DNA editing in DNA/RNA hybrids by adenosine deaminases that act on RNA

CRISPR/Cas9 in Genome Editing and Beyond

(2016) Haifeng Wang et al.   Annual Review of Biochemistry

Genetic spectrum of dyschromatosis symmetrica hereditaria in Chinese patients including a novel nonstop mutation in ADAR1 gene

(2016) Guolong Zhang et al.   BMC Medical Genetics

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage

(2016) Alexis C. Komor et al.   NATURE

Structures of human ADAR2 bound to dsRNA reveal base-flipping mechanism and basis for site selectivity

(2016) Melissa M Matthews et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Neurologic Phenotypes Associated with Mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, ADAR1, and IFIH1: Aicardi–Goutières Syndrome and Beyond

(2016) Yanick Crow et al.   NEUROPEDIATRICS

Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems

(2016) K. Nishida et al.   SCIENCE

Structures of human ADAR2 bound to dsRNA reveal base-flipping mechanism and basis for site selectivity

(2016) Melissa M Matthews et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A Phenotypic Screen for Functional Mutants of Human Adenosine Deaminase Acting on RNA 1

(2015) Yuru Wang et al.   ACS Chemical Biology

Crystal structure of RNA-DNA duplex provides insight into conformational changes induced by RNase H binding

(2015) Ryan R Davis et al.   CELL CYCLE

Recognition of duplex RNA by the deaminase domain of the RNA editing enzyme ADAR2

(2015) Kelly J. Phelps et al.   NUCLEIC ACIDS RESEARCH

RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself

(2015) B. J. Liddicoat et al.   SCIENCE

Genome-wide DNA hypomethylation and RNA:DNA hybrid accumulation in Aicardi–Goutières syndrome

(2015) Yoong Wearn Lim et al.   eLife

Click Modification of RNA at Adenosine: Structure and Reactivity of 7-Ethynyl- and 7-Triazolyl-8-aza-7-deazaadenosine in RNA

(2014) Kelly J. Phelps et al.   ACS Chemical Biology

Substrate Recognition and Specificity of Double-Stranded RNA Binding Proteins

(2014) Lela Vuković et al.   BIOCHEMISTRY

Arginine Methylation Facilitates the Recruitment of TOP3B to Chromatin to Prevent R Loop Accumulation

(2014) Yanzhong Yang et al.   MOLECULAR CELL

The new frontier of genome engineering with CRISPR-Cas9

(2014) J. A. Doudna et al.   SCIENCE

The RNA-Editing Enzyme ADAR1 Controls Innate Immune Responses to RNA

(2014) Niamh M. Mannion et al.   Cell Reports

RNA-Seq Analysis Identifies a Novel Set of Editing Substrates for Human ADAR2 Present in Saccharomyces cerevisiae

(2013) Tristan Eifler et al.   BIOCHEMISTRY

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

ADAR1 regulates ARHGAP26 gene expression through RNA editing by disrupting miR-30b-3p and miR-573 binding

(2013) Q. Wang et al.   RNA

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

Adenosine-to-inosine RNA editing and human disease

(2013) William Slotkin et al.   Genome Medicine

ADAR1 Protein Induces Adenosine-targeted DNA Mutations in Senescent Bcl6 Gene-deficient Cells

(2012) Nobuhide Tsuruoka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human endonuclease V as a repair enzyme for DNA deamination

(2012) Rongjuan Mi et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature

(2012) Gillian I Rice et al.   NATURE GENETICS

Nucleoside analog studies indicate mechanistic differences between RNA-editing adenosine deaminases

(2012) Rena A. Mizrahi et al.   NUCLEIC ACIDS RESEARCH

Mechanistic insights into editing-site specificity of ADARs

(2012) A. Kuttan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Predicting sites of ADAR editing in double-stranded RNA

(2011) Julie M. Eggington et al.   Nature Communications

Functions and Regulation of RNA Editing by ADAR Deaminases

(2010) Kazuko Nishikura   Annual Review of Biochemistry

Endonuclease V-mediated deoxyinosine excision repair in vitro

(2010) Chia-Chia Lee et al.   DNA REPAIR

RNA editing changes the lesion specificity for the DNA repair enzyme NEIL1

(2010) J. Yeo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-Wide Identification of Human RNA Editing Sites by Parallel DNA Capturing and Sequencing

(2009) J. B. Li et al.   SCIENCE