Hydrogels with precisely controlled integrin activation dictate vascular patterning and permeability

Design principles for therapeutic angiogenic materials

(2016) Priscilla S. Briquez et al.   Nature Reviews Materials

Enzyme-Responsive Delivery of Multiple Proteins with Spatiotemporal Control

(2015) Suwei Zhu et al.   ADVANCED MATERIALS

Integrin α3β1 Binding to Fibronectin Is Dependent on the Ninth Type III Repeat

(2015) Ashley C. Brown et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integrin β1 controls VE-cadherin localization and blood vessel stability

(2015) Hiroyuki Yamamoto et al.   Nature Communications

Bone regeneration using an alpha 2 beta 1 integrin-specific hydrogel as a BMP-2 delivery vehicle

(2014) Asha Shekaran et al.   BIOMATERIALS

Chemical sintering generates uniform porous hyaluronic acid hydrogels

(2013) Cynthia Cam et al.   Acta Biomaterialia

The modulation of MSC integrin expression by RGD presentation

(2013) Jonathan Lam et al.   BIOMATERIALS

In Vivo Analysis Reveals a Highly Stereotypic Morphogenetic Pathway of Vascular Anastomosis

(2013) Anna Lenard et al.   DEVELOPMENTAL CELL

Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs

(2013) Neil C Henderson et al.   NATURE MEDICINE

GFOGER-Modified MMP-Sensitive Polyethylene Glycol Hydrogels Induce Chondrogenic Differentiation of Human Mesenchymal Stem Cells

(2013) Rami Mhanna et al.   TISSUE ENGINEERING PART A

VEGF gene therapy: therapeutic angiogenesis in the clinic and beyond

(2012) M Giacca et al.   GENE THERAPY

Directing epithelial to mesenchymal transition through engineered microenvironments displaying orthogonal adhesive and mechanical cues

(2012) Marilyn C. Markowski et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Engineering the Growth Factor Microenvironment with Fibronectin Domains to Promote Wound and Bone Tissue Healing

(2011) M. M. Martino et al.   Science Translational Medicine

The CCR2/CCL2 Interaction Mediates the Transendothelial Recruitment of Intravascularly Delivered Neural Stem Cells to the Ischemic Brain

(2011) Robert H. Andres et al.   STROKE

The spreading, migration and proliferation of mouse mesenchymal stem cells cultured inside hyaluronic acid hydrogels

(2010) Yuguo Lei et al.   BIOMATERIALS

β1 Integrin Establishes Endothelial Cell Polarity and Arteriolar Lumen Formation via a Par3-Dependent Mechanism

(2010) Ann C. Zovein et al.   DEVELOPMENTAL CELL

Anchorage of VEGF to the extracellular matrix conveys differential signaling responses to endothelial cells

(2010) Tom T. Chen et al.   JOURNAL OF CELL BIOLOGY

Guiding Epithelial Cell Phenotypes with Engineered Integrin-Specific Recombinant Fibronectin Fragments

(2010) Ashley C. Brown et al.   TISSUE ENGINEERING PART A

Engineering integrin signaling for promoting embryonic stem cell self-renewal in a precisely defined niche

(2009) Seung Tae Lee et al.   BIOMATERIALS

Brain angiogenesis in developmental and pathological processes: neurovascular injury and angiogenic recovery after stroke

(2009) Ken Arai et al.   FEBS Journal

The Integrin Antagonist Cilengitide Activates αVβ3, Disrupts VE-Cadherin Localization at Cell Junctions and Enhances Permeability in Endothelial Cells

(2009) Gian Carlo Alghisi et al.   PLoS One

Stable Vascular Connections and Remodeling Require Full Expression of VE-Cadherin in Zebrafish Embryos

(2009) Mercedes Montero-Balaguer et al.   PLoS One

The Extracellular Matrix: Not Just Pretty Fibrils

(2009) R. O. Hynes   SCIENCE

Controlling integrin specificity and stem cell differentiation in 2D and 3D environments through regulation of fibronectin domain stability

(2008) Mikaël M. Martino et al.   BIOMATERIALS

DNA delivery from matrix metalloproteinase degradable poly(ethylene glycol) hydrogels to mouse cloned mesenchymal stem cells

(2008) Yuguo Lei et al.   BIOMATERIALS

Integrin β1 Subunit Controls Mural Cell Adhesion, Spreading, and Blood Vessel Wall Stability

(2008) Sabu Abraham et al.   CIRCULATION RESEARCH

Integrin αvβ3-targeted cancer therapy

(2008) Zhaofei Liu et al.   DRUG DEVELOPMENT RESEARCH