Monitoring Replication Protein A (RPA) dynamics in homologous recombination through site-specific incorporation of non-canonical amino acids

Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1

(2017) Hai Dang Nguyen et al.   MOLECULAR CELL

RPA binds histone H3-H4 and functions in DNA replication–coupled nucleosome assembly

(2017) Shaofeng Liu et al.   SCIENCE

Dynamic binding of replication protein a is required for DNA repair

(2016) Ran Chen et al.   NUCLEIC ACIDS RESEARCH

Protein dynamics of human RPA and RAD51 on ssDNA during assembly and disassembly of the RAD51 filament

(2016) Chu Jian Ma et al.   NUCLEIC ACIDS RESEARCH

Rad51 Nucleoprotein Filament Disassembly Captured Using Fluorescent Plasmodium falciparum SSB as a Reporter for Single-Stranded DNA

(2016) Eric Parker Davenport et al.   PLoS One

A general approach to visualize protein binding and DNA conformation without protein labelling

(2016) Dan Song et al.   Nature Communications

A rapid method for detecting protein-nucleic acid interactions by protein induced fluorescence enhancement

(2016) Sona Valuchova et al.   Scientific Reports

How cancer cells hijack DNA double-strand break repair pathways to gain genomic instability

(2015) P. A. Jeggo et al.   BIOCHEMICAL JOURNAL

Rad51 Paralogs Remodel Pre-synaptic Rad51 Filaments to Stimulate Homologous Recombination

(2015) Martin R.G. Taylor et al.   CELL

Ideal Bioorthogonal Reactions Using A Site-Specifically Encoded Tetrazine Amino Acid

(2015) Robert J. Blizzard et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Characteristics and concepts of dynamic hub proteins in DNA processing machinery from studies of RPA

(2015) Norie Sugitani et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Site Specific Genetic Incorporation of Azidophenylalanine in Schizosaccharomyces pombe

(2015) Nan Shao et al.   Scientific Reports

Replication protein A: Single-stranded DNA's first responder

(2014) Ran Chen et al.   BIOESSAYS

Context-Dependent Remodeling of Rad51–DNA Complexes by Srs2 Is Mediated by a Specific Protein–Protein Interaction

(2014) Anna K. Lytle et al.   JOURNAL OF MOLECULAR BIOLOGY

Diffusion of Human Replication Protein A along Single-Stranded DNA

(2014) Binh Nguyen et al.   JOURNAL OF MOLECULAR BIOLOGY

Protein dynamics during presynaptic-complex assembly on individual single-stranded DNA molecules

(2014) Bryan Gibb et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Concentration-Dependent Exchange of Replication Protein A on Single-Stranded DNA Revealed by Single-Molecule Imaging

(2014) Bryan Gibb et al.   PLoS One

Regulation of DNA Pairing in Homologous Recombination

(2014) J. M. Daley et al.   Cold Spring Harbor Perspectives in Biology

How do proteins locate specific targets in DNA?

(2013) Sy Redding et al.   CHEMICAL PHYSICS LETTERS

Protein induced fluorescence enhancement (PIFE) for probing protein–nucleic acid interactions

(2013) Helen Hwang et al.   CHEMICAL SOCIETY REVIEWS

A Genetically Encoded Fluorescent Probe in Mammalian Cells

(2013) Abhishek Chatterjee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure and conformational change of a replication protein A heterotrimer bound to ssDNA

(2012) J. Fan et al.   GENES & DEVELOPMENT

Asymmetric Regulation of Bipolar Single-stranded DNA Translocation by the Two Motors withinEscherichia coliRecBCD Helicase

(2012) Fuqian Xie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Single-Stranded DNA Translocation of E. coli UvrD Monomer Is Tightly Coupled to ATP Hydrolysis

(2012) Eric J. Tomko et al.   JOURNAL OF MOLECULAR BIOLOGY

Performance Analysis of Orthogonal Pairs Designed for an Expanded Eukaryotic Genetic Code

(2012) Sebastian Nehring et al.   PLoS One

Single-molecule imaging reveals target-search mechanisms during DNA mismatch repair

(2012) J. Gorman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Repair-specific Functions of Replication Protein A

(2011) Cathy S. Hass et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Real-Time Observation of Strand Exchange Reaction with High Spatiotemporal Resolution

(2011) Kaushik Ragunathan et al.   STRUCTURE

Adding New Chemistries to the Genetic Code

(2010) Chang C. Liu et al.   Annual Review of Biochemistry

Binding of the DimericDeinococcus radioduransSingle-Stranded DNA Binding Protein to Single-Stranded DNA

(2010) Alexander G. Kozlov et al.   BIOCHEMISTRY

Beyond the Canonical 20 Amino Acids: Expanding the Genetic Lexicon

(2010) Travis S. Young et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Single-stranded DNA Binding by the C Termini of Escherichia coli Single-stranded DNA-binding (SSB) Protein

(2010) Alexander G. Kozlov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MALDI−TOF Mass Spectral Characterization of Polymers Containing an Azide Group: Evidence of Metastable Ions

(2010) Yejia Li et al.   MACROMOLECULES

Ensemble methods for monitoring enzyme translocation along single stranded nucleic acids

(2010) Eric J. Tomko et al.   METHODS

Escherichia coli RecBC helicase has two translocase activities controlled by a single ATPase motor

(2010) Colin G Wu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Probing Protein Folding Using Site-Specifically Encoded Unnatural Amino Acids as FRET Donors with Tryptophan

(2009) Shigeki J. Miyake-Stoner et al.   BIOCHEMISTRY

Regulation of Rad51 Recombinase Presynaptic Filament Assembly via Interactions with the Rad52 Mediator and the Srs2 Anti-recombinase

(2009) Changhyun Seong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic Incorporation of a Small, Environmentally Sensitive, Fluorescent Probe into Proteins inSaccharomyces cerevisiae

(2009) Hyun Soo Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Srs2 Disassembles Rad51 Filaments by a Protein-Protein Interaction Triggering ATP Turnover and Dissociation of Rad51 from DNA

(2009) Edwin Antony et al.   MOLECULAR CELL

SSB protein diffusion on single-stranded DNA stimulates RecA filament formation

(2009) Rahul Roy et al.   NATURE

Essential functions of the 32 kDa subunit of yeast replication protein A

(2009) Anne M. Dickson et al.   NUCLEIC ACIDS RESEARCH

Nucleases and helicases take center stage in homologous recombination

(2009) Eleni P. Mimitou et al.   TRENDS IN BIOCHEMICAL SCIENCES