Control of intestinal stem cell function and proliferation by mitochondrial pyruvate metabolism
出版年份 2017 全文链接
标题
Control of intestinal stem cell function and proliferation by mitochondrial pyruvate metabolism
作者
关键词
-
出版物
NATURE CELL BIOLOGY
Volume 19, Issue 9, Pages 1027-1036
出版商
Springer Nature
发表日期
2017-08-14
DOI
10.1038/ncb3593
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Interplay between metabolic identities in the intestinal crypt supports stem cell function
- (2017) Maria J. Rodríguez-Colman et al. NATURE
- Drosophilalarvae synthesize the putative oncometabolite L-2-hydroxyglutarate during normal developmental growth
- (2017) Hongde Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Gastrointestinal stem cells in health and disease: from flies to humans
- (2016) Hongjie Li et al. Disease Models & Mechanisms
- Epigenetics in Intestinal Epithelial Cell Renewal
- (2016) Alireza Roostaee et al. JOURNAL OF CELLULAR PHYSIOLOGY
- TCA Cycle and Mitochondrial Membrane Potential Are Necessary for Diverse Biological Functions
- (2016) Inmaculada Martínez-Reyes et al. MOLECULAR CELL
- High-fat diet enhances stemness and tumorigenicity of intestinal progenitors
- (2016) Semir Beyaz et al. NATURE
- Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer
- (2016) Roman Camarda et al. NATURE MEDICINE
- Mitochondrial function controls intestinal epithelial stemness and proliferation
- (2016) Emanuel Berger et al. Nature Communications
- A bioassay to measure energy metabolism in mouse colonic crypts, organoids, and sorted stem cells
- (2015) Yang-Yi Fan et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis
- (2015) Kıvanç Birsoy et al. CELL
- Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells
- (2015) Lucas B. Sullivan et al. CELL
- Hepatic Mitochondrial Pyruvate Carrier 1 Is Required for Efficient Regulation of Gluconeogenesis and Whole-Body Glucose Homeostasis
- (2015) Lawrence R. Gray et al. Cell Metabolism
- Regulation of mitochondrial pyruvate uptake by alternative pyruvate carrier complexes
- (2015) T. Bender et al. EMBO JOURNAL
- Metabolic pathways promoting cancer cell survival and growth
- (2015) Lindsey K. Boroughs et al. NATURE CELL BIOLOGY
- Charting the human proteome: Understanding disease using a tissue-based atlas
- (2015) M. Uhlen et al. SCIENCE
- Regional Cell-Specific Transcriptome Mapping Reveals Regulatory Complexity in the Adult Drosophila Midgut
- (2015) Devanjali Dutta et al. Cell Reports
- c-Myc Programs Fatty Acid Metabolism and Dictates Acetyl-CoA Abundance and Fate
- (2014) Lia R. Edmunds et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Whole-mount immunostaining of the adult Drosophila gastrointestinal tract
- (2014) Craig A. Micchelli METHODS
- A Role for the Mitochondrial Pyruvate Carrier as a Repressor of the Warburg Effect and Colon Cancer Cell Growth
- (2014) John C. Schell et al. MOLECULAR CELL
- Glutamine Oxidation Maintains the TCA Cycle and Cell Survival during Impaired Mitochondrial Pyruvate Transport
- (2014) Chendong Yang et al. MOLECULAR CELL
- Regulation of Substrate Utilization by the Mitochondrial Pyruvate Carrier
- (2014) Nathaniel M. Vacanti et al. MOLECULAR CELL
- Metabolic requirements for the maintenance of self-renewing stem cells
- (2014) Keisuke Ito et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Nutrient-induced intestinal adaption and its effect in obesity
- (2014) Megan J. Dailey PHYSIOLOGY & BEHAVIOR
- Expression of Multiple Transgenes from a Single Construct Using Viral 2A Peptides in Drosophila
- (2014) Richard W. Daniels et al. PLoS One
- Transformation of intestinal stem cells into gastric stem cells on loss of transcription factor Cdx2
- (2014) Salvatore Simmini et al. Nature Communications
- Mitochondrial Pyruvate Carrier 2 Hypomorphism in Mice Leads to Defects in Glucose-Stimulated Insulin Secretion
- (2014) Patrick A. Vigueira et al. Cell Reports
- Niche-independent high-purity cultures of Lgr5+ intestinal stem cells and their progeny
- (2013) Xiaolei Yin et al. NATURE METHODS
- The UCSC Genome Browser database: 2014 update
- (2013) Donna Karolchik et al. NUCLEIC ACIDS RESEARCH
- Morphological and Molecular Characterization of Adult Midgut Compartmentalization in Drosophila
- (2013) Nicolas Buchon et al. Cell Reports
- Intestinal stem cell function in Drosophila and mice
- (2012) Huaqi Jiang et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors
- (2012) J. Wang et al. GENOME RESEARCH
- Architecture of the human regulatory network derived from ENCODE data
- (2012) Mark B. Gerstein et al. NATURE
- Factorbook.org: a Wiki-based database for transcription factor-binding data generated by the ENCODE consortium
- (2012) J. Wang et al. NUCLEIC ACIDS RESEARCH
- Identification and Functional Expression of the Mitochondrial Pyruvate Carrier
- (2012) S. Herzig et al. SCIENCE
- A Mitochondrial Pyruvate Carrier Required for Pyruvate Uptake in Yeast, Drosophila, and Humans
- (2012) D. K. Bricker et al. SCIENCE
- Metabolic trajectory of cellular differentiation in small intestine by Phasor Fluorescence Lifetime Microscopy of NADH
- (2012) Chiara Stringari et al. Scientific Reports
- The gene expression profiles of induced pluripotent stem cells from individuals with childhood cerebral adrenoleukodystrophy are consistent with proposed mechanisms of pathogenesis
- (2012) Xiao-Ming Wang et al. Stem Cell Research & Therapy
- Glycome Diagnosis of Human Induced Pluripotent Stem Cells Using Lectin Microarray
- (2011) Hiroaki Tateno et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- DNA Methylation Dynamics in Human Induced Pluripotent Stem Cells over Time
- (2011) Koichiro Nishino et al. PLoS Genetics
- The PAF Complex Synergizes with MLL Fusion Proteins at HOX Loci to Promote Leukemogenesis
- (2010) Andrew G. Muntean et al. CANCER CELL
- Identification of microRNAs expressed highly in pancreatic islet-like cell clusters differentiated from human embryonic stem cells
- (2010) Bo‑Zhi Chen et al. CELL BIOLOGY INTERNATIONAL
- The Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche
- (2010) Tugba Simsek et al. Cell Stem Cell
- Gata3 regulates trophoblast development downstream of Tead4 and in parallel to Cdx2
- (2010) A. Ralston et al. DEVELOPMENT
- Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts
- (2010) Toshiro Sato et al. NATURE
- Towards a knowledge-based Human Protein Atlas
- (2010) Mathias Uhlen et al. NATURE BIOTECHNOLOGY
- Lentiviral gene ontology (LeGO) vectors equipped with novel drug-selectable fluorescent proteins: new building blocks for cell marking and multi-gene analysis
- (2009) K Weber et al. GENE THERAPY
- Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
- (2009) Toshiro Sato et al. NATURE
- Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche
- (2009) Akifumi Ootani et al. NATURE MEDICINE
- Chromatin remodeling during mouse and human embryonic stem cell differentiation
- (2008) Jonathan L. Golob et al. DEVELOPMENTAL DYNAMICS
- Pyruvate uptake is inhibited by valproic acid and metabolites in mitochondrial membranes
- (2008) Cátia C.P. Aires et al. FEBS LETTERS
- Transcriptional and Functional Profiling of Human Embryonic Stem Cell-Derived Cardiomyocytes
- (2008) Feng Cao et al. PLoS One
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started