Male-specific deficits in natural reward learning in a mouse model of neurodevelopmental disorders

Mice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects

(2016) Yang Zhou et al.   NEURON

Reversal of dendritic phenotypes in 16p11.2 microduplication mouse model neurons by pharmacological targeting of a network hub

(2016) Katherine D. Blizinsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Altered mGluR5-Homer scaffolds and corticostriatal connectivity in a Shank3 complete knockout model of autism

(2016) Xiaoming Wang et al.   Nature Communications

Reciprocal Effects on Neurocognitive and Metabolic Phenotypes in Mouse Models of 16p11.2 Deletion and Duplication Syndromes

(2016) Thomas Arbogast et al.   PLoS Genetics

16p11.2 Deletion Syndrome Mice Display Sensory and Ultrasonic Vocalization Deficits During Social Interactions

(2015) Mu Yang et al.   Autism Research

Genotype-First Analysis of the 16p11.2 Deletion Defines a New Type of “Autism”

(2015) Michael H. Duyzend et al.   BIOLOGICAL PSYCHIATRY

The 16p11.2 Deletion Mouse Model of Autism Exhibits Altered Cortical Progenitor Proliferation and Brain Cytoarchitecture Linked to the ERK MAPK Pathway

(2015) J. Pucilowska et al.   JOURNAL OF NEUROSCIENCE

Dysregulation and restoration of translational homeostasis in fragile X syndrome

(2015) Joel D. Richter et al.   NATURE REVIEWS NEUROSCIENCE

Single-Cell mRNA Profiling Reveals Cell-Type-Specific Expression of Neurexin Isoforms

(2015) Marc V. Fuccillo et al.   NEURON

Understanding autism in the light of sex/gender

(2015) Meng-Chuan Lai et al.   Molecular Autism

Convergence of Genes and Cellular Pathways Dysregulated in Autism Spectrum Disorders

(2014) Dalila Pinto et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A Higher Mutational Burden in Females Supports a “Female Protective Model” in Neurodevelopmental Disorders

(2014) Sébastien Jacquemont et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Autism-Associated Neuroligin-3 Mutations Commonly Impair Striatal Circuits to Boost Repetitive Behaviors

(2014) Patrick E. Rothwell et al.   CELL

The Acquisition of Goal-Directed Actions Generates Opposing Plasticity in Direct and Indirect Pathways in Dorsomedial Striatum

(2014) Q. Shan et al.   JOURNAL OF NEUROSCIENCE

The 16p11.2 locus modulates brain structures common to autism, schizophrenia and obesity

(2014) A M Maillard et al.   MOLECULAR PSYCHIATRY

Direct and indirect pathways of basal ganglia: a critical reappraisal

(2014) Paolo Calabresi et al.   NATURE NEUROSCIENCE

Dissociable Deficits of Executive Function Caused by Gestational Adversity are Linked to Specific Transcriptional Changes in the Prefrontal Cortex

(2014) Nicola M Grissom et al.   NEUROPSYCHOPHARMACOLOGY

Distinct dopaminergic control of the direct and indirect pathways in reward-based and avoidance learning behaviors

(2014) S. Nakanishi et al.   NEUROSCIENCE

Regulation of Tyrosine Phosphatase STEP61 by Protein Kinase A during Motor Skill Learning in Mice

(2014) Laure Chagniel et al.   PLoS One

Autism as a disorder of prediction

(2014) Pawan Sinha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Behavioral Abnormalities and Circuit Defects in the Basal Ganglia of a Mouse Model of 16p11.2 Deletion Syndrome

(2014) Thomas Portmann et al.   Cell Reports

Changes in the Development of Striatum Are Involved in Repetitive Behavior in Autism

(2013) Marieke Langen et al.   BIOLOGICAL PSYCHIATRY

CNVs conferring risk of autism or schizophrenia affect cognition in controls

(2013) Hreinn Stefansson et al.   NATURE

Concurrent activation of striatal direct and indirect pathways during action initiation

(2013) Guohong Cui et al.   NATURE

Social reward requires coordinated activity of nucleus accumbens oxytocin and serotonin

(2013) Gül Dölen et al.   NATURE

Mismatch of structural and functional tonotopy for natural sounds in the auditory midbrain

(2013) C.V. Portfors et al.   NEUROSCIENCE

Examining and interpreting the female protective effect against autistic behavior

(2013) E. B. Robinson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Causative Link Between Inner Ear Defects and Long-Term Striatal Dysfunction

(2013) M. W. Antoine et al.   SCIENCE

The role of the striatum in social behavior

(2013) Raymundo Báez-Mendoza et al.   Frontiers in Neuroscience

Sex Differences in Molecular and Cellular Substrates of Stress

(2012) Debra A. Bangasser et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Operant behavior to obtain palatable food modifies ERK activity in the brain reward circuit

(2012) Thomas Guegan et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Activation of the extracellular signal-regulated kinase pathway contributes to the behavioral deficit of fragile x-syndrome

(2012) Xinglong Wang et al.   JOURNAL OF NEUROCHEMISTRY

Social ‘wanting’ dysfunction in autism: neurobiological underpinnings and treatment implications

(2012) Gregor Kohls et al.   Journal of Neurodevelopmental Disorders

Striatal Indirect Pathway Contributes to Selection Accuracy of Learned Motor Actions

(2012) K. Nishizawa et al.   JOURNAL OF NEUROSCIENCE

Disrupted ERK Signaling during Cortical Development Leads to Abnormal Progenitor Proliferation, Neuronal and Network Excitability and Behavior, Modeling Human Neuro-Cardio-Facial-Cutaneous and Related Syndromes

(2012) J. Pucilowska et al.   JOURNAL OF NEUROSCIENCE

Distinct roles for direct and indirect pathway striatal neurons in reinforcement

(2012) Alexxai V Kravitz et al.   NATURE NEUROSCIENCE

The Mysterious Motivational Functions of Mesolimbic Dopamine

(2012) John D. Salamone et al.   NEURON

Dopamine D1-Like and D2-Like Receptors in the Dorsal Striatum Control Different Aspects of Attentional Performance in the Five-Choice Serial Reaction Time Task Under a Condition of Increased Activity of Corticostriatal Inputs

(2012) Laura Agnoli et al.   NEUROPSYCHOPHARMACOLOGY

Reward system dysfunction in autism spectrum disorders

(2012) Gregor Kohls et al.   Social Cognitive and Affective Neuroscience

Emergence of context-associated GluR1 and ERK phosphorylation in the nucleus accumbens core during withdrawal from cocaine self-administration

(2011) Scott Edwards et al.   ADDICTION BIOLOGY

Aberrant Striatal Functional Connectivity in Children with Autism

(2011) Adriana Di Martino et al.   BIOLOGICAL PSYCHIATRY

Brain structure anomalies in autism spectrum disorder-a meta-analysis of VBM studies using anatomic likelihood estimation

(2011) Thomas Nickl-Jockschat et al.   HUMAN BRAIN MAPPING

Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

(2011) João Peça et al.   NATURE

Metabotropic glutamate receptor-dependent long-term depression is impaired due to elevated ERK signaling in the ΔRG mouse model of tuberous sclerosis complex

(2011) Itzamarie Chévere-Torres et al.   NEUROBIOLOGY OF DISEASE

Atypical neural networks for social orienting in autism spectrum disorders

(2011) Deanna J. Greene et al.   NEUROIMAGE

The PDE10A inhibitor, papaverine, differentially activates ERK in male and female rat striatal slices

(2011) Yu-Tien Hsu et al.   NEUROPHARMACOLOGY

Cognitive dysfunction and prefrontal synaptic abnormalities in a mouse model of fragile X syndrome

(2011) D. D. Krueger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dosage-dependent phenotypes in models of 16p11.2 lesions found in autism

(2011) G. Horev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Contributions of ERK signaling in the striatum to instrumental learning and performance

(2010) Michael W. Shiflett et al.   BEHAVIOURAL BRAIN RESEARCH

Sex differences in β-amyloid accumulation in 3xTg-AD mice: Role of neonatal sex steroid hormone exposure

(2010) Jenna C. Carroll et al.   BRAIN RESEARCH

Maternal High-Fat Diet Alters Methylation and Gene Expression of Dopamine and Opioid-Related Genes

(2010) Zivjena Vucetic et al.   ENDOCRINOLOGY

Acquisition and Performance of Goal-Directed Instrumental Actions Depends on ERK Signaling in Distinct Regions of Dorsal Striatum in Rats

(2010) M. W. Shiflett et al.   JOURNAL OF NEUROSCIENCE

Sex differences in corticotropin-releasing factor signaling and trafficking

(2010) D A Bangasser et al.   MOLECULAR PSYCHIATRY

Towards a molecular understanding of sex differences in memory formation

(2010) Keiko Mizuno et al.   TRENDS IN NEUROSCIENCES

The genetic and neurobiologic compass points toward common signaling dysfunctions in autism spectrum disorders

(2009) Pat Levitt et al.   JOURNAL OF CLINICAL INVESTIGATION

MAP'ing CNS Development and Cognition: An ERKsome Process

(2009) Ivy S. Samuels et al.   NEURON

Increased operant responding for ethanol in male C57BL/6J mice: specific regulation by the ERK1/2, but not JNK, MAP kinase pathway

(2009) Sara Faccidomo et al.   PSYCHOPHARMACOLOGY

Anticipation of monetary and social reward differently activates mesolimbic brain structures in men and women

(2009) Katja N. Spreckelmeyer et al.   Social Cognitive and Affective Neuroscience

The integrative function of the basal ganglia in instrumental conditioning

(2008) Bernard W. Balleine et al.   BEHAVIOURAL BRAIN RESEARCH

Opposing Patterns of Signaling Activation in Dopamine D1 and D2 Receptor-Expressing Striatal Neurons in Response to Cocaine and Haloperidol

(2008) J. Bertran-Gonzalez et al.   JOURNAL OF NEUROSCIENCE

The application of the 5-choice serial reaction time task for the assessment of visual attentional processes and impulse control in rats

(2008) Andrea Bari et al.   Nature Protocols

Association between Microdeletion and Microduplication at 16p11.2 and Autism

(2008) Lauren A. Weiss et al.   NEW ENGLAND JOURNAL OF MEDICINE