期刊
NATURAL PRODUCT RESEARCH
卷 31, 期 14, 页码 1676-1681出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2017.1286486
关键词
Antibacterial activity; Eutypella sp; sesquiterpene lactone
资金
- National Hi-tech R&D Program of China (863 Program) [SS2012AA09160703]
- National Natural Science Foundation of China (NSFC) [41306197, 41606173]
- Guangdong Innovative Development of Marine Economy Regional Demonstration Project [GD2012-D01-001]
We isolated and identified a new sesquiterpene lactone which we named eut-Guaiane sesquiterpene (1), along with four cytochalasins from the fungus Eutypella sp. derived from the soil of high latitude of Arctic. The new structure was determined by spectroscopic studies such as 1D and 2D NMR and MS analyses, while the known compounds were identified by comparison of the NMR data with those in literatures. New compound 1 exhibited strong antibacterial activity against Escherichia coli, Bacillus subtilis and Staphylococcus aureus. Besides, it showed a little cytotoxicity against SGC7901 cell line. [GRAPHICS] .
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