Article
Chemistry, Multidisciplinary
Xiaoqing Wei, Dan Mu, Yingping Li, Jingya Zhao, Shaobing Zhou
Summary: Researchers have developed a magnetic exosome that responds to bacteria associated with tumors, enabling sensitive tumor imaging. The magnetic exosome can rapidly respond in the tumor microenvironment and release iron oxide nanoparticles for dynamic MRI of tumors. After MRI, the iron oxide nanoparticles can be eliminated through renal clearance to avoid potential toxicity.
Article
Materials Science, Multidisciplinary
Yiwei Zhang, Xinxin Li, Xing Chen, Yingfan Zhang, Yun Deng, Yanhua Yu, Bing Wang, Yanan Xue, Yulun Huang, Min Liu
Summary: In this study, a 0-cyclodextrin-modified ultrasmall gold nanoparticle was prepared as a functional core, and contrast agents and folate were anchored on its surface to give it the ability to target tumor cells. Compared to clinical contrast agents, this nanocomposite exhibited higher longitudinal relaxivity and excellent biocompatibility. In vivo studies showed that it could accumulate in the tumor region and acquire high-resolution MRI images.
MATERIALS & DESIGN
(2022)
Article
Nanoscience & Nanotechnology
Li-Hua Deng, Hai Jiang, Fu-Lin Lu, Han-Wei Wang, Yu Pu, Chang-Qiang Wu, Hong-Jie Tang, Ye Xu, Tian-Wu Chen, Jiang Zhu, Cheng-Yi Shen, Xiao-Ming Zhang
Summary: By using PEGylated SPIO nanoparticles as MRI contrast agents, different nanocrystal sizes and PEG coatings can be utilized to achieve T-1, T-2, or T-1-T-2 dual-mode imaging at different magnetic field intensities.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2021)
Article
Biochemistry & Molecular Biology
Paolo Arosio, Davide Cicolari, Amedea Manfredi, Francesco Orsini, Alessandro Lascialfari, Elisabetta Ranucci, Paolo Ferruti, Daniela Maggioni
Summary: In this study, a linear polyamidoamine (PAA) named BAC-EDDS was successfully synthesized and showed stable nanoaggregates with negative charge, demonstrating good performance as a contrast agent in magnetic resonance imaging.
Article
Materials Science, Multidisciplinary
Yaning Zhao, Congcong Cui, Jiahui Zhan, Guangshan Xuan
Summary: The study successfully prepared folate-chitosan/chitosan-diethylenetriaminepentaacetic acid-gadolinium nanoparticles, which exhibited good magnetic properties and specific targeting effect towards folate-overexpressing tumor cells.
MATERIALS TODAY COMMUNICATIONS
(2022)
Article
Chemistry, Applied
Chen Zhou, Hai-Yong Ao, Xiao Han, Wen-Wen Jiang, Zhi-Fei Yang, Le Ma, Xiao-Yan Deng, Yi-Zao Wan
Summary: PA-g-HACC is an antibacterial agent with broad-spectrum antibacterial properties and pharmacological activities, showing antibacterial rates above 92% against Staphylococcus aureus and methicillin-resistant Staphylococcus aureus, and increased antibacterial rate against E. coli with the amount of grafted PA. The cytocompatibility of PA-g-HACC can be improved by appropriate grafting ratio of PA, while excessive grafted PA may lead to toxicity.
CARBOHYDRATE POLYMERS
(2021)
Article
Nanoscience & Nanotechnology
Yongjie Xiong, Yi Qu, Zhe Min, Jun Wu, Suming Zhang, Zheng Xue
Summary: This study developed a novel MRI contrast agent by coupling ultrasmall superparamagnetic iron oxide nanoparticles with a functional protein. The contrast agent successfully penetrated biological membranes and bound to Aβ deposits, allowing for the visualization of Aβ deposits in Alzheimer's disease animal models by MRI.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2022)
Article
Chemistry, Multidisciplinary
Kholoud K. Arafa, Mohamed A. Hamzawy, Shaker A. Mousa, Ibrahim M. El-Sherbiny
Summary: This study presents the rational designing of mitochondria-targeted core-shell polymeric nanoparticles for efficient delivery of doxorubicin to hepatic carcinoma mitochondria, showing promising results in inducing apoptotic cell death and cell cycle arrest.
Article
Pharmacology & Pharmacy
Asmaa M. Elfiky, Rania Hassan Mohamed, Fatma El-Zahraa Abd EL-Hakam, Mohamed A. Yassin, Mahmoud ElHefnawi
Summary: This study demonstrated the potential of LA-PAMAM carrier for targeted delivery of tumor suppressor miR-218 as a therapeutic candidate for HCC. The combination of hyperbranched polyamidoamine and lactobionic acid efficiently suppressed HepG2 cell proliferation and down-regulated the oncogenic HOXA1 target.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2021)
Article
Materials Science, Multidisciplinary
A. M. Panich, A. Shames, A. E. Aleksenskii, E. B. Yudina, A. Ya Vul'
Summary: In this study, a novel nanomaterial called detonation nanodiamond (DND) with manganese ions grafted to its surface was successfully prepared and investigated for its potential as an MRI contrast agent. The chemical binding of Mn2+ ions to the nanodiamond surface was confirmed, with interactions accelerating spin-lattice relaxation. Comparison with Gd-grafted DND suggests that Mn-DND has promising applications in MRI contrast imaging.
DIAMOND AND RELATED MATERIALS
(2021)
Article
Biotechnology & Applied Microbiology
Li Xu, Zhanying Ren, Guolin Li, Danni Xu, Jiaqian Miao, Jingxuan Ju, Xuan Mo, Xianghui Wang, Hongping Deng, Min Xu
Summary: A liver-targeting gadolinium-based MRI contrast agent was developed using galactose functionalized o-carboxymethyl chitosan, which exhibited higher hepatocyte uptake, excellent biocompatibility, and better T1-weighted signal enhancement in the liver. The agent showed good safety in vivo at a specific dose.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Nanoscience & Nanotechnology
Rong Tu, Xiaoguang You, Zhichao Ding, Huanyu Wu, Linlu Zhao, Zhi Qiu, Junjie Wei, Xiaofeng Yang
Summary: The development of imaging methods that can detect target molecules is of great importance for non-invasive molecular diagnosis. In this study, a magnetic resonance contrast agent was created by coupling a polypeptide with a Gd(DOTA) complex, which is capable of binding to the target molecule. The results showed that this contrast agent exhibited high targeting ability and image enhancement.
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Muhammad Waqas, Anum Shahzadi, Ali Haider, Anwar Ul Hamid, Mohammed M. Algaradah, Hisham S. M. Abd-Rabboh, Muhammad Ikram
Summary: In this study, MnO2 nanorods and CS-g-PAA doped MnO2 were prepared hydrothermally to enhance the dye degradation efficiency and antimicrobial activity. The analysis of the properties of MnO2 after doping showed an increase in crystallite size and a change in morphology. PL spectroscopy confirmed the decrease in electron-hole pair recombination rate, indicating the enhanced catalytic activity. CS-g-PAA doped MnO2 exhibited high antimicrobial efficiency against E. coli.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Medicine, Research & Experimental
Haihan Sun, Kun Shi, Bangjie Zuo, Xin Zhang, Yue Liu, Dong Sun, Fengzhen Wang
Summary: This study demonstrates the potential application of metformin-grafted chitosan nanoparticles in kidney-targeted therapy, which can enhance the anti-fibrotic effect of metformin.
MOLECULAR PHARMACEUTICS
(2022)
Article
Chemistry, Multidisciplinary
Qing Xu, Feng Jiang, Geyong Guo, Endian Wang, Muhammad Rizwan Younis, Zhaowenbin Zhang, Feiyang Zhang, Zhiguang Huan, Chen Fan, Chen Yang, Hao Shen, Jiang Chang
Summary: This study developed multifunctional nanoparticles for combating drug-resistant bacteria and repairing infectious tissue. These nanoparticles showed high-efficiency, quick, and long-term antibacterial effects through near-infrared light-induced heating and copper ion release, as well as immune response promotion and stimulation of angiogenesis.
Article
Chemistry, Multidisciplinary
Zihan Ma, Lishuang Wang, Tingting Chen, Guangning Wang
Summary: In this study, two kinds of 3D self-doped (N/O) lilac-based and coriander-based porous carbons with high performance have been prepared.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Qin Wang, Yun-Fan Yan, Jiao-Lin Weng, Ying Huang, Fu Yang, Hao-Hui Xie, Fei Tan, Fa-Kun Zheng, Jian-Gang Xu
Summary: Balancing energy and mechanical sensitivities is a challenging issue in the field of energetic materials. This study constructed a 3D energetic metal-organic framework with nitrogen-rich ligand and NO3- anions. The framework demonstrated high stability, energy density, and excellent mechanical sensitivities, making it a potential insensitive energetic material.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Marrium Saeed, Urooj Kamran, Amina Khan, Md Irfanul Haque Siddiqui, Hasan Jamal, Haq Nawaz Bhatti
Summary: In this study, magnesium-aluminum layered double hydroxides (Mg-Al-LDH) were synthesized using an environmentally friendly hydrothermal technique for adsorbing the dye reactive green 5 (RG5). To improve the adsorption capability, composites were prepared by combining Mg-Al-LDH with low-cost Mangifera indica stone biomass (MISB). The results showed that the composites had high adsorption capacities for RG5 dye and could be regenerated.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Xuanlin Zhan, Xiaojie Li, Yunyan Zeng, Siyan Jiang, Chao Pan, Shiyu Pan, Jiaquan Huang, Heqian Zhang, Zhiwei Qin
Summary: This study reports on the potential prospects of natural products derived from the rhizosphere for the development of antibiotics and herbicides, as well as the advancements in cultivating a mutant strain that produces a substantial quantity of lydicamycins, a potent family for herbicide development.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Jie Zhu, Jiangtao Yu, Linhua Zhu, Xiaoxiao Yu, Jixing Liu, Yanhong Chao, Jingzhou Yin, Peiwen Wu, Jian Liu, Wenshuai Zhu
Summary: This study successfully demonstrates the 3D printing of attapulgite monoliths and investigates the influence of thermal treatment on their properties. The thermal treated monoliths show superior catalytic performance at low temperatures.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Yanzhu Ye, Yixiang Ye, Jiannan Cai, Zhongshui Li, Shen Lin
Summary: In this paper, a novel Pt/CoP/C photo-electro synergistic catalyst was successfully synthesized and its performance was investigated. The catalyst exhibited excellent photo-electro catalytic performance, with significantly higher hydrogen production compared to a commercial catalyst. The introduction of cobalt phosphide and the existence of Co3O4 were identified as key factors for enhancing the catalytic activity.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Nurul Hidayah Abu Bakar, Wan Norfazilah Wan Ismail, Hartina Mohd Yusop, Noreen Farzuhana Mohd Zulkifli
Summary: Hydrophobic coatings inspired by the lotus effect have gained popularity for their ability to solve various problems. The sol-gel method, utilizing silica, alumina, and titania, is explored as an environmentally friendly approach to produce water-based hydrophobic coatings. This study focuses on producing water-based hydrophobic coatings for cotton and polyester fabrics using a one-step sol-gel method. The coated fabrics exhibited improved hydrophobic properties, altered surface morphologies, and lower air permeability compared to uncoated fabrics. TEOS-PDMS coating provides a promising approach for enhancing the hydrophobic and surface properties of cotton and polyester fabrics.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Nikita Belko, Hanna Maltanava, Anatol Lugovski, Polina Shabunya, Sviatlana Fatykhava, Evgeny Bondarenko, Pavel Chulkin, Sergey Poznyak, Michael Samtsov
Summary: This study investigates the difference in electrochemical behavior between rhodamine B hydrazide and rhodamine B acylhydrazone, and finds that rhodamine B acylhydrazone exhibits higher reversibility in electrooxidation. These results can be applied for developing new sensors with desired electrochemical properties.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Showket Ahmad Bhat, Mohd Ikram
Summary: In this study, 0-3 particulate multiferroic composites were synthesized and characterized. The composites exhibited excellent ferroelectric and ferromagnetic properties, as well as high piezoelectric strain and magnetoelectric coupling effects.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Carla Gomes, Mariana Costa, Susana M. M. Lopes, Bernardo Albuquerque Nogueira, Rui Fausto, Jose A. Paixao, Teresa M. V. D. e Melo, Luisa M. D. R. S. Martins, Marta Pineiro
Summary: The development of sustainable processes requires the integration of green chemistry principles. In this study, a solvent-free synthesis method was developed to prepare new copper catalysts, which efficiently catalyze cycloaddition reactions under solvent-free mechanochemical conditions. Through this process, the principles of atom economy, reduction of solvents and auxiliaries, design for energy efficiency, and reduction of derivatives and catalysis are combined.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Zhihua Liu, Jinzhe Li, Jianguo Zhou
Summary: This study demonstrates the enhancement of photoelectrochemical activity of BiFeO3 photoelectrodes through ion modification, which increases visible light absorption and active area, leading to improved PEC water splitting performance.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Yisheng Zhang, Wensong Li, Jing Li, Fang Li, Wei Xue, Xinqiang Zhao, Yanji Wang
Summary: Pt/C and SO42-/ZrO2 were used as catalysts for the synthesis of p-aminophenol through the catalytic transfer hydrogenation of nitrobenzene in water with formic acid as the hydrogen source. The optimal Pt loading for PAP selectivity was found to be 1 wt%. The presence of different valence states of Pt affected both the nitrobenzene hydrogenation and formic acid decomposition. Among different solid acid catalysts tested, SO42-/ZrO2 exhibited the highest catalytic activity for p-aminophenol formation. Under the optimized reaction conditions, the conversion of nitrobenzene reached 80.0%, with a selectivity of 47.6% for p-aminophenol.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Pradyota Kumar Behera, Papita Behera, Amlan Swain, Santosh Kumar Sahu, Ajeena Sahoo, Laxmidhar Rout
Summary: We have developed a simple and direct method for the synthesis of diaryl ether using an oxygen bridged bimetallic CuMoO4 nanocatalyst under mild reaction conditions. The catalyst exhibited tolerance towards a wide range of substrates with various functional groups. It is efficient and recyclable. This methodology allows easy access to nitrofen derivatives (herbicides) from unactivated 2,4-dichlorophenol, which are important for agriculture and pharmaceuticals.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Yihua Fu, Yan Zhang, Changwei Hu, Zhishan Su
Summary: The mechanism of the reaction between CO2 and styrene oxide for cyclic carbonate was revealed using density functional theory calculations. The noncatalytic reaction occurred via a concerted mechanism, while in the presence of guanidine and tetrabutylammonium iodide (TBAI) co-catalysts, the epoxide ring-opening by nucleophilic attack of an iodide anion was predicted to be the rate-determining step. Guanidine acted as the H-bond donor to activate styrene oxide, facilitating the reaction with a lower activation barrier.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Saikat Khamarui, Sirshendu Ghosh
Summary: Copper nanorods (Cu-NRs) exhibit significant plasmonic behavior and can act as efficient catalysts in redox processes and coupling. A benign decarboxylative approach, utilizing localized surface plasmon resonance (LSPR) assisted catalysis with Cu-NRs, has been developed for the production of alkane analogues from alkyl carboxylic acids under visible light. The catalyst shows a broad substrate scope and high functional group tolerance, without the need for an external oxidant or proton source. A plausible mechanism for this recyclable nano-catalyst has also been proposed based on control experiments.
NEW JOURNAL OF CHEMISTRY
(2024)