Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor

Recessive nephrocerebellar syndrome on the Galloway-Mowat syndrome spectrum is caused by homozygous protein-truncating mutations ofWDR73

(2015) Robert N. Jinks et al.   BRAIN

Cancer Risk in Relatives of Testicular Cancer Patients by Histology Type and Age at Diagnosis: A Joint Study from Five Nordic Countries

(2015) Elham Kharazmi et al.   EUROPEAN UROLOGY

Two new loci and gene sets related to sex determination and cancer progression are associated with susceptibility to testicular germ cell tumor

(2015) W. Kristiansen et al.   HUMAN MOLECULAR GENETICS

Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C

(2015) Borbala Mifsud et al.   NATURE GENETICS

Microtubule detyrosination guides chromosomes during mitosis

(2015) M. Barisic et al.   SCIENCE

Identification of four new susceptibility loci for testicular germ cell tumour

(2015) Kevin Litchfield et al.   Nature Communications

Whole-exome sequencing reveals the mutational spectrum of testicular germ cell tumours

(2015) Kevin Litchfield et al.   Nature Communications

Common variants identified in genome-wide association studies of testicular germ cell tumour: an update, biological insights and clinical application

(2015) K. Litchfield et al.   Andrology

Changes in the expression profiles of claudins during gonocyte differentiation and in seminomas

(2015) G. Manku et al.   Andrology

The Ensembl Regulatory Build

(2015) Daniel R Zerbino et al.   GENOME BIOLOGY

Quantifying the heritability of testicular germ cell tumour using both population-based and genomic approaches

(2015) Kevin Litchfield et al.   Scientific Reports

Loss-of-Function Mutations in WDR73 Are Responsible for Microcephaly and Steroid-Resistant Nephrotic Syndrome: Galloway-Mowat Syndrome

(2014) Estelle Colin et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping

(2014) Suhas S.P. Rao et al.   CELL

Multi-stage genome-wide association study identifies new susceptibility locus for testicular germ cell tumour on chromosome 3q25

(2014) K. Litchfield et al.   HUMAN MOLECULAR GENETICS

Depletion of pericentrin in mouse oocytes disrupts microtubule organizing center function and meiotic spindle organization

(2014) Wei Ma et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

visPIG - A Web Tool for Producing Multi-Region, Multi-Track, Multi-Scale Plots of Genetic Data

(2014) Matthew Scales et al.   PLoS One

A Polymorphic p53 Response Element in KIT Ligand Influences Cancer Risk and Has Undergone Natural Selection

(2013) Jorge Zeron-Medina et al.   CELL

Testicular cancer incidence to rise by 25% by 2025 in Europe? Model-based predictions in 40 countries using population-based registry data

(2013) Charlotte Le Cornet et al.   EUROPEAN JOURNAL OF CANCER

Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14

(2013) Elise Ruark et al.   NATURE GENETICS

Meta-analysis identifies four new loci associated with testicular germ cell tumor

(2013) Charles C Chung et al.   NATURE GENETICS

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

(2013) Stig E Bojesen et al.   NATURE GENETICS

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

Systematic discovery and characterization of regulatory motifs in ENCODE TF binding experiments

(2013) P. Kheradpour et al.   NUCLEIC ACIDS RESEARCH

Tex14, a Plk1-Regulated Protein, Is Required for Kinetochore-Microtubule Attachment and Regulation of the Spindle Assembly Checkpoint

(2012) Gourish Mondal et al.   MOLECULAR CELL

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Breast cancer risk–associated SNPs modulate the affinity of chromatin for FOXA1 and alter gene expression

(2012) Richard Cowper-Sal·lari et al.   NATURE GENETICS

Fast and accurate genotype imputation in genome-wide association studies through pre-phasing

(2012) Bryan Howie et al.   NATURE GENETICS

ChromHMM: automating chromatin-state discovery and characterization

(2012) Jason Ernst et al.   NATURE METHODS

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Primer3—new capabilities and interfaces

(2012) Andreas Untergasser et al.   NUCLEIC ACIDS RESEARCH

Specification of the germ cell lineage in mice: A process orchestrated by the PR-domain proteins, Blimp1 and Prdm14

(2011) Kazuki Kurimoto et al.   CELL CYCLE

A second independent locus within DMRT1 is associated with testicular germ cell tumor susceptibility

(2011) Peter A. Kanetsky et al.   HUMAN MOLECULAR GENETICS

Genome-wide association studies provide new insights into the genetic basis of testicular germ-cell tumour

(2011) C. Turnbull et al.   INTERNATIONAL JOURNAL OF ANDROLOGY

A GATA4-regulated tumor suppressor network represses formation of malignant human astrocytomas

(2011) Sameer Agnihotri et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A linear complexity phasing method for thousands of genomes

(2011) Olivier Delaneau et al.   NATURE METHODS

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

(2011) L. D. Ward et al.   NUCLEIC ACIDS RESEARCH

The MIS12 complex is a protein interaction hub for outer kinetochore assembly

(2010) Arsen Petrovic et al.   JOURNAL OF CELL BIOLOGY

Differential Roles of Sall4 Isoforms in Embryonic Stem Cell Pluripotency

(2010) S. Rao et al.   MOLECULAR AND CELLULAR BIOLOGY

Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer

(2010) Clare Turnbull et al.   NATURE GENETICS

Meta-analysis and imputation refines the association of 15q25 with smoking quantity

(2010) Jason Z Liu et al.   NATURE GENETICS

Genotype imputation for genome-wide association studies

(2010) Jonathan Marchini et al.   NATURE REVIEWS GENETICS

Enhanced genomic instabilities caused by deregulated microtubule dynamics and chromosome segregation: a perspective from genetic studies in mice

(2009) C. V. Rao et al.   CARCINOGENESIS

A Signaling Principle for the Specification of the Germ Cell Lineage in Mice

(2009) Yasuhide Ohinata et al.   CELL

GATA4 and GATA5 are Potential Tumor Suppressors and Biomarkers in Colorectal Cancer

(2009) D. M.E.I. Hellebrekers et al.   CLINICAL CANCER RESEARCH

Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer

(2009) Peter A Kanetsky et al.   NATURE GENETICS

A genome-wide association study of testicular germ cell tumor

(2009) Elizabeth A Rapley et al.   NATURE GENETICS

Identification of low penetrance alleles for lung cancer: The GEnetic Lung CAncer Predisposition Study (GELCAPS)

(2008) Tim Eisen et al.   BMC CANCER

Critical function of Prdm14 for the establishment of the germ cell lineage in mice

(2008) Masashi Yamaji et al.   NATURE GENETICS