Dense genotyping of immune-related loci implicates host responses to microbial exposure in Behçet's disease susceptibility

C13orf31 (FAMIN) is a central regulator of immunometabolic function

(2016) M Zaeem Cader et al.   NATURE IMMUNOLOGY

Genetic Analysis with the Immunochip Platform in Behçet Disease. Identification of Residues Associated in the HLA Class I Region and New Susceptibility Loci

(2016) Lourdes Ortiz-Fernández et al.   PLoS One

The landscape of genomic imprinting across diverse adult human tissues

(2015) Yael Baran et al.   GENOME RESEARCH

Increased expression of the NLRP3 inflammasome components in patients with Behçet’s disease

(2015) En Hyung Kim et al.   Journal of Inflammation-London

Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy

(2015) Hong Liu et al.   NATURE GENETICS

Genome-Wide Association Study in an Admixed Case Series Reveals IL12A as a New Candidate in Behçet Disease

(2015) Jasper H. Kappen et al.   PLoS One

Fut2genotype is a risk factor for dominant stenosis and biliary candida infections in primary sclerosing cholangitis

(2014) C. Rupp et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Study of Mendelian forms of Crohn's disease in Saudi Arabia reveals novel risk loci and alleles

(2014) Nisha Patel et al.   GUT

NOD2 and CCDC122-LACC1 genes are associated with leprosy susceptibility in Brazilians

(2014) Carolinne Sales-Marques et al.   HUMAN GENETICS

Associations ofFUT2andFUT3gene polymorphisms with Crohn's disease in Chinese patients

(2014) Ding-yuan Hu et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Biological Treatments in Behçet’s Disease: Beyond Anti-TNF Therapy

(2014) Francesco Caso et al.   MEDIATORS OF INFLAMMATION

Behcet disease-associated MHC class I residues implicate antigen binding and regulation of cell-mediated cytotoxicity

(2014) M. J. Ombrello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Association of a Mutation inLACC1With a Monogenic Form of Systemic Juvenile Idiopathic Arthritis

(2014) Salma M. Wakil et al.   Arthritis & Rheumatology

FUT2: filling the gap between genes and environment in Behçet's disease?

(2013) Joana M Xavier et al.   ANNALS OF THE RHEUMATIC DISEASES

Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1

(2013) Yohei Kirino et al.   NATURE GENETICS

Identification of multiple independent susceptibility loci in the HLA region in Behçet's disease

(2013) Travis Hughes et al.   NATURE GENETICS

Systematic identification of trans eQTLs as putative drivers of known disease associations

(2013) Harm-Jan Westra et al.   NATURE GENETICS

Imputing Amino Acid Polymorphisms in Human Leukocyte Antigens

(2013) Xiaoming Jia et al.   PLoS One

Targeted resequencing implicates the familial Mediterranean fever gene MEFV and the toll-like receptor 4 gene TLR4 in Behcet disease

(2013) Y. Kirino et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TNFAIP3 gene polymorphisms confer risk for Behcet’s disease in a Chinese Han population

(2012) Hong Li et al.   HUMAN GENETICS

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

Mapping cis- and trans-regulatory effects across multiple tissues in twins

(2012) Elin Grundberg et al.   NATURE GENETICS

Interleukin-1β-regulating antibody XOMA 052 (gevokizumab) in the treatment of acute exacerbations of resistant uveitis of Behçet's disease: an open-label pilot study

(2011) Ahmet Gül et al.   ANNALS OF THE RHEUMATIC DISEASES

A linear complexity phasing method for thousands of genomes

(2011) Olivier Delaneau et al.   NATURE METHODS

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

(2011) L. D. Ward et al.   NUCLEIC ACIDS RESEARCH

HLA-B*51 and Behçet Disease

(2011) Ahmet Gul et al.   OCULAR IMMUNOLOGY AND INFLAMMATION

Secretor Genotype (FUT2 gene) Is Strongly Associated with the Composition of Bifidobacteria in the Human Intestine

(2011) Pirjo Wacklin et al.   PLoS One

Colonic mucosa-associated microbiota is influenced by an interaction of Crohn disease and FUT2 (Secretor) genotype

(2011) P. Rausch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Promise and pitfalls of the Immunochip

(2011) Adrian Cortes et al.   ARTHRITIS RESEARCH & THERAPY

Genevar: a database and Java application for the analysis and visualization of SNP-gene associations in eQTL studies

(2010) T.-P. Yang et al.   BIOINFORMATICS

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

Genome-wide association studies identify IL23R-IL12RB2 and IL10 as Behçet's disease susceptibility loci

(2010) Nobuhisa Mizuki et al.   NATURE GENETICS

Genome-wide association study identifies variants in the MHC class I, IL10 and IL23R-IL12RB2 regions associated with Behçet's disease

(2010) Elaine F Remmers et al.   NATURE GENETICS

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

HLA-B51/B5and the risk of Behçet's disease: A systematic review and meta-analysis of case-control genetic association studies

(2009) Mathilde de Menthon et al.   ARTHRITIS AND RHEUMATISM

A Natural History of FUT2 Polymorphism in Humans

(2009) A. Ferrer-Admetlla et al.   MOLECULAR BIOLOGY AND EVOLUTION

Genomewide Association Study of Leprosy

(2009) Fu-Ren Zhang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Long-Range LD Can Confound Genome Scans in Admixed Populations

(2008) Alkes L. Price et al.   AMERICAN JOURNAL OF HUMAN GENETICS

EULAR recommendations for the management of Behcet disease

(2008) G Hatemi et al.   ANNALS OF THE RHEUMATIC DISEASES