Nuclear receptor 4A1 as a drug target for breast cancer chemotherapy

Nuclear Receptor 4A1 (NR4A1) as a Drug Target for Renal Cell Adenocarcinoma

(2015) Erik Hedrick et al.   PLoS One

Targeting the PI3K/AKT/mTOR pathway in estrogen receptor-positive breast cancer

(2014) Eva Maria Ciruelos Gil   CANCER TREATMENT REVIEWS

The Orphan Nuclear Receptor NR4A1 (Nur77) Regulates Oxidative and Endoplasmic Reticulum Stress in Pancreatic Cancer Cells

(2014) Syng-Ook Lee et al.   MOLECULAR CANCER RESEARCH

Diindolylmethane Analogs Bind NR4A1 and Are NR4A1 Antagonists in Colon Cancer Cells

(2014) Syng-Ook Lee et al.   MOLECULAR ENDOCRINOLOGY

Nuclear receptor NR4A1 promotes breast cancer invasion and metastasis by activating TGF-β signalling

(2014) FangFang Zhou et al.   Nature Communications

Investigating a pathogenic role for TXNDC5 in tumors

(2013) XIAOTIAN CHANG et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Research Resource: Nuclear Receptors as Transcriptome: Discriminant and Prognostic Value in Breast Cancer

(2013) George E. O. Muscat et al.   MOLECULAR ENDOCRINOLOGY

Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway

(2013) Wei-jia Wang et al.   Nature Chemical Biology

The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK

(2012) Yan-yan Zhan et al.   Nature Chemical Biology

Targeting NR4A1 (TR3) in cancer cells and tumors

(2011) Syng-Ook Lee et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Everolimus in Postmenopausal Hormone-Receptor–Positive Advanced Breast Cancer

(2011) José Baselga et al.   NEW ENGLAND JOURNAL OF MEDICINE

The nuclear receptor TR3 regulates mTORC1 signaling in lung cancer cells expressing wild-type p53

(2011) S-O Lee et al.   ONCOGENE

Inactivation of the Orphan Nuclear Receptor TR3/Nur77 Inhibits Pancreatic Cancer Cell and Tumor Growth

(2010) S.-O. Lee et al.   CANCER RESEARCH

A Unique Pharmacophore for Activation of the Nuclear Orphan Receptor Nur77 In vivo and In vitro

(2010) Jing-jing Liu et al.   CANCER RESEARCH

Regulation of Nur77 expression by β-catenin and its mitogenic effect in colon cancer cells

(2010) Hua Wu et al.   FASEB JOURNAL

Differential proteomic analysis of a highly metastatic variant of human breast cancer cells using two-dimensional differential gel electrophoresis

(2010) Si-Guang Xu et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Minireview: Nuclear Hormone Receptor 4A Signaling: Implications for Metabolic Disease

(2010) Michael A. Pearen et al.   MOLECULAR ENDOCRINOLOGY

Paclitaxel Directly Binds to Bcl-2 and Functionally Mimics Activity of Nur77

(2009) C. Ferlini et al.   CANCER RESEARCH

p21 Expression Is Induced by Activation of Nuclear Nerve Growth Factor-Induced B  (Nur77) in Pancreatic Cancer Cells

(2009) S.-O. Lee et al.   MOLECULAR CANCER RESEARCH

Activation of Nerve Growth Factor-Induced B  by Methylene-Substituted Diindolylmethanes in Bladder Cancer Cells Induces Apoptosis and Inhibits Tumor Growth

(2009) S. Dae Cho et al.   MOLECULAR PHARMACOLOGY

A Short Nur77-Derived Peptide Converts Bcl-2 from a Protector to a Killer

(2008) Siva Kumar Kolluri et al.   CANCER CELL

Cytosporone B is an agonist for nuclear orphan receptor Nur77

(2008) Yanyan Zhan et al.   Nature Chemical Biology