Article
Integrative & Complementary Medicine
Bengu Cetinkaya
Summary: The study evaluated the efficacy and safety of complementary and alternative therapy methods for infantile colic, finding that acupuncture, aromatherapy, and massage were effective in reducing symptoms with no serious side effects reported. Further research is needed to provide more evidence for their use in treating infantile colic.
ALTERNATIVE THERAPIES IN HEALTH AND MEDICINE
(2021)
Review
Pediatrics
Sara Cabanillas-Barea, Sandra Jimenez-del-Barrio, Andoni Carrasco-Uribarren, Anna Ortega-Martinez, Silvia Perez-Guillen, Luis Ceballos-Laita
Summary: The aim of this study was to evaluate the effectiveness of osteopathy and chiropractic techniques in reducing crying time and increasing sleeping time in babies with infantile colic. However, the results of the systematic review and meta-analysis showed that these complementary treatments failed to achieve the desired outcomes.
Article
Integrative & Complementary Medicine
Yuezhen Lin, Ling Wu, Ruihua Zhao, Pui Wah Chung, Chi Chiu Wang
Summary: Current medical treatments for endometriosis-associated pain have limitations, and Chinese herbal medicine (CHM) shows potential as an alternative or complementary treatment. This study analyzed randomized control trials comparing CHM to other treatments for endometriosis-associated pain, and found that CHM, used alone or in combination with conventional therapies, can effectively relieve pain with fewer side effects.
AMERICAN JOURNAL OF CHINESE MEDICINE
(2023)
Article
Geriatrics & Gerontology
Michelle A. Fravel, Michael E. Ernst, Julia Gilmartin-Thomas, Robyn L. Woods, Suzanne G. Orchard, Alice J. Owen
Summary: This study found that the use of dietary supplements and complementary and alternative medicine is common among community-dwelling older adults in the United States and Australia. Factors such as female sex, US residency, higher education, polypharmacy, and frailty (in women) were significantly associated with higher use of supplements/CAMs.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2023)
Review
Pediatrics
Saskia Ribeiro Vaz, Marise Helena Tofoli, Melissa Ameloti Gomes Avelino, Paulo Sergio Sucasas da Costa
Summary: This study is a systematic review and meta-analysis of randomized controlled trials on the use of probiotics and symbiotics in treating infantile colic. The results show that probiotics can reduce the crying time of infants, with a more significant effect on exclusively breastfed infants, but the evidence of effectiveness in formula-fed and caesarean-born infants is limited.
Article
Clinical Neurology
Benedicte Marie Finger, Annika Triller, Ashley M. Bourke, Gert Jan Lammers, Christian Veauthier, Merve Yildizli, Ulf Kallweit
Summary: This study investigated the frequency and characteristics of complementary and alternative medicine (CAM) use in German narcolepsy patients. 15% of patients were using CAM at the time of the survey, and an additional 18% reported past use. The most commonly used CAM treatments were vitamins/trace elements, homeopathy, and meditation. CAM users were more likely to experience side effects from medication and have low adherence to pharmacological treatment.
Article
Integrative & Complementary Medicine
Hao-Yu Yang, Lin Han, Yi-Qun Lin, Tao Li, Yu Wei, Lin-Hua Zhao, Xiao-Lin Tong
Summary: The review discusses the progress, challenges, and opportunities in the research of probiotic fermented herbal medicine (PFHM) in traditional Chinese medicine. PFHM offers advantages such as the use of pure strains, controllable process, and production of various active enzymes during fermentation, resulting in positive pharmacological effects. However, the mechanism of PFHM needs further investigation due to the complexity of the chemical composition of traditional Chinese medicine.
AMERICAN JOURNAL OF CHINESE MEDICINE
(2023)
Article
Pediatrics
Samil Hizli, Demet Can, Ilknur Kilic, Emel Orun, Turan Tunc, Hasan Ozkan
Summary: The majority of paediatricians rely solely on clinical experience to diagnose infantile colic, and prefer using probiotic supplements and simethicone as the only medical treatment. They observed clinical benefits from these treatments, such as decreased crying duration and easier gas/stool passage.
FRONTIERS IN PEDIATRICS
(2021)
Article
Microbiology
J. A. Maldonado-Lobon, R. Blanco-Rojo, J. Maldonado, M. A. Ali, M. Almazan, A. Suanes-Cabello, E. Callejon, R. Jaldo, M. R. Benavides, A. M. Negrillo, A. Sanudo, C. Rodriguez, O. Banuelos, J. Fonolla, M. Olivares
Summary: By comparing different treatment options, it was found that Bifidobacterium breve CECT7263 had an earlier and more robust effect on infantile colic, significantly reducing daily crying time, improving night sleep, and making parents feel more positive.
BENEFICIAL MICROBES
(2021)
Article
Pediatrics
Ke Chen, Changqi Liu, Hua Li, Yuehua Lei, Chenggui Zeng, Shuhong Xu, Jianqiu Li, Francesco Savino
Summary: Probiotic treatment with B. longum CECT7894 and P. pentosaceus CECT8330 can shorten crying time, reduce crying/fussing episodes, and improve stool consistency in infants with colic, but has no significant effects on stool frequency and quality of life.
FRONTIERS IN PEDIATRICS
(2021)
Review
Pharmacology & Pharmacy
Hongmin Chu, Seunghwan Moon, Jeongsu Park, Seongjun Bak, Youme Ko, Bo-Young Youn
Summary: The development of artificial intelligence in complementary and alternative medicine has been rapidly advancing. This systematic scoping review identified three main categories of AI usage in CAM, including acupuncture treatment, tongue and lip diagnoses, and herbal medicine. Future research should focus on verifying and validating these AI models through large-scale clinical trials.
FRONTIERS IN PHARMACOLOGY
(2022)
Review
Nursing
Jennifer Simonson, Kristin Haglund, Emma Weber, Alissa Fial, Lisa Hanson
Summary: The systematic review found that oral administration of probiotics to breastfed infants with colic can reduce crying time by at least 50%, while further research is needed to study the efficacy of probiotics in reducing colic symptoms in formula-fed infants. There is currently no evidence to support or refute the efficacy of probiotics in preventing infantile colic.
MCN-THE AMERICAN JOURNAL OF MATERNAL-CHILD NURSING
(2021)
Review
Medicine, General & Internal
Jin Young Yoon, Seok-Jae Ko, Jae-Woo Park, Jae Myung Cha
Summary: Many Asian patients with functional dyspepsia (FD) are unsatisfied with conventional medical treatment and are seeking complementary and alternative medicine (CAM) therapies. However, there is limited research on CAM for FD specifically in an Asian context. Traditional herbal formulas, STW-5, peppermint and caraway, FDgard, black seed oil, and psychotherapy have been used in FD patients, but the evidence supporting their effectiveness is weak. Well-planned, large-scale studies are needed to evaluate the efficacy of CAM in treating FD, especially in Asian countries.
Article
Dermatology
Kyla N. Price, Erin K. Collier, Tristan Grogan, Jennifer M. Fernandez, Raed Alhusayen, Afsaneh Alavi, Iltefat H. Hamzavi, Michelle A. Lowes, Martina J. Porter, Jennifer L. Hsiao, Vivian Y. Shi
Summary: Recent studies have shown a widespread use of complementary and alternative medicine (CAM) among patients with HS. Providers vary in their comfort and opinions regarding CAM, with most agreeing that CAM and conventional medicine are more effective together, while citing a lack of scientific evidence as a barrier to recommending CAM.
DERMATOLOGIC THERAPY
(2021)
Review
Clinical Neurology
Panagiotis Kerezoudis, Evangelia N. Kerezoudi, Abdurehman Choudhry, Benjamin T. Himes, Ian F. Parney
Summary: Many patients and caregivers of glioma seek CAM methods to comfort themselves and cope with cancer medication side effects. This study summarizes the existing evidence on the safety and efficacy of CAM treatments for gliomas.
Article
Cardiac & Cardiovascular Systems
Raffaele Piccolo, Marisa Avvedimento, Mario Enrico Canonico, Paola Gargiulo, Roberta Paolillo, Valeria Conti, Fabrizio Dal Piaz, Amelia Filippelli, Carmine Morisco, Fiorenzo Simonetti, Attilio Leone, Alessandra Marenna, Dario Bruzzese, Giuseppe Gargiulo, Eugenio Stabile, Luigi Di Serafino, Anna Franzone, Plinio Cirillo, Giovanni Esposito
Summary: The PLINY THE ELDER trial aims to evaluate the pharmacodynamic and pharmacokinetic profile of a lower dose of ticagrelor among elderly patients during the early phase of ACS, compared with the standard dose. The results of this study will inform future clinical investigation.
CARDIOVASCULAR DRUGS AND THERAPY
(2023)
Review
Gastroenterology & Hepatology
Giovanni Di Nardo, Cesare Cremon, Annamaria Staiano, Vincenzo Stanghellini, Osvaldo Borrelli, Caterina Strisciuglio, Claudio Romano, Saverio Mallardo, Elena Scarpato, Giovanni Marasco, Silvia Salvatore, Letizia Zenzeri, Enrico Felici, Licia Pensabene, Simona Sestito, Ruggiero Francavilla, Paolo Quitadamo, Mariella Baldassarre, Valentina Giorgio, Renato Tambucci, Chiara Ziparo, Pasquale Parisi, Maria Raffaella Barbaro, Giovanni Barbara
Summary: Functional gastrointestinal disorders, such as IBS, affect many children worldwide due to disturbed neuroimmune function. Low-grade inflammation and mucosal immune activation play a significant role in symptom generation among pediatric patients with IBS, potentially influencing new therapeutic strategies.
NEUROGASTROENTEROLOGY AND MOTILITY
(2023)
Article
Nutrition & Dietetics
Caterina Strisciuglio, Sabrina Cenni, Maria Rosaria Serra, Pasquale Dolce, Sanja Kolacek, Sara Sila, Ivana Trivic, Michal Rozenfeld Bar Lev, Raanan Shamir, Aco Kostovski, Alexandra Papadopoulou, Eleftheria Roma, Christina Katsagoni, Danijela Jojkic-Pavkov, Angelo Campanozzi, Elena Scarpato, Erasmo Miele, Annamaria Staiano
Summary: 《Mediterranean diet has a protective effect on functional gastrointestinal disorders》
Article
Medicine, General & Internal
Antonino Crino, Michela Armando, Marco Crostelli, Osvaldo Mazza, Dario Bruzzese, Alessio Convertino, Danilo Fintini, Sarah Bocchini, Sara Ciccone, Alessandro Sartorio, Graziano Grugni
Summary: This study investigated the characteristics of scoliosis in individuals with Prader-Willi syndrome (PWS) and found that the prevalence of scoliosis increases with age, highlighting the importance of regular monitoring for spinal deformities in PWS patients.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cell Biology
Stefano Sanduzzi Zamparelli, Ludovica Capitelli, Nicola Coppola, Claudia Venditto, Ciro Santoro, Giuseppe Annunziata, Dario Bruzzese, Nunzia Cuomo, Ivan Gentile, Marialuisa Bocchino, Alessandro Sanduzzi Zamparelli
Summary: This study assessed the safety and feasibility of Taurisolo (R) aerosol formulation in patients with SARS-CoV-2 pneumonia, and observed a rapid decline of symptoms and a low rate of intensive care in the treatment group. This treatment could potentially serve as an add-on therapy for COVID-19 patients.
Review
Biology
Gaetana Messina, Nicola Tartaglia, Antonio Ambrosi, Chiara Porro, Angelo Campanozzi, Anna Valenzano, Gaetano Corso, Alfonso Fiorelli, Rita Polito, Mario Santini, Marcellino Monda, Domenico Tafuri, Giovanni Messina, Antonietta Messina, Vincenzo Monda
Summary: Lung cancer, as the most lethal cancer, is greatly influenced by lifestyle. Regular physical activity has a significant impact on inhibiting lung cancer progression and improving lung function and symptoms.
Article
Nutrition & Dietetics
Raffaella de Franchis, Luigi Bozza, Pasquale Canale, Maria Chiacchio, Paolo Cortese, Antonio D'Avino, Maria De Giovanni, Mirella Dello Iacovo, Antonietta D'Onofrio, Aniello Federico, Nicoletta Gasparini, Felicia Iaccarino, Giuseppe Romano, Raffaella Spadaro, Mariangela Tedesco, Giuseppe Vitiello, Angelo Antignani, Salvatore Auricchio, Vincenzo Valentino, Francesca De Filippis, Danilo Ercolini, Dario Bruzzese
Summary: Weaning infants with adult foods typical of Mediterranean Diet may promote adherence to a healthy diet and result in a more diverse and beneficial gut microbiota. A randomized controlled clinical trial showed that at 36 months, children in the Mediterranean Diet group were more likely to maintain good adherence to the diet, and their mothers were also more inclined to follow the Mediterranean Diet. At 4 years old, children in the Mediterranean Diet group had a more abundant population of beneficial bacteria.
Article
Veterinary Sciences
Dario Costanza, Adelaide Greco, Diego Piantedosi, Dario Bruzzese, Maria Pia Pasolini, Pierpaolo Coluccia, Erica Castiello, Claudia Sofia Baptista, Leonardo Meomartino
Summary: This study aimed to evaluate the agreement between heart-to-single vertebra ratio (HSVR) and vertebral heart size (VHS) and to assess the intra- and inter-observer agreement for HSVR. The results showed a strong correlation between VHS and HSVR, and HSVR demonstrated good intra- and inter-observer agreement.
VETERINARY RADIOLOGY & ULTRASOUND
(2023)
Article
Health Care Sciences & Services
Melissa Borrelli, Adele Corcione, Roberto Rongo, Elena Cantone, Iris Scala, Dario Bruzzese, Stefano Martina, Pietro Strisciuglio, Ambrosina Michelotti, Francesca Santamaria
Summary: A comprehensive evaluation of obstructive sleep apnoea (OSA) in children with Down syndrome (DS) revealed a high prevalence of sleep problems and enlarged tonsils and adenoids. Accompanied by orthodontic examination, overnight polygraphy (PG) identified OSA in a significant proportion of DS children, with moderate-severe cases showing higher levels of oxygen desaturation. The study highlights the importance of a coordinated multidisciplinary approach, including PG, in the diagnosis and management of OSA in DS.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Chemistry, Multidisciplinary
Mario Fordellone, Ilaria De Benedictis, Dario Bruzzese, Paolo Chiodini
Summary: Cancer is a leading cause of death worldwide, but early detection greatly increases treatment success. However, current detection methods relying on human experience are prone to error. This study suggests an entropy-based fuzzy clustering technique for cancer detection that outperforms conventional methods.
APPLIED SCIENCES-BASEL
(2023)
Article
Oncology
Francesco Gentile, Evelina La Civita, Bartolomeo Della Ventura, Matteo Ferro, Dario Bruzzese, Felice Crocetto, Pierre Tennstedt, Thomas Steuber, Raffaele Velotta, Daniela Terracciano
Summary: The widespread use of PSA for prostate cancer diagnosis has led to high rates of overdiagnosis and overtreatment. A combination of the Prostate Health Index (PHI) and Proclarix tests can improve risk stratification of PCa patients at initial diagnosis. An artificial neural network model combining kallikrein markers in PHI and cancer-related markers in Proclarix showed increased accuracy in identifying aggressive PCa at initial diagnosis.
Article
Pediatrics
Francesco La Torre, Maria Pia Elicio, Viviana Anna Monno, Maria Chironna, Fulvio Moramarco, Angelo Campanozzi, Adele Civino, Valerio Cecinati, Ugo Vairo, Mario Giordano, Leonardo Milella, Daniela Loconsole, Fabio Cardinale
Summary: This study aimed to understand the incidence of MIS-C in southern Italy. The cumulative incidence rate of MIS-C in children aged 0-18 years was found to be 3.27 per 100,000 residents. The study analyzed clinical features, treatment, and outcomes, and found gastrointestinal, mucocutaneous, and cardiac involvement to be the most common. Treatment was effective, as no intensive care unit admissions were required, and no cardiac sequelae were found in follow-up echocardiograms after 6 months.
Review
Pediatrics
Claudia Mandato, Angelo Colucci, Roberta Lanzillo, Annamaria Staiano, Elena Scarpato, Luigi Schiavo, Francesca Felicia Operto, Maria Rosaria Serra, Cristina Di Monaco, Julia Sara Napoli, Grazia Massa, Pietro Vajro
Summary: Purpose of this study was to explore the role of lifestyle and diet in the development and progression of multiple sclerosis (MS) and investigate the potential benefits of diets and dietary supplementations in improving patient outcomes. Findings revealed that there is no universally best diet for MS, but healthy and balanced diets rich in fruits, vegetables, whole grains, and lean proteins while limiting processed foods, sugar, and saturated fat appear to have antioxidant and anti-inflammatory properties and promote a gut microbiota that supports gut and brain barriers. Vitamin D and polyunsaturated fatty acids are the most studied supplements for reducing MS-associated inflammation. In addition, counseling on appropriate diet and maintaining physical activity is recommended for MS prevention and management in both adults and children until more research is available on newer approaches.
Article
Gastroenterology & Hepatology
Massimo Martinelli, Erminia Romeo, Tamara Caldaro, Konstantina Dimakou, Alexandra Papadopoulou, Manar Matar, Amit Assa, Valeria Dipasquale, Claudio Romano, Marina Aloi, Patrizia Alvisi, Dennis Roser, Kaija Leena Kolho, Nadeem Afzal, Oren Ledder, Schlomi Cohen, Jiri Bronsky, Johanna C. Escher, Annecarin Brueckner, Raanan Shamir, Annamaria Staiano, Erasmo Miele
Summary: This study aimed to determine the prevalence and predictive factors of Crohn's disease (CD) in children with ulcerative colitis (UC) after ileal pouch-anal anastomosis (IPAA). The results showed that children with UC undergoing IPAA had a high risk of developing subsequent CD, and a decreased preoperative body mass index was identified as a possible predictive factor for new-onset CD.
INFLAMMATORY BOWEL DISEASES
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
Marialuisa Bocchino, Gaetano Rea, Ludovica Capitelli, Roberta Lieto, Dario Bruzzese
Summary: A systematic review and meta-analysis of 1-year follow-up chest CT scans in post-COVID-19 patients revealed highly heterogeneous prevalence of lung sequelae, with unknown determinants of heterogeneity. Caution should be exercised in interpreting the data.
