Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations

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Analysis of protein-coding genetic variation in 60,706 humans

(2016) Monkol Lek et al.   NATURE

Detecting Genetic Mosaicism in Cultures of Human Pluripotent Stem Cells

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Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt's macular dystrophy: follow-up of two open-label phase 1/2 studies

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RIKEN suspends first clinical trial involving induced pluripotent stem cells

(2015) Ken Garber   NATURE BIOTECHNOLOGY

Somatic mutation in cancer and normal cells

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Efficient CRISPR-Cas9-Mediated Generation of Knockin Human Pluripotent Stem Cells Lacking Undesired Mutations at the Targeted Locus

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Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence

(2014) Giulio Genovese et al.   NEW ENGLAND JOURNAL OF MEDICINE

Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes

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COSMIC: exploring the world's knowledge of somatic mutations in human cancer

(2014) Simon A. Forbes et al.   NUCLEIC ACIDS RESEARCH

Heterogeneity of Li-Fraumeni Syndrome links to unequal gain-of-function effects of p53 mutations

(2014) Jie Xu et al.   Scientific Reports

Human Intestinal Tissue with Adult Stem Cell Properties Derived from Pluripotent Stem Cells

(2014) Ryan Forster et al.   Stem Cell Reports

Dynamic Chromatin Remodeling Mediated by Polycomb Proteins Orchestrates Pancreatic Differentiation of Human Embryonic Stem Cells

(2013) Ruiyu Xie et al.   Cell Stem Cell

Gain of 20q11.21 in human embryonic stem cells improves cell survival by increased expression of Bcl-xL

(2013) H.T. Nguyen et al.   MOLECULAR HUMAN REPRODUCTION

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

BCL-XL Mediates the Strong Selective Advantage of a 20q11.21 Amplification Commonly Found in Human Embryonic Stem Cell Cultures

(2013) Stuart Avery et al.   Stem Cell Reports

Detecting and Estimating Contamination of Human DNA Samples in Sequencing and Array-Based Genotype Data

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High-Throughput Droplet Digital PCR System for Absolute Quantitation of DNA Copy Number

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Dynamic Changes in the Copy Number of Pluripotency and Cell Proliferation Genes in Human ESCs and iPSCs during Reprogramming and Time in Culture

(2011) Louise C. Laurent et al.   Cell Stem Cell

Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage

(2011)   NATURE BIOTECHNOLOGY

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(2011) James T Robinson et al.   NATURE BIOTECHNOLOGY

A framework for variation discovery and genotyping using next-generation DNA sequencing data

(2011) Mark A DePristo et al.   NATURE GENETICS

Chemically defined conditions for human iPSC derivation and culture

(2011) Guokai Chen et al.   NATURE METHODS

A unique chromatin signature uncovers early developmental enhancers in humans

(2010) Alvaro Rada-Iglesias et al.   NATURE

A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity

(2009) Rosa M. Marión et al.   NATURE

Two Supporting Factors Greatly Improve the Efficiency of Human iPSC Generation

(2008) Yang Zhao et al.   Cell Stem Cell

Good manufacturing practice and clinical-grade human embryonic stem cell lines

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The complete genome of an individual by massively parallel DNA sequencing

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