Frequency of mononuclear diploid cardiomyocytes underlies natural variation in heart regeneration

Analysis of protein-coding genetic variation in 60,706 humans

(2016) Monkol Lek et al.   NATURE

Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR study

(2016) Frederick E. Dewey et al.   SCIENCE

Cardiomyocytes in Young Infants With Congenital Heart Disease: a Three-Month Window of Proliferation

(2016) Lincai Ye et al.   Scientific Reports

Whole exome sequencing identifies the TNNI3K gene as a cause of familial conduction system disease and congenital junctional ectopic tachycardia

(2015) Yanwei Xi et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation

(2015) Gabriele D’Uva et al.   NATURE CELL BIOLOGY

When bigger is better: the role of polyploidy in organogenesis

(2015) Terry L. Orr-Weaver   TRENDS IN GENETICS

High-Density Genotypes of Inbred Mouse Strains: Improved Power and Precision of Association Mapping

(2015) Christoph D. Rau et al.   G3-Genes Genomes Genetics

Genetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred Strains

(2015) Brian J. Bennett et al.   PLoS Genetics

The Oxygen-Rich Postnatal Environment Induces Cardiomyocyte Cell-Cycle Arrest through DNA Damage Response

(2014) Bao N. Puente et al.   CELL

TNNI3K mutation in familial syndrome of conduction system disease, atrial tachyarrhythmia and dilated cardiomyopathy

(2014) Jeanne L. Theis et al.   HUMAN MOLECULAR GENETICS

c-kit+ cells minimally contribute cardiomyocytes to the heart

(2014) Jop H. van Berlo et al.   NATURE

Existing cardiomyocytes generate cardiomyocytes at a low rate after birth in mice

(2014) S. R. Ali et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Long-Range Chromatin Contacts in Embryonic Stem Cells Reveal a Role for Pluripotency Factors and Polycomb Proteins in Genome Organization

(2013) Matthew Denholtz et al.   Cell Stem Cell

Meis1 regulates postnatal cardiomyocyte cell cycle arrest

(2013) Ahmed I. Mahmoud et al.   NATURE

Isolation and in vitro culture of primary cardiomyocytes from adult zebrafish hearts

(2013) Veronika Sander et al.   Nature Protocols

Contribution of Bone Marrow-Derived Hematopoietic Stem/Progenitor Cells to the Generation of Donor-Marker+ Cardiomyocytes In Vivo

(2013) Mitsuhiro Fukata et al.   PLoS One

Igf Signaling is Required for Cardiomyocyte Proliferation during Zebrafish Heart Development and Regeneration

(2013) Ying Huang et al.   PLoS One

High Fat Feeding in Mice Is Insufficient to Induce Cardiac Dysfunction and Does Not Exacerbate Heart Failure

(2013) Robert E. Brainard et al.   PLoS One

Cardiomyocyte proliferation contributes to heart growth in young humans

(2013) Mariya Mollova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of the Cardiomyocyte-Specific Kinase TNNI3K Limits Oxidative Stress, Injury, and Adverse Remodeling in the Ischemic Heart

(2013) R. J. Vagnozzi et al.   Science Translational Medicine

Cardiac Regenerative Capacity and Mechanisms

(2012) Kazu Kikuchi et al.   Annual Review of Cell and Developmental Biology

Comparison of co-expression measures: mutual information, correlation, and model based indices

(2012) Lin Song et al.   BMC BIOINFORMATICS

Cardiomyocyte proliferation and progenitor cell recruitment underlie therapeutic regeneration after myocardial infarction in the adult mouse heart

(2012) Konstantinos Malliaras et al.   EMBO Molecular Medicine

Overexpression of TNNI3K, a cardiac-specific MAPKKK, promotes cardiac dysfunction

(2012) Hao Tang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits

(2012) Anatole Ghazalpour et al.   MAMMALIAN GENOME

Mammalian heart renewal by pre-existing cardiomyocytes

(2012) Samuel E. Senyo et al.   NATURE

Dissection of a Quantitative Trait Locus for PR Interval Duration Identifies Tnni3k as a Novel Modulator of Cardiac Conduction

(2012) Elisabeth M. Lodder et al.   PLoS Genetics

Heart regeneration

(2011) Michael A. Laflamme et al.   NATURE

Transient Regenerative Potential of the Neonatal Mouse Heart

(2011) E. R. Porrello et al.   SCIENCE

A Novel and Efficient Model of Coronary Artery Ligation and Myocardial Infarction in the Mouse

(2010) Erhe Gao et al.   CIRCULATION RESEARCH

Identification of cardiomyocyte nuclei and assessment of ploidy for the analysis of cell turnover

(2010) Olaf Bergmann et al.   EXPERIMENTAL CELL RESEARCH

A high-resolution association mapping panel for the dissection of complex traits in mice

(2010) B. J. Bennett et al.   GENOME RESEARCH

Primary contribution to zebrafish heart regeneration by gata4 + cardiomyocytes

(2010) Kazu Kikuchi et al.   NATURE

Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation

(2010) Chris Jopling et al.   NATURE

Neuregulin1/ErbB4 Signaling Induces Cardiomyocyte Proliferation and Repair of Heart Injury

(2009) Kevin Bersell et al.   CELL

Evidence for Cardiomyocyte Renewal in Humans

(2009) Olaf Bergmann et al.   SCIENCE

Tnni3k Modifies Disease Progression in Murine Models of Cardiomyopathy

(2009) Ferrin C. Wheeler et al.   PLoS Genetics