DNA-assisted oligomerization of pore-forming toxin monomers into precisely-controlled protein channels

Large-Conductance Transmembrane Porin Made from DNA Origami

(2016) Kerstin Göpfrich et al.   ACS Nano

Quantifying Nanomolar Protein Concentrations Using Designed DNA Carriers and Solid-State Nanopores

(2016) Jinglin Kong et al.   NANO LETTERS

Real-time, portable genome sequencing for Ebola surveillance

(2016) Joshua Quick et al.   NATURE

Digitally encoded DNA nanostructures for multiplexed, single-molecule protein sensing with nanopores

(2016) Nicholas A. W. Bell et al.   Nature Nanotechnology

Molecular transport through large-diameter DNA nanopores

(2016) Swati Krishnan et al.   Nature Communications

Ionic Conductivity, Structural Deformation, and Programmable Anisotropy of DNA Origami in Electric Field

(2015) Chen-Yu Li et al.   ACS Nano

Selective Detection of Protein Homologues in Serum Using an OmpG Nanopore

(2015) Monifa A. Fahie et al.   ANALYTICAL CHEMISTRY

Pim Kinase Inhibitors Evaluated with a Single-Molecule Engineered Nanopore Sensor

(2015) Leon Harrington et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Molecular Dynamics of Membrane-Spanning DNA Channels: Conductance Mechanism, Electro-Osmotic Transport, and Mechanical Gating

(2015) Jejoong Yoo et al.   Journal of Physical Chemistry Letters

Single-Molecule Analyte Recognition with ClyA Nanopores Equipped with Internal Protein Adaptors

(2015) Misha Soskine et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DNA-Tile Structures Induce Ionic Currents through Lipid Membranes

(2015) Kerstin Göpfrich et al.   NANO LETTERS

Complex wireframe DNA origami nanostructures with multi-arm junction vertices

(2015) Fei Zhang et al.   Nature Nanotechnology

Detection of Two Isomeric Binding Configurations in a Protein–Aptamer Complex with a Biological Nanopore

(2014) Veerle Van Meervelt et al.   ACS Nano

Stochastic transport through carbon nanotubes in lipid bilayers and live cell membranes

(2014) Jia Geng et al.   NATURE

Computational design of water-soluble α-helical barrels

(2014) Andrew R. Thomson et al.   SCIENCE

Ion Channel Models Based on Self-Assembling Cyclic Peptide Nanotubes

(2013) Javier Montenegro et al.   ACCOUNTS OF CHEMICAL RESEARCH

Ionic Permeability and Mechanical Properties of DNA Origami Nanoplates on Solid-State Nanopores

(2013) Calin Plesa et al.   ACS Nano

Engineered Nanopore of Phi29 DNA-Packaging Motor for Real-Time Detection of Single Colon Cancer Specific Antibody in Serum

(2013) Shaoying Wang et al.   ACS Nano

Lipid-Bilayer-Spanning DNA Nanopores with a Bifunctional Porphyrin Anchor

(2013) Jonathan R. Burns et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tuning the Size and Properties of ClyA Nanopores Assisted by Directed Evolution

(2013) Misha Soskine et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-Assembled DNA Nanopores That Span Lipid Bilayers

(2013) Jonathan R. Burns et al.   NANO LETTERS

Multistep protein unfolding during nanopore translocation

(2013) David Rodriguez-Larrea et al.   Nature Nanotechnology

An engineered dimeric protein pore that spans adjacent lipid bilayers

(2013) Shiksha Mantri et al.   Nature Communications

Sequence-dependent thermodynamics of a coarse-grained DNA model

(2012) Petr Šulc et al.   JOURNAL OF CHEMICAL PHYSICS

Lipid Dynamics and Protein–Lipid Interactions in 2D Crystals Formed with the β-Barrel Integral Membrane Protein VDAC1

(2012) Matthew T. Eddy et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Reading DNA at single-nucleotide resolution with a mutant MspA nanopore and phi29 DNA polymerase

(2012) Elizabeth A Manrao et al.   NATURE BIOTECHNOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Synthetic Lipid Membrane Channels Formed by Designed DNA Nanostructures

(2012) M. Langecker et al.   SCIENCE

Dynamics of Unfolded Protein Transport through an Aerolysin Pore

(2011) Manuela Pastoriza-Gallego et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Orthogonal Protein Decoration of DNA Origami

(2010) Barbara Saccà et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Applications of biological pores in nanomedicine, sensing, and nanoelectronics

(2010) Sheereen Majd et al.   CURRENT OPINION IN BIOTECHNOLOGY

Self-assembly of DNA into nanoscale three-dimensional shapes

(2009) Shawn M. Douglas et al.   NATURE

Continuous base identification for single-molecule nanopore DNA sequencing

(2009) James Clarke et al.   Nature Nanotechnology

Artificial β-Barrels

(2008) Naomi Sakai et al.   ACCOUNTS OF CHEMICAL RESEARCH