Endoglin prevents vascular malformation by regulating flow-induced cell migration and specification through VEGFR2 signalling

Alk1 controls arterial endothelial cell migration in lumenized vessels

(2016) Elizabeth R. Rochon et al.   DEVELOPMENT

Defective fluid shear stress mechanotransduction mediates hereditary hemorrhagic telangiectasia

(2016) Nicolas Baeyens et al.   JOURNAL OF CELL BIOLOGY

Somatic activating mutations in Pik3ca cause sporadic venous malformations in mice and humans

(2016) Sandra D. Castillo et al.   Science Translational Medicine

PI3 kinase inhibition improves vascular malformations in mouse models of hereditary haemorrhagic telangiectasia

(2016) Roxana Ola et al.   Nature Communications

Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch

(2015) Irene Maria Aspalter et al.   Nature Communications

Dynamic Endothelial Cell Rearrangements Drive Developmental Vessel Regression

(2015) Claudio A. Franco et al.   PLOS BIOLOGY

Mouse models of hereditary hemorrhagic telangiectasia: recent advances and future challenges

(2015) Simon Tual-Chalot et al.   Frontiers in Genetics

Common and Distinctive Pathogenetic Features of Arteriovenous Malformations in Hereditary Hemorrhagic Telangiectasia 1 and Hereditary Hemorrhagic Telangiectasia 2 Animal Models—Brief Report

(2014) Eva M. Garrido-Martin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Microvascular Endothelial Cells Migrate Upstream and Align Against the Shear Stress Field Created by Impinging Flow

(2014) Maggie A. Ostrowski et al.   BIOPHYSICAL JOURNAL

Deletion of Rbpj from postnatal endothelium leads to abnormal arteriovenous shunting in mice

(2014) C. M. Nielsen et al.   DEVELOPMENT

Novel Brain Arteriovenous Malformation Mouse Models for Type 1 Hereditary Hemorrhagic Telangiectasia

(2014) Eun-Jung Choi et al.   PLoS One

ENDOGLIN Is Dispensable for Vasculogenesis, but Required for Vascular Endothelial Growth Factor-Induced Angiogenesis

(2014) Zhen Liu et al.   PLoS One

Endothelial Depletion of Acvrl1 in Mice Leads to Arteriovenous Malformations Associated with Reduced Endoglin Expression

(2014) Simon Tual-Chalot et al.   PLoS One

Constitutively active Notch4 receptor elicits brain arteriovenous malformations through enlargement of capillary-like vessels

(2014) Patrick A. Murphy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arteries are formed by vein-derived endothelial tip cells

(2014) Cong Xu et al.   Nature Communications

Endosome-to-Plasma Membrane Recycling of VEGFR2 Receptor Tyrosine Kinase Regulates Endothelial Function and Blood Vessel Formation

(2014) Helen Jopling et al.   Cells

Dynamic responses of endothelial cells to changes in blood flow during vascular remodeling of the mouse yolk sac

(2013) Ryan S. Udan et al.   DEVELOPMENT

Spatial regulation of VEGF receptor endocytosis in angiogenesis

(2013) Masanori Nakayama et al.   NATURE CELL BIOLOGY

A review of contemporary options for medical management of hemangiomas, other vascular tumors, and vascular malformations

(2013) Julie Blatt et al.   PHARMACOLOGY & THERAPEUTICS

Minimal Homozygous Endothelial Deletion of Eng with VEGF Stimulation Is Sufficient to Cause Cerebrovascular Dysplasia in the Adult Mouse

(2012) Eun-Jung Choi et al.   CEREBROVASCULAR DISEASES

Stalk Cell Phenotype Depends on Integration of Notch and Smad1/5 Signaling Cascades

(2012) Iván M. Moya et al.   DEVELOPMENTAL CELL

ALK1 Signaling Inhibits Angiogenesis by Cooperating with the Notch Pathway

(2012) Bruno Larrivée et al.   DEVELOPMENTAL CELL

Bevacizumab in Patients With Hereditary Hemorrhagic Telangiectasia and Severe Hepatic Vascular Malformations and High Cardiac Output

(2012) Sophie Dupuis-Girod et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Interaction between alk1 and blood flow in the development of arteriovenous malformations

(2011) P. Corti et al.   DEVELOPMENT

Angiogenic morphogenesis driven by dynamic and heterogeneous collective endothelial cell movement

(2011) S. Arima et al.   DEVELOPMENT

Arterial-venous network formation during brain vascularization involves hemodynamic regulation of chemokine signaling

(2011) J. Bussmann et al.   DEVELOPMENT

Establishment of conditional reporter mouse lines at ROSA26 locus for live cell imaging

(2011) Takaya Abe et al.   GENESIS

Molecular control of endothelial cell behaviour during blood vessel morphogenesis

(2011) Shane P. Herbert et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Pathogenesis of Arteriovenous Malformations in the Absence of Endoglin

(2010) Marwa Mahmoud et al.   CIRCULATION RESEARCH

Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis

(2010) Yingdi Wang et al.   NATURE

Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting

(2010) Lars Jakobsson et al.   NATURE CELL BIOLOGY

Endoglin plays distinct roles in vascular smooth muscle cell recruitment and regulation of arteriovenous identity during angiogenesis

(2009) Maria L. Mancini et al.   DEVELOPMENTAL DYNAMICS

Biomechanical regulation of blood vessel growth during tissue vascularization

(2009) Witold W Kilarski et al.   NATURE MEDICINE

Regulation of multiple angiogenic pathways by Dll4 and Notch in human umbilical vein endothelial cells

(2007) Laura S. Harrington et al.   MICROVASCULAR RESEARCH