry eye; dry eye; tear film breakup time; tear film oriented therapy
资金
- Santen Pharmaceutical Co., Ltd
- Otsuka Pharmaceutical Co., Ltd.
- Senju Pharmaceutical Co., Ltd.
- Grants-in-Aid for Scientific Research [16K11269] Funding Source: KAKEN
For the last 20 years, a great amount of evidence has accumulated through epidemiological studies that most of the dry eye disease encountered in daily life, especially in video display terminal (VDT) workers, involves short tear film breakup time (TFBUT) type dry eye, a category characterized by severe symptoms but minimal clinical signs other than short TFBUT. An unstable tear film also affects the visual function, possibly due to the increase of higher order aberrations. Based on the change in the understanding of the types, symptoms, and signs of dry eye disease, the Asia Dry Eye Society agreed to the following definition of dry eye: Dry eye is a multifactorial disease characterized by unstable tear film causing a variety of symptoms and/or visual impairment, potentially accompanied by ocular surface damage. The definition stresses instability of the tear film as well as the importance of visual impairment, highlighting an essential role for TFBUT assessment. This paper discusses the concept of Tear Film Oriented Therapy (TFOT), which evolved from the definition of dry eye, emphasizing the importance of a stable tear film.
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