The effect of increasing numbers of repeats on TAL effector DNA binding specificity

TALE proteins search DNA using a rotationally decoupled mechanism

(2016) Luke Cuculis et al.   Nature Chemical Biology

Improved specificity of TALE-based genome editing using an expanded RVD repertoire

(2015) Jeffrey C Miller et al.   NATURE METHODS

Refined Requirements for Protein Regions Important for Activity of the TALE AvrBs3

(2015) Tom Schreiber et al.   PLoS One

Direct observation of TALE protein dynamics reveals a two-state search mechanism

(2015) Luke Cuculis et al.   Nature Communications

Context influences on TALE–DNA binding revealed by quantitative profiling

(2015) Julia M. Rogers et al.   Nature Communications

TAL effectors: tools for DNA Targeting

(2014) R. Jankele et al.   Briefings in Functional Genomics

Complete decoding of TAL effectors for DNA recognition

(2014) Junjiao Yang et al.   CELL RESEARCH

Principles and applications of TAL effectors for plant physiology and metabolism

(2014) Adam J Bogdanove   CURRENT OPINION IN PLANT BIOLOGY

TAL effectors - pathogen strategies and plant resistance engineering

(2014) Jens Boch et al.   NEW PHYTOLOGIST

An online bioinformatics tool predicts zinc finger and TALE nuclease off-target cleavage

(2014) Eli J. Fine et al.   NUCLEIC ACIDS RESEARCH

Repeat 1 of TAL effectors affects target specificity for the base at position zero

(2014) T. Schreiber et al.   NUCLEIC ACIDS RESEARCH

Comprehensive analysis of the specificity of transcription activator-like effector nucleases

(2014) Alexandre Juillerat et al.   NUCLEIC ACIDS RESEARCH

From dead leaf, to new life: TAL effectors as tools for synthetic biology

(2014) Orlando de Lange et al.   PLANT JOURNAL

Code-Assisted Discovery of TAL Effector Targets in Bacterial Leaf Streak of Rice Reveals Contrast with Bacterial Blight and a Novel Susceptibility Gene

(2014) Raul A. Cernadas et al.   PLoS Pathogens

BuD, a helix–loop–helix DNA-binding domain for genome modification

(2014) Stefano Stella et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structure of the AvrBs3–DNA complex provides new insights into the initial thymine-recognition mechanism

(2013) Stefano Stella et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Robust, synergistic regulation of human gene expression using TALE activators

(2013) Morgan L Maeder et al.   NATURE METHODS

TALE-mediated modulation of transcriptional enhancers in vivo

(2013) Justin Crocker et al.   NATURE METHODS

Quantitative analysis of TALE–DNA interactions suggests polarity effects

(2013) Joshua F. Meckler et al.   NUCLEIC ACIDS RESEARCH

megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering

(2013) Sandrine Boissel et al.   NUCLEIC ACIDS RESEARCH

An Improved Method for TAL Effectors DNA-Binding Sites Prediction Reveals Functional Convergence in TAL Repertoires of Xanthomonas oryzae Strains

(2013) Alvaro L. Pérez-Quintero et al.   PLoS One

TAL Effectors Specificity Stems from Negative Discrimination

(2013) Basile I. M. Wicky et al.   PLoS One

TAL Effector Specificity for base 0 of the DNA Target Is Altered in a Complex, Effector- and Assay-Dependent Manner by Substitutions for the Tryptophan in Cryptic Repeat –1

(2013) Erin L. Doyle et al.   PLoS One

TAL effectors: highly adaptable phytobacterial virulence factors and readily engineered DNA-targeting proteins

(2013) Erin L. Doyle et al.   TRENDS IN CELL BIOLOGY

Crystal structure of a TALE protein reveals an extended N-terminal DNA binding region

(2012) Haishan Gao et al.   CELL RESEARCH

Artificial repressors for controlling gene expression in bacteria

(2012) Mark C. Politz et al.   CHEMICAL COMMUNICATIONS

High-efficiency TALEN-based gene editing produces disease-resistant rice

(2012) Ting Li et al.   NATURE BIOTECHNOLOGY

TAL effector RVD specificities and efficiencies

(2012) Jana Streubel et al.   NATURE BIOTECHNOLOGY

Engineering synthetic TAL effectors with orthogonal target sites

(2012) Abhishek Garg et al.   NUCLEIC ACIDS RESEARCH

Rational Diversification of a Promoter Providing Fine-Tuned Expression and Orthogonal Regulation for Synthetic Biology

(2012) Benjamin A. Blount et al.   PLoS One

The Crystal Structure of TAL Effector PthXo1 Bound to Its DNA Target

(2012) A. N.-S. Mak et al.   SCIENCE

Structural Basis for Sequence-Specific Recognition of DNA by TAL Effectors

(2012) D. Deng et al.   SCIENCE

Comprehensive interrogation of natural TALE DNA-binding modules and transcriptional repressor domains

(2012) Le Cong et al.   Nature Communications

Colonization of Rice Leaf Blades by an African Strain of Xanthomonas oryzae pv. oryzae Depends on a New TAL Effector That Induces the Rice Nodulin-3 Os11N3 Gene

(2011) Yanhua Yu et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

Targeted gene disruption in somatic zebrafish cells using engineered TALENs

(2011) Jeffry D Sander et al.   NATURE BIOTECHNOLOGY

Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting

(2011) Tomas Cermak et al.   NUCLEIC ACIDS RESEARCH

Targeted transcriptional repression using a chimeric TALE-SRDX repressor protein

(2011) Magdy M. Mahfouz et al.   PLANT MOLECULAR BIOLOGY

XanthomonasAvrBs3 Family-Type III Effectors: Discovery and Function

(2010) Jens Boch et al.   Annual Review of Phytopathology

TAL effectors: finding plant genes for disease and defense

(2010) Adam J Bogdanove et al.   CURRENT OPINION IN PLANT BIOLOGY

Targeting DNA Double-Strand Breaks with TAL Effector Nucleases

(2010) M. Christian et al.   GENETICS

A TALE nuclease architecture for efficient genome editing

(2010) Jeffrey C Miller et al.   NATURE BIOTECHNOLOGY

Regulation of selected genome loci using de novo-engineered transcription activator-like effector (TALE)-type transcription factors

(2010) R. Morbitzer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Breaking the Code of DNA Binding Specificity of TAL-Type III Effectors

(2009) J. Boch et al.   SCIENCE

A Simple Cipher Governs DNA Recognition by TAL Effectors

(2009) M. J. Moscou et al.   SCIENCE

Activity and Specificity of the Bacterial PD-(D/E)XK Homing Endonuclease I-Ssp6803I

(2008) Lei Zhao et al.   JOURNAL OF MOLECULAR BIOLOGY

Characterization of AvrHah1, a novel AvrBs3-like effector fromXanthomonas gardneriwith virulence and avirulence activity

(2008) Sebastian Schornack et al.   NEW PHYTOLOGIST