Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

Protein structure determination using metagenome sequence data

(2017) Sergey Ovchinnikov et al.   SCIENCE

Accurate De Novo Prediction of Protein Contact Map by Ultra-Deep Learning Model

(2017) Sheng Wang et al.   PLoS Computational Biology

Autoubiquitination of the Hrd1 Ligase Triggers Protein Retrotranslocation in ERAD

(2016) Ryan D. Baldridge et al.   CELL

CoinFold: a web server for protein contact prediction and contact-assisted protein folding

(2016) Sheng Wang et al.   NUCLEIC ACIDS RESEARCH

Crystal structure of SEL1L: Insight into the roles of SLR motifs in ERAD pathway

(2016) Hanbin Jeong et al.   Scientific Reports

Structural insight into the PTS sugar transporter EIIC

(2015) Jason G. McCoy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures

(2015) Heng Ru et al.   CELL

The TOPCONS web server for consensus prediction of membrane protein topology and signal peptides

(2015) Konstantinos D. Tsirigos et al.   NUCLEIC ACIDS RESEARCH

HMMER web server: 2015 update

(2015) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

Membrane Insertases Are Present in All Three Domains of Life

(2015) Ross E. Dalbey et al.   STRUCTURE

Large-scale determination of previously unsolved protein structures using evolutionary information

(2015) Sergey Ovchinnikov et al.   eLife

Measuring the optimal exposure for single particle cryo-EM using a 2.6 Å reconstruction of rotavirus VP6

(2015) Timothy Grant et al.   eLife

Key Steps in ERAD of Luminal ER Proteins Reconstituted with Purified Components

(2014) Alexander Stein et al.   CELL

Structural basis of Sec-independent membrane protein insertion by YidC

(2014) Kaoru Kumazaki et al.   NATURE

Robust and accurate prediction of residue–residue interactions across protein interfaces using evolutionary information

(2014) Sergey Ovchinnikov et al.   eLife

Likelihood-based classification of cryo-EM images using FREALIGN

(2013) Dmitry Lyumkis et al.   JOURNAL OF STRUCTURAL BIOLOGY

MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability

(2013) K. Katoh et al.   MOLECULAR BIOLOGY AND EVOLUTION

Der1 promotes movement of misfolded proteins through the endoplasmic reticulum membrane

(2013) Martin Mehnert et al.   NATURE CELL BIOLOGY

Quantifying the local resolution of cryo-EM density maps

(2013) Alp Kucukelbir et al.   NATURE METHODS

The genome portal of the Department of Energy Joint Genome Institute: 2014 updates

(2013) Henrik Nordberg et al.   NUCLEIC ACIDS RESEARCH

High-Resolution Comparative Modeling with RosettaCM

(2013) Yifan Song et al.   STRUCTURE

Mechanisms of Sec61/SecY-Mediated Protein Translocation Across Membranes

(2012) Eunyong Park et al.   Annual Review of Biophysics

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

HHblits: lightning-fast iterative protein sequence searching by HMM-HMM alignment

(2011) Michael Remmert et al.   NATURE METHODS

Retrotranslocation of a Misfolded Luminal ER Protein by the Ubiquitin-Ligase Hrd1p

(2010) Pedro Carvalho et al.   CELL

Jalview Version 2--a multiple sequence alignment editor and analysis workbench

(2009) A. M. Waterhouse et al.   BIOINFORMATICS

Refinement of Protein Structures into Low-Resolution Density Maps Using Rosetta

(2009) Frank DiMaio et al.   JOURNAL OF MOLECULAR BIOLOGY

Usa1 Functions as a Scaffold of the HRD-Ubiquitin Ligase

(2009) Sabine C. Horn et al.   MOLECULAR CELL

Misfolded Membrane Proteins Are Specifically Recognized by the Transmembrane Domain of the Hrd1p Ubiquitin Ligase

(2009) Brian K. Sato et al.   MOLECULAR CELL