Reducing the RNA binding protein TIA1 protects against tau-mediated neurodegeneration in vivo

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Biomolecular condensates: organizers of cellular biochemistry

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Dysregulation of RNA Binding Protein Aggregation in Neurodegenerative Disorders

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Compositional Control of Phase-Separated Cellular Bodies

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Coexisting Liquid Phases Underlie Nucleolar Subcompartments

(2016) Marina Feric et al.   CELL

Mechanistic insights into mammalian stress granule dynamics

(2016) Marc D. Panas et al.   JOURNAL OF CELL BIOLOGY

Pathological Tau Promotes Neuronal Damage by Impairing Ribosomal Function and Decreasing Protein Synthesis

(2016) S. Meier et al.   JOURNAL OF NEUROSCIENCE

Decoding ALS: from genes to mechanism

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Pathological conformations involving the amino terminus of tau occur early in Alzheimer's disease and are differentially detected by monoclonal antibodies

(2016) Benjamin Combs et al.   NEUROBIOLOGY OF DISEASE

Interaction of tau with the RNA-Binding Protein TIA1 Regulates tau Pathophysiology and Toxicity

(2016) Tara Vanderweyde et al.   Cell Reports

Internalized Tau sensitizes cells to stress by promoting formation and stability of stress granules

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Assessing rodent hippocampal involvement in the novel object recognition task. A review

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Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization

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A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation

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Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins

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Phase Transition of a Disordered Nuage Protein Generates Environmentally Responsive Membraneless Organelles

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Frontotemporal lobar degeneration: defining phenotypic diversity through personalized medicine

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Distinct Tau Prion Strains Propagate in Cells and Mice and Define Different Tauopathies

(2014) David W. Sanders et al.   NEURON

Lost after translation: missorting of Tau protein and consequences for Alzheimer disease

(2014) Hans Zempel et al.   TRENDS IN NEUROSCIENCES

RNA Protein Interaction in Neurons

(2013) Robert B. Darnell   Annual Review of Neuroscience

Stress granules as crucibles of ALS pathogenesis

(2013) Yun R. Li et al.   JOURNAL OF CELL BIOLOGY

Object recognition test in mice

(2013) Marianne Leger et al.   Nature Protocols

Converging Mechanisms in ALS and FTD: Disrupted RNA and Protein Homeostasis

(2013) Shuo-Chien Ling et al.   NEURON

Neurofibrillary tangle-bearing neurons are functionally integrated in cortical circuits in vivo

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Contrasting Pathology of the Stress Granule Proteins TIA-1 and G3BP in Tauopathies

(2012) T. Vanderweyde et al.   JOURNAL OF NEUROSCIENCE

Regulated protein aggregation: stress granules and neurodegeneration

(2012) Benjamin Wolozin   Molecular Neurodegeneration

Phase transitions in the assembly of multivalent signalling proteins

(2012) Pilong Li et al.   NATURE

RNA-binding proteins with prion-like domains in ALS and FTLD-U

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Caspase activation precedes and leads to tangles

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Structural and functional changes in tau mutant mice neurons are not linked to the presence of NFTs

(2009) A.B. Rocher et al.   EXPERIMENTAL NEUROLOGY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Stress granules: the Tao of RNA triage

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