Endotracheal tube-induced sore throat pain and inflammation is coupled to the release of mitochondrial DNA

Neutrophil elastase induces inflammation and pain in mouse knee joints via activation of proteinase-activated receptor-2

(2015) Milind M Muley et al.   BRITISH JOURNAL OF PHARMACOLOGY

Neutrophil Elastase Activates Protease-activated Receptor-2 (PAR2) and Transient Receptor Potential Vanilloid 4 (TRPV4) to Cause Inflammation and Pain

(2015) Peishen Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Circulating TNF and mitochondrial DNA are major determinants of neutrophil phenotype in the advanced-age, frail elderly

(2015) Chris P. Verschoor et al.   MOLECULAR IMMUNOLOGY

The matrikine N- -PGP couples extracellular matrix fragmentation to endothelial permeability

(2015) C. S. Hahn et al.   Science Advances

Mitochondrial DNA Released by Trauma Induces Neutrophil Extracellular Traps

(2015) Kiyoshi Itagaki et al.   PLoS One

Mitochondrial DNA induces inflammation and increases TLR9/NF-κB expression in lung tissue

(2014) JIAN-ZHENG ZHANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Innate Immunity Mediating Inflammation Secondary to Endotracheal Intubation

(2013) Carlos A. Puyo et al.   ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY

Pattern recognition receptor function in neutrophils

(2013) Christina J. Thomas et al.   TRENDS IN IMMUNOLOGY

Neutrophil Function: From Mechanisms to Disease

(2012) Borko Amulic et al.   Annual Review of Immunology

Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis

(2012) Kenichi Shimada et al.   IMMUNITY

CD66b overexpression and homotypic aggregation of human peripheral blood neutrophils after activation by a gram-positive stimulus

(2012) Thomas Schmidt et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure

(2012) Takafumi Oka et al.   NATURE

Roles of reactive oxygen and nitrogen species in pain

(2011) Daniela Salvemini et al.   FREE RADICAL BIOLOGY AND MEDICINE

Bacterial DNA Induces Pulmonary Damage Via TLR-9 Through Cross-talk With Neutrophils

(2011) Kiyoshi Itagaki et al.   SHOCK

Functional heterogeneity and differential priming of circulating neutrophils in human experimental endotoxemia

(2010) Janesh Pillay et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Circulating mitochondrial DAMPs cause inflammatory responses to injury

(2010) Qin Zhang et al.   NATURE

MITOCHONDRIAL DNA IS RELEASED BY SHOCK AND ACTIVATES NEUTROPHILS VIA P38 MAP KINASE

(2010) Qin Zhang et al.   SHOCK

Early Biochemical Markers of Inflammation in a Swine Model of Endotracheal Intubation

(2009) Carlos A. Puyo et al.   ANESTHESIOLOGY

Role of interleukin-1β during pain and inflammation

(2009) Ke Ren et al.   BRAIN RESEARCH REVIEWS

Viable neutrophils release mitochondrial DNA to form neutrophil extracellular traps

(2009) S Yousefi et al.   CELL DEATH AND DIFFERENTIATION

Bacterial DNA Activates Endothelial Cells and Promotes Neutrophil Adherence through TLR9 Signaling

(2009) D. El Kebir et al.   JOURNAL OF IMMUNOLOGY

Human neutrophils switch to an activated phenotype after homing to the lung irrespective of inflammatory disease

(2008) E. Fortunati et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Synthetic oligonucleotides as modulators of inflammation

(2008) Dennis Klinman et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Nociceptors Are Interleukin-1  Sensors

(2008) A. M. Binshtok et al.   JOURNAL OF NEUROSCIENCE