Article
Chemistry, Multidisciplinary
Jin Wang, Yinhang Jia, Qiyue Wang, Zeyu Liang, Guangxu Han, Zejun Wang, Jiyoung Lee, Meng Zhao, Fangyuan Li, Ruiliang Bai, Daishun Ling
Summary: The article introduces a T-1-T-2 dual-mode contrast agent designed for ultrahigh-field MRI, which not only improves resolution and signal-to-noise ratio, but also effectively displays microvasculature structures with high sensitivity and accuracy in detecting tumor vascular permeability.
ADVANCED MATERIALS
(2021)
Review
Chemistry, Multidisciplinary
Mike Jeon, Mackenzie Halbert, Zachary R. Stephen, Miqin Zhang
Summary: Gadolinium-based chelates are commonly used contrast agents for MRI, but their toxicity and potential retention in patients' bodies have raised safety concerns. Iron oxide nanoparticles have emerged as a promising alternative due to their non-toxic and biodegradable nature, but their development as T-1 contrast agents is complex and challenging. Progress is being made in exploring IONPs as safe and improved alternatives, but there are still many hurdles to overcome before they can be used clinically.
ADVANCED MATERIALS
(2021)
Article
Oncology
Wlla E. Al-Hammad, Mamiko Fujikura, Miki Hisatomi, Shunsuke Okada, Luciana Munhoz, Toshiyuki Kawazu, Yohei Takeshita, Mariko Fujita, Yoshinobu Yanagi, Jun-Ichi Asaumi
Summary: The aim of this study was to develop a diagnostic approach for vascular anomalies (VAs) in the oral and maxillofacial region based on CT, MRI, and DCE-MRI. The results showed that MRI was more sensitive in detecting VAs, while CT was better in detecting phleboliths. VAs showed homogeneous isodensity on CT and heterogeneous hyperdensity on CE-CT. VAs also exhibited heterogeneous high signal intensity on T1WI, short tau inversion recovery MRI, and fat-saturated CE-T1WI. The CI curves of VAs had a specific pattern, which could aid radiologists in diagnosing VAs. The findings indicated DCE-MRI as a useful tool for the diagnosis of VAs.
Article
Biochemical Research Methods
Deeksha M. Sankepalle, Brian Anthony, Srivalleesha Mallidi
Summary: This study developed a portable handheld device for 3D ultrasound and photoacoustic imaging using a low-cost visual odometry system. The device successfully tracked hand movements and accurately detected step sizes of 500 μm. The results demonstrated the potential of using off-the-shelf technology for freehand 3D USPA imaging.
BIOMEDICAL OPTICS EXPRESS
(2023)
Review
Nanoscience & Nanotechnology
Ghazaleh Jamalipour Soufi, Ali Hekmatnia, Siavash Iravani, Rajender S. Varma
Summary: Magnetic resonance imaging (MRI) is a widely used noninvasive clinical imaging modality in bio- and nanomedicine, especially for tumor detection and high-quality three-dimensional imaging. The design of efficient nanoscale contrast agents (NCAs) is crucial for specific detection and imaging of tumors. However, there are still challenges to be addressed in the clinical applications of these agents, including nanotoxicology and biosafety issues.
ACS APPLIED NANO MATERIALS
(2022)
Review
Chemistry, Physical
Arash Farhadi, Felix Sigmund, Gil Gregor Westmeyer, Mikhail G. Shapiro
Summary: Advancements in research have allowed for the visualization of specific cell and molecular functions in non-invasive biological imaging using genetically encoded protein contrast agents, providing new forms of biomolecular and cellular contrast.
Review
Chemistry, Physical
Huan Zhang, Xiao Li Liu, Hai Ming Fan
Summary: Magnetic resonance imaging (MRI) has revolutionized medical imaging diagnostics. However, the clinical use of Gd-based contrast agents (CAs) still has limitations, making the development of magnetic nanoparticle-based CAs a promising avenue for research.
Article
Chemistry, Multidisciplinary
Bo Song, Xinyue Zhang, Xinyi Wen, Qi Liu, Hua Ma, Weihua Guo, Mingqian Tan, Lei Jia, Jingli Yuan
Summary: The study developed a novel bioconjugate, Tf-Eu-Gd, with intense long-lived luminescence, high MR relaxivity, and good biocompatibility. As a probe, Tf-Eu-Gd can specifically accumulate in cancer cells overexpressing Tf receptors for TGL and MR imaging of tumors.
NEW JOURNAL OF CHEMISTRY
(2021)
Review
Engineering, Biomedical
Shengxiang Fu, Zhongyuan Cai, Hua Ai
Summary: MRI is commonly used for disease diagnosis, and the development of stimulus-responsive contrast agents provides new opportunities to overcome the limitations of traditional contrast agents. By tuning the structural features of contrast agents, optimization of the T(1) and T(2) relaxation properties can be achieved, thereby improving the sensitivity and specificity of the contrast agents.
ADVANCED HEALTHCARE MATERIALS
(2021)
Article
Multidisciplinary Sciences
Shulong Wang, Liangliang Zhang, Jingjin Zhao, Min He, Yong Huang, Shulin Zhao
Summary: The study found that the GSH level significantly increases in tumor tissues, thus it can be used as an endogenous molecule for diagnosing and treating tumors. The Fe-Cu@PANI nanoparticles prepared in the study utilize the tumor microenvironment-induced properties to activate tumor photoacoustic imaging and photothermal therapy in vivo, enhancing the efficiency of treatment.
Article
Biochemical Research Methods
Junwei Liu, Lulu Liu, Saisi Qu, Tongtong Zhang, Danyang Wang, Qinghua Ji, Tian Wang, Hongyu Shi, Kaichen Song, Weijia Fang, Wei Chen, Weiwei Yin
Summary: This study identified the impact of Gd contamination on CyTOF data quality, and developed a computational method named GdClean to effectively remove Gd contamination signals while preserving the real signals.
Review
Chemistry, Multidisciplinary
Jie Lv, Shubham Roy, Miao Xie, Xiulan Yang, Bing Guo
Summary: In recent times, MRI has emerged as a highly promising modality for diagnosing severe diseases due to its exceptional resolution and ease of use. However, low contrast remains a challenge for MRI, requiring the use of contrast agents (CAs). Scientists have made significant efforts to enhance precision by combining MRI with other imaging techniques and modifying CAs. This work focuses on the rational design of CAs and optimizing their compatibility for multimodal imaging and intelligent applications.
Review
Biotechnology & Applied Microbiology
Danping Zhuang, Huifen Zhang, Genwen Hu, Bing Guo
Summary: This review summarizes the recent advances in MRI contrast agents and dual-modal or triple-modal nanoprobes for glioblastoma (GBM) imaging, and discusses potential obstacles and prospects for future research and clinical translation of these contrast agents.
JOURNAL OF NANOBIOTECHNOLOGY
(2022)
Article
Veterinary Sciences
Michaela Gumpenberger, Silvana Schmidt-Ukaj, Stephan Handschuh
Summary: This study focuses on the techniques and interpretation of radiography, computed tomography, and sonography in visually displaying various organs within the mantle cavity of Giant African land snails (GALS).
FRONTIERS IN VETERINARY SCIENCE
(2023)
Article
Biotechnology & Applied Microbiology
Sahar Rakhshan, Diego Alberti, Rachele Stefania, Valeria Bitonto, Simonetta Geninatti Crich
Summary: LDLs are selectively taken up by tumor cells and can be successfully used for the selective delivery of Paclitaxel and imaging agents. For the first time, the non-invasive in vivo determination of the amount of PTX accumulated in the tumor was possible, thanks to the use of theranostic agents of natural origin.
JOURNAL OF NANOBIOTECHNOLOGY
(2021)
Article
Multidisciplinary Sciences
Ilaria Vicenti, Filippo Dragoni, Alessia Giannini, Anna Casabianca, Francesca Lombardi, Laura Di Sante, Ombretta Turriziani, Sara Racca, Stefania Paolucci, Alessia Lai, Isabella Bon, Isabella Abbate, Gabriella Rozera, Simone Belmonti, Rossana Scutari, Claudia Alteri, Francesco Saladini, Maurizio Zazzi
Summary: This study aimed to validate the quantification methods for HIV-1 DNA. The results showed excellent performance in detecting HIV-1 DNA standards, but improvement is needed for the detection of different HIV-1 subtypes.
SCIENTIFIC REPORTS
(2022)
Article
Astronomy & Astrophysics
A. Marinucci, F. Muleri, M. Dovciak, S. Bianchi, F. Marin, G. Matt, F. Ursini, R. Middei, H. L. Marshall, L. Baldini, T. Barnouin, N. Cavero Rodriguez, A. De Rosa, L. Di Gesu, D. Harper, A. Ingram, V Karas, H. Krawczynski, G. Madejski, C. Panagiotou, P. O. Petrucci, J. Podgorny, S. Puccetti, F. Tombesi, A. Veledina, W. Zhang, I Agudo, L. A. Antonelli, M. Bachetti, W. H. Baumgartner, R. Bellazzini, S. D. Bongiorno, R. Bonino, A. Brez, N. Bucciantini, F. Capitanio, S. Castellano, E. Cavazzuti, S. Ciprini, E. Costa, E. Del Monte, N. Di Lalla, A. Di Marco, I Donnarumma, V Doroshenko, S. R. Ehlert, T. Enoto, Y. Evangelista, S. Fabiani, R. Ferrazzoli, J. A. Garcia, S. Gunji, K. Hayashida, J. Heyl, W. Iwakiri, S. G. Jorstad, T. Kitaguchi, J. J. Kolodziejczak, F. La Monaca, L. Latronico, I Liodakis, S. Maldera, A. Manfreda, A. P. Marscher, I Mitsuishi, T. Mizuno, C-Y Ng, S. L. O'Dell, N. Omodei, C. Oppedisano, A. Papitto, G. G. Pavlov, A. L. Peirson, M. Perri, M. Pesce-Rollins, M. Pilia, A. Possenti, J. Poutanen, B. D. Ramsey, J. Rankin, A. Ratheesh, R. W. Romani, C. Sgrs, P. Slane, P. Soffitta, G. Spandre, T. Tamagawa, F. Tavecchio, R. Taverna, Y. Tawara, A. F. Tennant, N. E. Thomas, A. Trois, S. S. Tsygankov, R. Turolla, J. Vink, M. C. Weisskopf, K. Wu, F. Xie, S. Zane
Summary: We report the first observation of a radio-quiet active galactic nucleus (AGN) in polarized X-rays, which was observed in the Seyfert 1.9 galaxy MCG-05-23-16. The analysis of the observation data revealed some characteristics of this phenomenon, such as the polarization degree and the broad-band spectrum. Comparisons with simulations further enhance our understanding of this phenomenon.
MONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY
(2022)
Article
Astronomy & Astrophysics
Fiamma Capitanio, Sergio Fabiani, Andrea Gnarini, Francesco Ursini, Carlo Ferrigno, Giorgio Matt, Juri Poutanen, Massimo Cocchi, Romana Mikusincova, Ruben Farinelli, Stefano Bianchi, Jari J. E. Kajava, Fabio Muleri, Celia Sanchez-Fernandez, Paolo Soffitta, Kinwah Wu, Ivan Agudo, Lucio A. Antonelli, Matteo Bachetti, Luca Baldini, Wayne H. Baumgartner, Ronaldo Bellazzini, Stephen D. Bongiorno, Raffaella Bonino, Alessandro Brez, Niccolo Bucciantini, Simone Castellano, Elisabetta Cavazzuti, Stefano Ciprini, Enrico Costa, Alessandra De Rosa, Ettore Del Monte, Laura Di Gesu, Niccolo Di Lalla, Alessandro Di Marco, Immacolata Donnarumma, Victor Doroshenko, Michal Dovciak, Steven R. Ehlert, Teruaki Enoto, Yuri Evangelista, Riccardo Ferrazzoli, Javier A. Garcia, Shuichi Gunji, Kiyoshi Hayashida, Jeremy Heyl, Wataru Iwakiri, Svetlana G. Jorstad, Vladimir Karas, Takao Kitaguchi, Jeffery J. Kolodziejczak, Henric Krawczynski, Fabio La Monaca, Luca Latronico, Ioannis Liodakis, Simone Maldera, Alberto Manfreda, Frederic Marin, Andrea Marinucci, Alan P. Marscher, Herman L. Marshall, Ikuyuki Mitsuishi, Tsunefumi Mizuno, C. -Y. Ng, Stephen L. O'Dell, Nicola Omodei, Chiara Oppedisano, Alessandro Papitto, George G. Pavlov, Abel L. Peirson, Matteo Perri, Melissa Pesce-Rollins, Pierre-Olivier Petrucci, Maura Pilia, Andrea Possenti, Simonetta Puccetti, Brian D. Ramsey, John Rankin, Ajay Ratheesh, Roger W. Romani, Carmelo Sgro, Patrick Slane, Gloria Spandre, Toru Tamagawa, Fabrizio Tavecchio, Roberto Taverna, Yuzuru Tawara, Allyn F. Tennant, Nicholas E. Thomas, Francesco Tombesi, Alessio Trois, Sergey S. Tsygankov, Roberto Turolla, Jacco Vink, Martin C. Weisskopf, Fei Xie, Silvia Zane
Summary: The launch of IXPE on December 9, 2021 has provided a new perspective in X-ray astronomy. In this study, we present the first observation results of GS 1826-238, a weakly magnetized neutron star, using IXPE on March 29-31, 2022. The upper limit of linear polarization degree (99.73% confidence level) is found to be 1.3% in the energy range of 2-8 keV. Coordinated observations with INTEGRAL and NICER were conducted simultaneously to constrain the geometry and inclination angle of GS 1826-238.
ASTROPHYSICAL JOURNAL
(2023)
Article
Astronomy & Astrophysics
Riccardo Middei, Ioannis Liodakis, Matteo Perri, Simonetta Puccetti, Elisabetta Cavazzuti, Laura Di Gesu, Steven R. Ehlert, Grzegorz Madejski, Alan P. Marscher, Herman L. Marshall, Fabio Muleri, Michela Negro, Svetlana G. Jorstad, Beatriz Agis-Gonzalez, Ivan Agudo, Giacomo Bonnoli, Maria Bernardos, Victor Casanova, Maya Garcia-Comas, Cesar Husillos, Alessandro Marchini, Alfredo Sota, Pouya M. Kouch, Elina Lindfors, George A. Borman, Evgenia N. Kopatskaya, Elena G. Larionova, Daria A. Morozova, Sergey S. Savchenko, Andrey A. Vasilyev, Alexey Zhovtan, Carolina Casadio, Juan Escudero, Ioannis Myserlis, Antonio Hales, Seiji Kameno, Ruediger Kneissl, Hugo Messias, Hiroshi Nagai, Dmitry Blinov, Ioakeim G. Bourbah, Sebastian Kiehlmann, Evangelos Kontopodis, Nikos Mandarakas, Stylianos Romanopoulos, Raphael Skalidis, Anna Vervelaki, Joseph R. Masiero, Dimitri Mawet, Maxwell A. Millar-Blanchaer, Georgia Panopoulou, Samaporn Tinyanont, Andrei Berdyugin, Masato Kagitani, Vadim Kravtsov, Takeshi Sakanoi, Ryo Imazawa, Mahito Sasada, Yasushi Fukazawa, Koji S. Kawabata, Makoto Uemura, Tsunefumi Mizuno, Tatsuya Nakaoka, Hiroshi Akitaya, Mark Gurwell, Ramprasad Rao, Niccolo Di Lalla, Nicolo Cibrario, Immacolata Donnarumma, Dawoon E. Kim, Nicola Omodei, Luigi Pacciani, Juri Poutanen, Fabrizio Tavecchio, Lucio A. Antonelli, Matteo Bachetti, Luca Baldini, Wayne H. Baumgartner, Ronaldo Bellazzini, Stefano Bianchi, Stephen D. Bongiorno, Raffaella Bonino, Alessandro Brez, Niccolo Bucciantini, Fiamma Capitanio, Simone Castellano, Stefano Ciprini, Enrico Costa, Alessandra De Rosa, Ettore Del Monte, Alessandro Di Marco, Victor Doroshenko, Michal Dovciak, Teruaki Enoto, Yuri Evangelista, Sergio Fabiani, Riccardo Ferrazzoli, Javier A. Garcia, Shuichi Gunji, Kiyoshi Hayashida, Jeremy Heyl, Wataru Iwakiri, Vladimir Karas, Takao Kitaguchi, Jeffery J. Kolodziejczak, Henric Krawczynski, Fabio La Monaca, Luca Latronico, Simone Maldera, Alberto Manfreda, Frederic Marin, Andrea Marinucci, Francesco Massaro, Giorgio Matt, Ikuyuki Mitsuishi, C-Y Ng, Stephen L. O'Dell, Chiara Oppedisano, Alessandro Papitto, George G. Pavlov, Abel L. Peirson, Melissa Pesce-Rollins, Pierre-Olivier Petrucci, Maura Pilia, Andrea Possenti, Brian D. Ramsey, John Rankin, Ajay Ratheesh, Roger W. Romani, Carmelo Sgro, Patrick Slane, Paolo Soffitta, Gloria Spandre, Toru Tamagawa, Roberto Taverna, Yuzuru Tawara, Allyn F. Tennant, Nicholas E. Thomas, Francesco Tombesi, Alessio Trois, Sergey Tsygankov, Roberto Turolla, Jacco Vink, Martin C. Weisskopf, Kinwah Wu, Fei Xie, Silvia Zane
Summary: A multiwavelength polarization analysis of BL Lacertae suggests that proton-synchrotron radiation does not significantly contribute to its X-ray emission, providing support for a leptonic origin.
ASTROPHYSICAL JOURNAL LETTERS
(2023)
Article
Biochemistry & Molecular Biology
Alessandra Fraternale, Marta De Angelis, Riccardo De Santis, Donatella Amatore, Sofia Masini, Francesca Monittola, Michele Menotta, Federica Biancucci, Francesca Bartoccini, Michele Retini, Valentina Fiori, Raoul Fioravanti, Fabio Magurano, Laura Chiarantini, Florigio Lista, Giovanni Piersanti, Anna T. Palamara, Lucia Nencioni, Mauro Magnani, Rita Crinelli
Summary: The life cycle of SARS-CoV-2 is influenced by the environmental redox state, with a reducing environment impairing spike protein binding to ACE2 and an oxidizing environment promoting their interaction. Synthetic low molecular weight thiols induce a more reduced state in the receptor binding domain of the spike protein, impairing ACE2 binding and interfering with protein folding and viral replication. These thiols could potentially serve as innovative anti-SARS-CoV-2 therapeutics.
Review
Pharmacology & Pharmacy
Sara Biagiotti, Faiza Abbas, Mariele Montanari, Chiara Barattini, Luigia Rossi, Mauro Magnani, Stefano Papa, Barbara Canonico
Summary: This article provides an overview of extracellular vesicles (EVs) nature, features, methodologies for isolation/preparation, and characterization/visualization. EVs have extensive applications in nanomedical-drug delivery and regenerative medicine, offering advantages over synthetic vehicles or nanoparticles. The article particularly focuses on red blood cell-derived extracellular vesicles (RBCEVs), discussing their biogenesis, isolation/production methods, and therapeutic applications. RBCEVs show promise as a versatile platform for clinical applications and pharmaceutical exploitations.
Article
Biochemistry & Molecular Biology
Antonella Antonelli, Emanuele Salvatore Scarpa, Santina Bruzzone, Cecilia Astigiano, Francesco Piacente, Michela Bruschi, Alessandra Fraternale, Christian A. A. Di Buduo, Alessandra Balduini, Mauro Magnani
Summary: Sinusoidal endothelial cells in the bone marrow play a crucial role in supporting the hematopoietic stem and progenitor cells by providing necessary signals for their self-renewal, survival, and differentiation. However, the low oxygen tension in the bone marrow affects these functions. In this study, we investigated how endothelial cells respond to a decrease in oxygen levels and found that the expression of certain genes involved in intercellular communication is regulated by SIRT6 under extreme hypoxic conditions.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Cecilia Astigiano, Francesco Piacente, Maria Elena Laugieri, Andrea Benzi, Christian A. A. Di Buduo, Carolina P. P. Miguel, Debora Soncini, Michele Cea, Antonella Antonelli, Mauro Magnani, Alessandra Balduini, Antonio De Flora, Santina Bruzzone
Summary: SIRT6, a member of the sirtuin family, plays an emerging role in anti-inflammatory processes in various diseases and cell types, including endothelial cells. Overexpression of SIRT6 in human umbilical vein endothelial cells (SIRT6+ HUVECs) was found to affect adhesion molecule levels and promote megakaryocyte proliferation and proplatelet formation. Furthermore, the pro-inflammatory activation of the ATP/purinergic axis was reduced in SIRT6+ HUVECs.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Virology
Chiara Orlandi, Giuseppe Stefanetti, Simone Barocci, Gloria Buffi, Aurora Diotallevi, Ettore Rocchi, Marcello Ceccarelli, Sara Peluso, Daniela Vandini, Eugenio Carlotti, Mauro Magnani, Luca Galluzzi, Anna Casabianca
Summary: The humoral response after vaccination was compared in individuals who received different COVID-19 vaccine schedules. Heterologous vaccination induced a stronger immune response than the two homologous vaccinations. The ChAd/BNT vaccine schedule exhibited the longest time of anti-S IgG negativization and slow decay of the titer over time. Factors such as vaccine schedule and BMI had a significant impact on the immune response.
Article
Infectious Diseases
Marilena Agosta, Daniela Bencardino, Marta Argentieri, Laura Pansani, Annamaria Sisto, Marta Luisa Ciofi Degli Atti, Carmen D'Amore, Pietro Bagolan, Barbara Daniela Iacobelli, Mauro Magnani, Massimiliano Raponi, Carlo Federico Perno, Francesca Andreoni, Paola Bernaschi
Summary: A rapid and unexpected spread of NDM-1 carbapenemase-producing Klebsiella pneumoniae and Escherichia coli cases were reported in a neonatal surgical unit in Rome, Italy. A total of 20 strains (8 K. pneumoniae and 12 E. coli) with NDM-1 gene were isolated from 17 out of 230 stool samples collected from neonates admitted in the ward. Infection control interventions prevented the dissemination of the strains in the ward.
Article
Construction & Building Technology
Francesco Palma, Giulia Baldelli, Giulia Amagliani, Mattia Paolo Aliano, Mauro Magnani, Giorgio Brandi, Giuditta Fiorella Schiavano
Summary: The beneficial effects of physical activity may be compromised by reduced indoor air quality in confined sports environments. However, the use of UV-C LED technology can significantly reduce the airborne microbial load and provide hygienic and ecological advantages. A new eco-friendly technology called 'CSA System technology' was integrated into an innovative continuous sanitation air device and demonstrated high efficacy in eliminating airborne microorganisms, making it a promising solution for efficient and healthy sanitation in indoor sports environments.
INDOOR AND BUILT ENVIRONMENT
(2023)
Article
Biochemistry & Molecular Biology
Federica De Castro, Erika Stefano, Francesco Paolo Fanizzi, Riccardo Di Corato, Pasant Abdalla, Francesca Luchetti, Maria Gemma Nasoni, Rosaria Rinaldi, Mauro Magnani, Michele Benedetti, Antonella Antonelli
Summary: This study evaluated the feasibility of loading platinum-based nucleoside derivatives into human red blood cells and found that these complexes are stable and suitable for incorporation. This opens up new possibilities for incorporating other metalated nucleobase analogues with potential antitumor and/or antiviral activity into red blood cells.
Article
Chemistry, Multidisciplinary
Tania Vanzolini, Tomas Di Mambro, Mauro Magnani, Michele Menotta
Summary: Fungal infections, especially in immunocompromised individuals, are a growing concern due to the rise of drug resistance. The Candida genus, particularly C. auris, poses a severe threat to public health. H5K1, a monoclonal antibody, has shown potential in targeting Candida species, especially C. auris, when combined with existing antifungal drugs. Atomic force microscopy (AFM) was used to assess the effects of H5K1, alone and in combination with other drugs, on C. auris cells, revealing its role in perturbing the fungal cell wall and altering its composition, stiffness, and roughness.
Proceedings Paper
Astronomy & Astrophysics
Saverio Lombardi, Fabrizio Lucarelli, Ciro Bigongiari, Stefano Gallozzi, Martina Cardillo, Michele Mastropietro, Francesco Gabriele Saturni, Francesco Visconti, Lucio Angelo Antonelli, Andrea Bulgarelli, Milvia Capalbi, Osvaldo Catalano, Antonio Alessio Compagnino, Vito Conforti, Silvia Crestan, Giancarlo Cusumano, Antonino D'Ai, Stefano Germani, Andrea Giuliani, Simone Iovenitti, Valentina La Parola, Maria Concetta Maccarone, Teresa Mineo, Davide Mollica, Antonio Pagliaro, Nicolo Parmiggiani, Matteo Perri, Fabio Pintore, Salvatore Scuderi, Gino Tosti, Stefano Vercellone, Luca Zampieri
Summary: ASTRI Mini-Array is an international project to build and operate a array of nine 4-m class Imaging Atmospheric Cherenkov Telescopes for deep observations of gamma rays. The project aims to achieve effective handling and scientific exploitation of the data through dedicated systems for Data Processing, Simulation, and Archive. The raw data will be processed and analyzed to generate final scientific products, and detailed simulated data will be used for precise reconstruction and background rejection. The Archive System will provide data access at different user levels and for different use cases.
SOFTWARE AND CYBERINFRASTRUCTURE FOR ASTRONOMY VII
(2022)
Proceedings Paper
Astronomy & Astrophysics
A. Bulgarelli, F. Lucarelli, G. Tosti, V Conforti, N. Parmiggiani, J. H. Schwarz, L. A. Antonelli, L. Baroncelli, C. Bigongiari, M. Capalbi, M. Cardillo, G. A. R. Castillo, O. Catalano, A. A. Compagnino, M. Corpora, A. Costa, S. Crestan, G. Cusumano, A. D'Ai, V Fioretti, S. Gallozzi, S. Germani, F. Gianotti, V Giordano, A. Giuliani, P. G. Bruno, J. G. Green, A. Grillo, F. Incardona, S. Iovenitti, N. La Palombara, V La Parola, M. Landoni, S. Lombardi, M. C. Maccarone, R. Millul, T. Mineo, D. Mollica, A. Pagliaro, G. Pareschi, V Pastore, M. Perri, F. Pintore, P. Romano, F. Russo, P. Sangiorgi, F. G. Saturni, E. Sciacca, S. Scuderi, A. Tacchini, V Testa, M. Trifoglio, A. Tutone, S. Vercellone
Summary: The ASTRI Mini-Array is an international collaboration project focused on very-high gamma-ray astronomy. It utilizes an array of 9 telescopes and high-speed networking connection for remote operations and data processing.
SOFTWARE AND CYBERINFRASTRUCTURE FOR ASTRONOMY VII
(2022)