Diffuse high-grade gliomas with H3 K27M mutations carry a dismal prognosis independent of tumor location

Evidence of H3 K27M mutations in posterior fossa ependymomas

(2016) Marco Gessi et al.   ACTA NEUROPATHOLOGICA

Targeted detection of genetic alterations reveal the prognostic impact of H3K27M and MAPK pathway aberrations in paediatric thalamic glioma

(2016) Scott Ryall et al.   Acta Neuropathologica Communications

Integrated analysis of pediatric glioblastoma reveals a subset of biologically favorable tumors with associated molecular prognostic markers

(2015) Andrey Korshunov et al.   ACTA NEUROPATHOLOGICA

Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes

(2015) David Castel et al.   ACTA NEUROPATHOLOGICA

High frequency of H3F3A K27M mutations characterizes pediatric and adult high-grade gliomas of the spinal cord

(2015) Marco Gessi et al.   ACTA NEUROPATHOLOGICA

Diffuse Midline Gliomas with Histone H3-K27M Mutation: A Series of 47 Cases Assessing the Spectrum of Morphologic Variation and Associated Genetic Alterations

(2015) David A. Solomon et al.   BRAIN PATHOLOGY

The H3.3 K27M mutation results in a poorer prognosis in brainstem gliomas than thalamic gliomas in adults

(2015) Jie Feng et al.   HUMAN PATHOLOGY

BRAFMutation andCDKN2ADeletion Define a Clinically Distinct Subgroup of Childhood Secondary High-Grade Glioma

(2015) Matthew Mistry et al.   JOURNAL OF CLINICAL ONCOLOGY

Evidence forBRAFV600E andH3F3AK27M double mutations in paediatric glial and glioneuronal tumours

(2015) Anh Tuan Nguyen et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Histopathological spectrum of paediatric diffuse intrinsic pontine glioma: diagnostic and therapeutic implications

(2014) Pawel Buczkowicz et al.   ACTA NEUROPATHOLOGICA

Genetic Analysis of Diffuse High-Grade Astrocytomas in Infancy Defines a Novel Molecular Entity

(2014) Gerrit H. Gielen et al.   BRAIN PATHOLOGY

RevisitingTP53Mutations and Immunohistochemistry-A Comparative Study in 157 Diffuse Gliomas

(2014) Hirokazu Takami et al.   BRAIN PATHOLOGY

H3F3A K27M Mutation in Pediatric CNS Tumors

(2013) Gerrit H. Gielen et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Chromatin Remodeling Defects in Pediatric and Young Adult Glioblastoma: A Tale of a Variant Histone 3 Tail

(2013) Adam M. Fontebasso et al.   BRAIN PATHOLOGY

Cerebellar location may predict an unfavourable prognosis in paediatric high-grade glioma

(2013) M Karremann et al.   BRITISH JOURNAL OF CANCER

Reduced H3K27me3 and DNA Hypomethylation Are Major Drivers of Gene Expression in K27M Mutant Pediatric High-Grade Gliomas

(2013) Sebastian Bender et al.   CANCER CELL

The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression

(2013) K.-M. Chan et al.   GENES & DEVELOPMENT

Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

(2013) David T W Jones et al.   NATURE GENETICS

Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas

(2013)   NATURE GENETICS

H3F3A K27M mutations in thalamic gliomas from young adult patients

(2013) Koki Aihara et al.   NEURO-ONCOLOGY

Inhibition of PRC2 Activity by a Gain-of-Function H3 Mutation Found in Pediatric Glioblastoma

(2013) P. W. Lewis et al.   SCIENCE

K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas

(2012) Dong-Anh Khuong-Quang et al.   ACTA NEUROPATHOLOGICA

Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma

(2012) Dominik Sturm et al.   CANCER CELL

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

(2012) Jeremy Schwartzentruber et al.   NATURE

Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas

(2012) Gang Wu et al.   NATURE GENETICS

Thalamic high-grade gliomas in children: a distinct clinical subset?

(2011) C. M. Kramm et al.   NEURO-ONCOLOGY

High dose methotrexate for pediatric high grade glioma: results of the HIT-GBM-D Pilot study

(2010) Johannes E. Wolff et al.   JOURNAL OF NEURO-ONCOLOGY

Intensive chemotherapy improves survival in pediatric high-grade glioma after gross total resection: results of the HIT-GBM-C protocol

(2009) Johannes E.A. Wolff et al.   CANCER

Young age may predict a better outcome for children with diffuse pontine glioma

(2008) Alberto Broniscer et al.   CANCER