4.6 Article

Chemical Constituents of Murraya tetramera Huang and Their Repellent Activity against Tribolium castaneum

期刊

MOLECULES
卷 22, 期 8, 页码 -

出版社

MDPI
DOI: 10.3390/molecules22081379

关键词

T. castaneum; M. tetramera; repellent activity; grey relational analysis; chemical constituents

资金

  1. National Key Research and Development Program [2016YFC0500805]
  2. National Natural Science Foundation of China [81403184]

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Sixteen compounds were isolated from the leaves and stems of Murraya tetramera Huang. Based on the NMR and MS spectral results, the structures were determined. It was confirmed that the isolated compounds included three new compounds (9, 10 and 13) and one new natural product (8), which were identified asmurratetra A (9), murratetra B (10), murratetra C (13) and [2-(7-methoxy-2-oxochromen-8-yl)-3-methylbut-2-enyl]3-methylbut-2-enoate (8), respectively. Meanwhile, the repellent activity against Tribolium castaneum was investigated for 13 of these isolated compounds. The results showed that the tested compounds had various levels of repellent activity against T. castaneum. Among them, compounds 1 (4(15)-eudesmene-1 beta,6 alpha-diol), 11 (isoferulic acid) and 16 (2,3-dihydroxypropyl hexadecanoate) showed fair repellent activity against T. castaneum. They might be considered as potential leading compounds for the development of natural repellents.

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