dl-3-n-Butylphthalide (NBP) Provides Neuroprotection in the Mice Models After Traumatic Brain Injury via Nrf2-ARE Signaling Pathway

Dl-3-n-butylphthalide-induced upregulation of antioxidant defense is involved in the enhancement of cross talk between CREB and Nrf2 in an Alzheimer's disease mouse model

(2016) Chun-Yan Wang et al.   NEUROBIOLOGY OF AGING

DL-3-n-butylphthalide delays the onset and progression of diabetic cataract by inhibiting oxidative stress in rat diabetic model

(2016) Fuxu Wang et al.   Scientific Reports

The Role of Serial Oxidative Stress Levels in Acute Traumatic Brain Injury and as Predictors of Outcome

(2016) Hung-Chen Wang et al.   World Neurosurgery

The Keap1-Nrf2-antioxidant response element pathway: A review of its regulation by melatonin and the proteasome

(2015) Jerry Vriend et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Alpha lipoic acid inhibits neural apoptosis via a mitochondrial pathway in rats following traumatic brain injury

(2015) Wuting Wei et al.   NEUROCHEMISTRY INTERNATIONAL

Melatonin protects the brain from apoptosis by enhancement of autophagy after traumatic brain injury in mice

(2015) Ke Ding et al.   NEUROCHEMISTRY INTERNATIONAL

Luteolin provides neuroprotection in models of traumatic brain injury via the Nrf2–ARE pathway

(2014) Jianguo Xu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Melatonin stimulates antioxidant enzymes and reduces oxidative stress in experimental traumatic brain injury: the Nrf2–ARE signaling pathway as a potential mechanism

(2014) Ke Ding et al.   FREE RADICAL BIOLOGY AND MEDICINE

Anti-inflammatory effects of curcumin in experimental spinal cord injury in rats

(2014) Wei Jin et al.   INFLAMMATION RESEARCH

Modulating autophagy affects neuroamyloidogenesis in an in vitro ischemic stroke model

(2014) T. Zhang et al.   NEUROSCIENCE

L-3-n-butylphthalide protects rats' cardiomyocytes from ischaemia/reperfusion-induced apoptosis by affecting the mitochondrial apoptosis pathway

(2013) Y.-G. Wang et al.   Acta Physiologica

Traumatic Brain Injury: Oxidative Stress and Neuroprotection

(2013) Carolin Cornelius et al.   ANTIOXIDANTS & REDOX SIGNALING

Nrf2/ARE pathway activation, HO-1 and NQO1 induction by polychlorinated biphenyl quinone is associated with reactive oxygen species and PI3K/AKT signaling

(2013) Lingrui Li et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Dihydroquercetin (DHQ) Induced HO-1 and NQO1 Expression against Oxidative Stress through the Nrf2-Dependent Antioxidant Pathway

(2013) Lu Liang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Hydrogen-rich saline alleviates early brain injury via reducing oxidative stress and brain edema following experimental subarachnoid hemorrhage in rabbits

(2012) Zong Zhuang et al.   BMC NEUROSCIENCE

DL-3-n-Butylphthalide, an Anti-Oxidant Agent, Prevents Neurological Deficits and Cerebral Injury Following Stroke per Functional Analysis, Magnetic Resonance Imaging and Histological Assessment

(2012) Lihong Zhang et al.   CURRENT NEUROVASCULAR RESEARCH

dl-3-n-Butylphthalide protects rat bone marrow stem cells against hydrogen peroxide-induced cell death through antioxidation and activation of PI3K-Akt pathway

(2012) Bo Sun et al.   NEUROSCIENCE LETTERS

Emerging roles of Nrf2 and phase II antioxidant enzymes in neuroprotection

(2012) Meijuan Zhang et al.   PROGRESS IN NEUROBIOLOGY

Protective effect of tert-butylhydroquinone on cerebral inflammatory response following traumatic brain injury in mice

(2011) Wei Jin et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

Dl-3-n-butylphthalide, a natural antioxidant, protects dopamine neurons in rotenone models for Parkinson's disease

(2011) Nian Xiong et al.   NEUROBIOLOGY OF AGING

dl-3-n-butylphthalide extends survival by attenuating glial activation in a mouse model of amyotrophic lateral sclerosis

(2011) Xinhong Feng et al.   NEUROPHARMACOLOGY

The role of Nrf2 signaling in the regulation of antioxidants and detoxifying enzymes after traumatic brain injury in rats and mice

(2010) Yuan Hong et al.   ACTA PHARMACOLOGICA SINICA

dl-3-n-Butylphthalide prevents neuronal cell death after focal cerebral ischemia in mice via the JNK pathway

(2010) Jimei Li et al.   BRAIN RESEARCH

L-3-n-Butylphthalide Improves Cognitive Impairment and Reduces Amyloid-  in a Transgenic Model of Alzheimer's Disease

(2010) Y. Peng et al.   JOURNAL OF NEUROSCIENCE

3-n-butylphthalide (NBP) reduces apoptosis and enhances vascular endothelial growth factor (VEGF) up-regulation in diabetic rats

(2010) Ting Zhang et al.   NEUROLOGICAL RESEARCH

dl-3-n-Butylphthalide prevents oxidative damage and reduces mitochondrial dysfunction in an MPP+-induced cellular model of Parkinson's disease

(2010) Jin-zhong Huang et al.   NEUROSCIENCE LETTERS

dl-3-n-butylphthalide protects endothelial cells against oxidative/nitrosative stress, mitochondrial damage and subsequent cell death after oxygen glucose deprivation in vitro

(2009) Ling Li et al.   BRAIN RESEARCH

Mouse closed head injury model induced by a weight-drop device

(2009) Michael A Flierl et al.   Nature Protocols

Increased intestinal inflammatory response and gut barrier dysfunction in Nrf2-deficient mice after traumatic brain injury

(2008) Wei Jin et al.   CYTOKINE

Activation of Nrf2–ARE pathway in brain after traumatic brain injury

(2008) Wei Yan et al.   NEUROSCIENCE LETTERS