Striatal D1 medium spiny neuron activation induces dyskinesias in parkinsonian mice

Selective Inactivation of Striatal FosB/ΔFosB-Expressing Neurons Alleviates L-DOPA–Induced Dyskinesia

(2016) Michel Engeln et al.   BIOLOGICAL PSYCHIATRY

L-DOPA Oppositely Regulates Synaptic Strength and Spine Morphology in D1 and D2 Striatal Projection Neurons in Dyskinesia

(2016) Luz M Suarez et al.   CEREBRAL CORTEX

Optogenetic activation of striatal cholinergic interneurons regulates L-dopa-induced dyskinesias

(2016) Tanuja Bordia et al.   NEUROBIOLOGY OF DISEASE

Dopamine D3 Receptor Modulates l-DOPA-Induced Dyskinesia by Targeting D1 Receptor-Mediated Striatal Signaling

(2015) Oscar Solís et al.   CEREBRAL CORTEX

Balancing the basal ganglia circuitry: A possible new role for dopamine D2 receptors in health and disease

(2015) Maxime Cazorla et al.   MOVEMENT DISORDERS

Loss of Striatonigral GABAergic Presynaptic Inhibition Enables Motor Sensitization in Parkinsonian Mice

(2015) Anders Borgkvist et al.   NEURON

Evidence for a role for α6∗ nAChRs in l-dopa-induced dyskinesias using parkinsonian α6∗ nAChR gain-of-function mice

(2015) T. Bordia et al.   NEUROSCIENCE

Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson's disease

(2015) Matthieu F. Bastide et al.   PROGRESS IN NEUROBIOLOGY

Direct and indirect pathways of basal ganglia: a critical reappraisal

(2014) Paolo Calabresi et al.   NATURE NEUROSCIENCE

Selective loss of bi-directional synaptic plasticity in the direct and indirect striatal output pathways accompanies generation of parkinsonism and l-DOPA induced dyskinesia in mouse models

(2014) Sherri L. Thiele et al.   NEUROBIOLOGY OF DISEASE

Cellular and Behavioral Outcomes of Dorsal Striatonigral Neuron Ablation: New Insights into Striatal Functions

(2014) Delphine Révy et al.   NEUROPSYCHOPHARMACOLOGY

Cell type-specific plasticity of striatal projection neurons in parkinsonism and L-DOPA-induced dyskinesia

(2014) Tim Fieblinger et al.   Nature Communications

Multiple CNS nicotinic receptors mediate l-dopa-induced dyskinesias: Studies with parkinsonian nicotinic receptor knockout mice

(2013) Maryka Quik et al.   BIOCHEMICAL PHARMACOLOGY

L-DOPA Treatment Selectively Restores Spine Density in Dopamine Receptor D2–Expressing Projection Neurons in Dyskinetic Mice

(2013) Luz M. Suárez et al.   BIOLOGICAL PSYCHIATRY

Control of Basal Ganglia Output by Direct and Indirect Pathway Projection Neurons

(2013) B. S. Freeze et al.   JOURNAL OF NEUROSCIENCE

Concurrent activation of striatal direct and indirect pathways during action initiation

(2013) Guohong Cui et al.   NATURE

Oleoylethanolamide reduces L-DOPA-induced dyskinesia via TRPV1 receptor in a mouse model of Parkinson´s disease

(2013) Ramiro González-Aparicio et al.   NEUROBIOLOGY OF DISEASE

α4β2 nicotinic receptors play a role in the nAChR-mediated decline in l-dopa-induced dyskinesias in parkinsonian rats

(2013) Maryka Quik et al.   NEUROPHARMACOLOGY

Phosphodiesterase 10A controls D1-mediated facilitation of GABA release from striato-nigral projections under normal and dopamine-depleted conditions

(2013) Dalila Mango et al.   NEUROPHARMACOLOGY

Rebalance of Striatal NMDA/AMPA Receptor Ratio Underlies the Reduced Emergence of Dyskinesia During D2-Like Dopamine Agonist Treatment in Experimental Parkinson's Disease

(2012) V. Bagetta et al.   JOURNAL OF NEUROSCIENCE

Differential regulation of motor control and response to dopaminergic drugs by D1R and D2R neurons in distinct dorsal striatum subregions

(2011) Pierre F Durieux et al.   EMBO JOURNAL

Nicotine Reduces L-DOPA-Induced Dyskinesias by Acting at  2* Nicotinic Receptors

(2011) L. Z. Huang et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

In vivo evidence for a differential contribution of striatal and nigral D1 and D2 receptors to l-DOPA induced dyskinesia and the accompanying surge of nigral amino acid levels

(2011) Flora Mela et al.   NEUROBIOLOGY OF DISEASE

Striatal Signaling in L-DOPA-Induced Dyskinesia: Common Mechanisms with Drug Abuse and Long Term Memory Involving D1 Dopamine Receptor Stimulation

(2011) Mario Gustavo Murer et al.   Frontiers in Neuroanatomy

L-DOPA-Induced Dyskinesia and Abnormal Signaling in Striatal Medium Spiny Neurons: Focus on Dopamine D1 Receptor-Mediated Transmission

(2011) Michael Feyder et al.   Frontiers in Behavioral Neuroscience

Regulation of parkinsonian motor behaviours by optogenetic control of basal ganglia circuitry

(2010) Alexxai V. Kravitz et al.   NATURE

Altered function of glutamatergic cortico-striatal synapses causes output pathway abnormalities in a chronic model of parkinsonism

(2010) Ruth Warre et al.   NEUROBIOLOGY OF DISEASE

l-DOPA-induced dyskinesia in hemiparkinsonian rats is associated with up-regulation of adenylyl cyclase type V/VI and increased GABA release in the substantia nigra reticulata

(2010) Claudia Rangel-Barajas et al.   NEUROBIOLOGY OF DISEASE

Genetic Inactivation of Dopamine D1 but Not D2 Receptors Inhibits L-DOPA–Induced Dyskinesia and Histone Activation

(2009) Sanja Darmopil et al.   BIOLOGICAL PSYCHIATRY

Pharmacological Analysis Demonstrates Dramatic Alteration of D1 Dopamine Receptor Neuronal Distribution in the Rat Analog of L-DOPA-Induced Dyskinesia

(2009) A. Berthet et al.   JOURNAL OF NEUROSCIENCE

Evaluation of D2 and D3 dopamine receptor selective compounds on l-dopa-dependent abnormal involuntary movements in rats

(2009) Rakesh Kumar et al.   NEUROPHARMACOLOGY

Differential Involvement of D1 and D2 Dopamine Receptors in L-DOPA-Induced Angiogenic Activity in a Rat Model of Parkinson's Disease

(2009) Hanna S Lindgren et al.   NEUROPSYCHOPHARMACOLOGY

Inhibition of mTOR Signaling in Parkinson's Disease Prevents L-DOPA-Induced Dyskinesia

(2009) E. Santini et al.   Science Signaling

Cabergoline and pramipexole fail to modify already established dyskinesias in an animal model of parkinsonism

(2008) Celia Larramendy et al.   BEHAVIOURAL BRAIN RESEARCH

l-DOPA activates ERK signaling and phosphorylates histone H3 in the striatonigral medium spiny neurons of hemiparkinsonian mice

(2008) Emanuela Santini et al.   JOURNAL OF NEUROCHEMISTRY

Recurrent Collateral Connections of Striatal Medium Spiny Neurons Are Disrupted in Models of Parkinson's Disease

(2008) S. Taverna et al.   JOURNAL OF NEUROSCIENCE

Striatal Plasticity and Basal Ganglia Circuit Function

(2008) Anatol C. Kreitzer et al.   NEURON

Dichotomous Dopaminergic Control of Striatal Synaptic Plasticity

(2008) W. Shen et al.   SCIENCE