Early-Life Social Isolation-Induced Depressive-Like Behavior in Rats Results in Microglial Activation and Neuronal Histone Methylation that Are Mitigated by Minocycline

Duloxetine prevents the effects of prenatal stress on depressive-like and anxiety-like behavior and hippocampal expression of pro-inflammatory cytokines in adult male offspring rats

(2016) Xiaosong Zhang et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Integrating neuroimmune systems in the neurobiology of depression

(2016) Eric S. Wohleb et al.   NATURE REVIEWS NEUROSCIENCE

Blockade of NMDA receptors reverses the depressant, but not anxiogenic effect of adolescence social isolation in mice

(2015) Arya Haj-Mirzaian et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

SET7/9 Enzyme Regulates Cytokine-induced Expression of Inducible Nitric-oxide Synthase through Methylation of Lysine 4 at Histone 3 in the Islet β Cell

(2015) Kyoko Fujimaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microglia-Dependent Alteration of Glutamatergic Synaptic Transmission and Plasticity in the Hippocampus during Peripheral Inflammation

(2015) K. Riazi et al.   JOURNAL OF NEUROSCIENCE

Insulin-like growth factor 2 mitigates depressive behavior in a rat model of chronic stress

(2015) Yan-Wei Luo et al.   NEUROPHARMACOLOGY

The role of inflammation and microglial activation in the pathophysiology of psychiatric disorders

(2015) G.Z. Réus et al.   NEUROSCIENCE

Depression as a Microglial Disease

(2015) Raz Yirmiya et al.   TRENDS IN NEUROSCIENCES

Phenotypic dysregulation of microglial activation in young offspring rats with maternal sleep deprivation-induced cognitive impairment

(2015) Qiuying Zhao et al.   Scientific Reports

Broken or maladaptive? Altered trajectories in neuroinflammation and behavior after early life adversity

(2015) Prabarna Ganguly et al.   Developmental Cognitive Neuroscience

Early enriched environment induces an increased conversion of proBDNF to BDNF in the adult rat's hippocampus

(2014) Wenyu Cao et al.   BEHAVIOURAL BRAIN RESEARCH

Insights from interferon-α-related depression for the pathogenesis of depression associated with inflammation

(2014) Carolina Hoyo-Becerra et al.   BRAIN BEHAVIOR AND IMMUNITY

Development of Anxiety-Like Behavior via Hippocampal IGF-2 Signaling in the Offspring of Parental Morphine Exposure: Effect of Enriched Environment

(2014) Chang-Qi Li et al.   NEUROPSYCHOPHARMACOLOGY

Autoantibodies and depression

(2014) Rosebella Alungata Iseme et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Microglial Dysregulation in Psychiatric Disease

(2013) Luciana Romina Frick et al.   Clinical & Developmental Immunology

Short-term social isolation induces depressive-like behaviour and reinstates the retrieval of an aversive task: Mood-congruent memory in male mice?

(2013) André Takatsu-Coleman   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Dynamic microglial alterations underlie stress-induced depressive-like behavior and suppressed neurogenesis

(2013) T Kreisel et al.   MOLECULAR PSYCHIATRY

The Action of Antidepressants on the Glutamate System: Regulation of Glutamate Release and Glutamate Receptors

(2012) Laura Musazzi et al.   BIOLOGICAL PSYCHIATRY

Anterior cingulate cortical lesion attenuates food foraging in rats

(2012) Fang Li et al.   BRAIN RESEARCH BULLETIN

The immune theory of psychiatric diseases: a key role for activated microglia and circulating monocytes

(2012) Wouter Beumer et al.   JOURNAL OF LEUKOCYTE BIOLOGY

L-glutamate released from activated microglia downregulates astrocytic L-glutamate transporter expression in neuroinflammation: the ‘collusion’ hypothesis for increased extracellular L-glutamate concentration in neuroinflammation

(2012) Junpei Takaki et al.   Journal of Neuroinflammation

Neural Mechanisms of Stress Resilience and Vulnerability

(2012) Tamara B. Franklin et al.   NEURON

Histone Regulation in the CNS: Basic Principles of Epigenetic Plasticity

(2012) Ian Maze et al.   NEUROPSYCHOPHARMACOLOGY

Microglia: actively surveying and shaping neuronal circuit structure and function

(2012) Hiroaki Wake et al.   TRENDS IN NEUROSCIENCES

Evidence that Microglia Mediate the Neurobiological Effects of Chronic Psychological Stress on the Medial Prefrontal Cortex

(2011) M. Hinwood et al.   CEREBRAL CORTEX

Histone H3K9 modifications are a local chromatin event involved in ethanol-induced neuroadaptation of the NR2B gene

(2011) Mei Qiang et al.   Epigenetics

Hyperphagia and depression-like behavior by adolescence social isolation in female rats

(2011) Jeong Won Jahng et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

The Role of Microglia in the Healthy Brain

(2011) M.-E. Tremblay et al.   JOURNAL OF NEUROSCIENCE

A Role for Repressive Histone Methylation in Cocaine-Induced Vulnerability to Stress

(2011) Herbert E. Covington et al.   NEURON

Towards a glutamate hypothesis of depression

(2011) Gerard Sanacora et al.   NEUROPHARMACOLOGY

Physiology of Microglia

(2011) Helmut Kettenmann et al.   PHYSIOLOGICAL REVIEWS

Balancing histone methylation activities in psychiatric disorders

(2011) Cyril Jayakumar Peter et al.   TRENDS IN MOLECULAR MEDICINE

Integrated Brain Circuits: Astrocytic Networks Modulate Neuronal Activity and Behavior

(2010) Michael M. Halassa et al.   Annual Review of Physiology

Understanding the role of inflammatory-related pathways in the pathophysiology and treatment of psychiatric disorders: evidence from human peripheral studies and CNS studies

(2010) Brian Dean   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Histone Methylation Regulates Memory Formation

(2010) S. Gupta et al.   JOURNAL OF NEUROSCIENCE

Brain function and chromatin plasticity

(2010) Catherine Dulac   NATURE

Essential Role of the Histone Methyltransferase G9a in Cocaine-Induced Plasticity

(2010) I. Maze et al.   SCIENCE

Limbic Regulation of Hypothalamo-Pituitary-Adrenocortical Function during Acute and Chronic Stress

(2009) Ryan Jankord et al.   Annals of the New York Academy of Sciences

Emerging role of glutamate in the pathophysiology of major depressive disorder

(2009) Kenji Hashimoto   BRAIN RESEARCH REVIEWS

Antidepressant Actions of Histone Deacetylase Inhibitors

(2009) H. E. Covington et al.   JOURNAL OF NEUROSCIENCE

Control of Cognition and Adaptive Behavior by the GLP/G9a Epigenetic Suppressor Complex

(2009) Anne Schaefer et al.   NEURON

Isolation rearing induces social and emotional function abnormalities and alters glutamate and neurodevelopment-related gene expression in rats

(2009) Xiaohong Zhao et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Early-life programming of later-life brain and behavior: a critical role for the immune system

(2009) Staci D. Bilbo   Frontiers in Behavioral Neuroscience

Minocycline and neurodegenerative diseases

(2008) Hye-Sun Kim et al.   BEHAVIOURAL BRAIN RESEARCH

Does minocycline have antidepressant effect?

(2008) Chi-Un Pae et al.   BIOMEDICINE & PHARMACOTHERAPY

Stress load during childhood affects psychopathology in psychiatric patients

(2008) Katja Weber et al.   BMC Psychiatry

AMPA receptor subunit 1 (GluR-A) knockout mice model the glutamate hypothesis of depression

(2008) S. Chourbaji et al.   FASEB JOURNAL

Interleukin-1 (IL-1): A central regulator of stress responses

(2008) Inbal Goshen et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Japanese Encephalitis Virus infection induces IL-18 and IL-1β in microglia and astrocytes: Correlation with in vitro cytokine responsiveness of glial cells and subsequent neuronal death

(2008) Sulagna Das et al.   JOURNAL OF NEUROIMMUNOLOGY

The inflammatory & neurodegenerative (I&ND) hypothesis of depression: leads for future research and new drug developments in depression

(2008) Michael Maes et al.   METABOLIC BRAIN DISEASE

The CRF System Mediates Increased Passive Stress-Coping Behavior Following the Loss of a Bonded Partner in a Monogamous Rodent

(2008) Oliver J Bosch et al.   NEUROPSYCHOPHARMACOLOGY

Behavioural and neurochemical effects of post-weaning social isolation in rodents—Relevance to developmental neuropsychiatric disorders

(2008) Kevin C.F. Fone et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS