Article
Chemistry, Applied
Aiping Wang, Jinge Li, Hongliang Liu, Yumei Chen, Jingming Zhou, Yankai Liu, Yanhua Qi, Wenjing Jiang, Gaiping Zhang
Summary: Direct and indirect competitive fluorescence-linked immunosorbent assays (dc-FLISA and ic-FLISA) incorporating quantum dots (QDs) as the fluorescent label were developed for detecting ASA residues in edible animal tissues. The QD-FLISA showed high sensitivity and accuracy, with limits of detection at 0.11 ng/mL and 0.001 ng/mL for dc-FLISA and ic-FLISA, respectively. The recoveries for spiked samples ranged from 80.2%-91.2% in dc-FLISA and 82.5%-91.2% in ic-FLISA, with coefficients of variations (CV) less than 12%.
FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT
(2021)
Article
Food Science & Technology
Yulou Qiu, Ajuan You, Xianshu Fu, Mingzhou Zhang, Haifeng Cui, Biao Zhang, Weiwei Qin, Zihong Ye, Xiaoping Yu
Summary: In this study, a QB-based FLISA using nanobodies was developed for the sensitive determination of Cry2A toxin in cereal. The QB-FLISA exhibited high specificity and sensitivity, and the results correlated well with those of a commercial ELISA kit.
Article
Materials Science, Multidisciplinary
Huizi Tang-Wang, Chuan Zhou, Ying Wang, Yingnan Guo, Shufang Wang, Guangsheng Fu, Baolai Liang, Yuriy I. Mazur, Morgan E. Ware, Gregory J. Salamo
Summary: In this study, InAs(Sb)/GaAs self-assembled quantum dots (QDs) with type II band alignment were successfully grown by incorporating Sb into InAs and increasing the beam equivalent pressure ratio. These InAsSb QDs exhibit different characteristics compared to the well-studied type-I InAs QDs in terms of excitation intensity, temperature dependence, and luminescence time dependence. The Sb distribution in the QDs and the wetting layer was also investigated.
Article
Chemistry, Analytical
Weijie Wu, Xinyi Liu, Mengfei Shen, Lisong Shen, Xing Ke, Daxiang Cui, Wanwan Li
Summary: A novel multicolor quantum dot nanobead-based FLISA platform has been established for highly sensitive multiplexed detection of lung cancer tumor markers. The use of multicolor QDNBs as fluorescent labels enables high detection sensitivity and construction of multiplexed fluorescent biosensors, showing potential for clinical applications.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Analytical
Daixian Wei, Jintao Liu, Zexiang Wang, Shu Zhou, Suhua Wang, Weipeng Tong, Juan Peng
Summary: The QBs-LFIA method developed in this study allows for rapid and sensitive detection of SMZ in food, with high accuracy and stability in chicken and milk samples, providing a new approach for food safety management.
Article
Nanoscience & Nanotechnology
Hong-Rae Kim, Ji-Hong Bong, Jun-Hee Park, Zhiquan Song, Min-Jung Kang, Dong Hee Son, Jae-Chul Pyun
Summary: A hypersensitive photosensor based on CsPbBr3 quantum dots was developed for chemiluminescence immunoassays, showing high sensitivity and reduced trap states, making it feasible for detecting various diseases.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Biotechnology & Applied Microbiology
Seon-Hyung Kim, Hee-Jin Jeong
Summary: This study developed a rapid and accurate detection method for a pine wilt disease biomarker. The researchers produced a recombinant minibody-type antibody against Bursaphelenchus xylophilus peroxiredoxin, which is a protein secreted by the pathogen causing the disease. They established a fluorescence-linked immunosorbent assay system using labeled minibodies, which showed high sensitivity and could be used for various fluorescence measurement techniques.
JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
(2023)
Article
Nanoscience & Nanotechnology
Yanbing Lv, Yucheng Yuan, Ning Hu, Na Jin, Dangdang Xu, Ruili Wu, Huaibin Shen, Ou Chen, Lin Song Li
Summary: This study presents a synthesis method for ultra-thick shell quantum dots and their application in C-reactive protein detection, achieving nearly a 3-fold enhancement in detection sensitivity and a 2-fold increase in shelf life. The performance improvements in protein detection are attributed to the use of core/shell quantum dots with high particle stability, high PL QYs, and a large surface area conducive to surface antibody coupling.
ACS APPLIED NANO MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Islam Seder, Ahla Jo, Bong-Hyun Jun, Sung-Jin Kim
Summary: In this study, a microfluidic platform is presented for the simple, automated, and highly sensitive immunoassay of viral antigens. By utilizing the motion of the layers and the surface tension in the liquids, reagents are able to mix homogeneously between the top and bottom chambers. The automated device achieves a highly sensitive magnetic bead-based sandwich immunoassay for the influenza A H1N1 virus within 32.5 min using magnetic beads and quantum dots.
Article
Chemistry, Physical
Jannik Rebmann, Hans Werners, Florian Johst, Marcel Dohrmann, Yannic U. Staechelin, Christian Strelow, Alf Mews, Tobias Kipp
Summary: Cation exchange occurs during the synthesis of colloidal semiconductor heteronanoparticles, affecting their band gap and optoelectronic properties. The role of cation exchange during the growth of anisotropic dot-in-rod structures was studied. The dominant process in the initial stages of the shell-growth reaction was found to be cation exchange from ZnSe to CdSe.
CHEMISTRY OF MATERIALS
(2023)
Article
Physics, Applied
Fabio del Giudice, Sergej Fust, Paul Schmiedeke, Johannes Pantle, Markus Doeblinger, Akhil Ajay, Steffen Meder, Hubert Riedl, Jonathan J. Finley, Gregor Koblmueller
Summary: This study demonstrates epitaxial InAs-AlAsSb core-shell nanowire arrays on silicon with exceptional control over internal strain close to lattice-matching and tunable band lineups between type-I and type-II, providing prospects for on-chip mid-infrared photonics and other applications like high-speed transistors and hot carrier solar cells.
APPLIED PHYSICS LETTERS
(2021)
Article
Chemistry, Multidisciplinary
Jaco J. Geuchies, Baldur Brynjarsson, Gianluca Grimaldi, Solrun Gudjonsdottir, Ward van der Stam, Wiel H. Evers, Arjan J. Houtepen
Summary: Research demonstrates that by electrochemically doping films of CdSe/CdS/ZnS QDs, quantitative control over the gain threshold can be achieved, opening up a new route for the creation of cheap, solution-processable, low-threshold QD lasers.
Article
Nanoscience & Nanotechnology
Fang Gao, Chang Lei, Yang Liu, Hao Song, Yueqi Kong, Jingjing Wan, Chengzhong Yu
Summary: This study investigates the impact of surface chemistry of dendritic mesoporous silica nanoparticles (DMSNs) on their enrichment of quantum dots (QDs) and signal amplification as label materials. The amino groups on DMSNs are found to benefit QD fluorescence preservation, while thiol groups increase QD loading capacity. Optimized DMSNs-QDs labels achieve high QD fluorescence preservation and loading capacity, enabling ultrasensitive detection of serum amyloid A (SAA).
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Medical Laboratory Technology
Jinsong Tang, Lili Wu, Jingtao Lin, Erying Zhang, Yong Luo
Summary: The study successfully developed a QD-based LFIA strip for rapid and accurate detection of IL-6 levels, with a linear range of 10-4000 pg/ml, sensitivity of 1.995 pg/ml, and high accuracy and precision.
JOURNAL OF CLINICAL LABORATORY ANALYSIS
(2021)
Article
Chemistry, Analytical
Chung-An Chen, Ping-Yeh Chiu, Tse-Hao Huang, Natalie Yi-Ju Ho, Fu-Cheng Kao, Tsung-Ting Tsai
Summary: Appropriate follow-up after treatment initiation in patients with osteoporosis is challenging. Serum biomarkers, such as procollagen type I propeptide (PINP), can provide clinically useful information for disease management. However, rapid and cost-effective methods for detecting serum PINP are lacking. In this study, we developed a high-sensitivity lateral flow immunoassay with a stacking pad (sLFIA) for quantitative detection of PINP and found that it can serve as a point-of-care test (POCT) for monitoring medication response and managing osteoporosis.
ANALYTICA CHIMICA ACTA
(2023)
