Article
Chemistry, Multidisciplinary
Chrysoula (Chrysa) Voidarou, Maria Antoniadou, Georgios Rozos, Athanasios Alexopoulos, Elpida Giorgi, Athina Tzora, Ioannis Skoufos, Theodoros Varzakas, Eugenia Bezirtzoglou
Summary: Greek honeys, especially citrus honey and oregano and sage honey, showed better antibacterial activity than manuka honey against all tested bacteria. The enhanced antibacterial effect of the honeys when diluted in artificial saliva compared to distilled water was observed.
APPLIED SCIENCES-BASEL
(2021)
Article
Immunology
Shota Mayumi, Masae Kuboniwa, Akito Sakanaka, Ei Hashino, Asuka Ishikawa, Yura Ijima, Atsuo Amano
Summary: Recent studies have shown phenotypic and metabolic heterogeneity in related species including Streptococcus oralis, Streptococcus mutans, and Streptococcus gordonii. D-tagatose was found to be abundant in the saliva of individuals with good oral hygiene, and it selectively inhibited the growth of oral pathogens S. mutans and S. gordonii while minimally affecting the oral commensal S. oralis. This suggests the potential use of D-tagatose as an oral prebiotic for manipulating the metabolism of targeted oral streptococci.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Article
Engineering, Biomedical
Anjali Raval, Naveen S. Yadav, Shweta Narwani, Kirti Somkuwar, Varsha Verma, Hussain Almubarak, Saeed M. Alqahtani, Robina Tasleem, Alexander Maniangat Luke, Sam Thomas Kuriadom, Mohmed Isaqali Karobari
Summary: This in vitro study examined the effects of antibacterial surface treatment on titanium discs to prevent peri-implant infections. Hexagonal boron nitride nanosheets were coated onto titanium discs using the spin coating method. Two groups of titanium discs, one with the coating and one without, were tested against Streptococcus mutans and Fusobacterium nucleatum. The results showed that the coated discs had a statistically significant increase in bactericidal action against S. mutans compared to the uncoated discs.
JOURNAL OF FUNCTIONAL BIOMATERIALS
(2023)
Article
Multidisciplinary Sciences
B. A. Garcia, N. C. Acosta, S. L. Tomar, L. F. W. Roesch, J. A. Lemos, L. R. F. Mugayar, J. Abranches
Summary: The study found that Streptococcus mutans carrying collagen-binding proteins and Candida albicans are closely related to the recurrence of early childhood caries, particularly strongly associated with caries recurrence. Children in the recurrence group infected with Cbp(+)S. mutans had a heavier burden of Candida spp. and Mutans streptococci in dentin, while Streptococcus parasanguinis was overrepresented in the salivary microbiome of the caries recurrence group.
SCIENTIFIC REPORTS
(2021)
Article
Microbiology
Chiau-Jing Jung, Chih-Chieh Hsu, Jeng-Wei Chen, Hung-Wei Cheng, Chang-Tsu Yuan, Yu-Min Kuo, Ron-Bin Hsu, Jean-San Chia
Summary: The LiaR-regulated PCP protein in Streptococcus mutans plays a crucial role in bacterial biofilm formation and platelet adhesion. It is well-preserved among pathogenic streptococci and controls biofilm formation in vivo, suggesting its importance in colonization for S. mutans and possibly other pathogenic streptococci.
Article
Biochemistry & Molecular Biology
Nina M. van Sorge, Daniel A. Bonsor, Liwen Deng, Erik Lindahl, Verena Schmitt, Mykola Lyndin, Alexej Schmidt, Olof R. Nilsson, Jaime Brizuela, Elena Boero, Eric J. Sundberg, Jos A. G. van Strijp, Kelly S. Doran, Bernhard B. Singer, Gunnar Lindahl, Alex J. McCarthy
Summary: Streptococcus agalactiae, also known as group B Streptococcus (GBS), is a major cause of neonatal sepsis in humans. In a recent study, it was found that the surface-expressed beta protein of GBS binds to human CEACAM1 and CEACAM5 receptors, with the crystal structure revealing a novel IgI3 fold. This discovery suggests a potentially widely applicable mechanism for bacteria to target CEACAMs.
Review
Microbiology
Patricia P. Wright, Srinivas Sulugodu Ramachandra
Summary: Quorum sensing plays a crucial role in the pathogenicity and virulence of biofilms. This review focuses on the role of quorum sensing in cariogenic and periodontopathic biofilms and highlights the potential of quorum quenching as an antimicrobial tool to attenuate biofilm pathogenicity. Further research is needed to determine the clinical value of quorum sensing inhibitors against oral polymicrobial biofilms in vivo.
Article
Chemistry, Multidisciplinary
Leandro W. Figueira, Beatriz H. D. Panariello, Cristiane Y. Koga-Ito, Simone Duarte
Summary: Low exposure times of low-temperature plasma affect the viability of single- and multi-species cariogenic biofilms, showing promising potential for the development of new protocols for the control of dental caries.
APPLIED SCIENCES-BASEL
(2021)
Article
Microbiology
Elena Yarmola, Ivan P. Ishkov, Nicholas M. di Cologna, Megan Menashe, Robert L. Whitener, Joanna R. Long, Jacqueline Abranches, Stephen J. Hagen, L. Jeannine Brady
Summary: The number of bacterial species utilizing amyloid aggregation in biofilms is increasing. This study shows that amyloid formation reduces the activity of the Streptococcus mutans adhesin and is mainly found in the nonadherent fraction of biofilms. Understanding when and where S. mutans produces amyloid will help in developing therapeutic strategies for controlling tooth decay and other biofilm-related diseases.
MICROBIOLOGY SPECTRUM
(2022)
Article
Microbiology
So-Young Ham, Han-Shin Kim, Eunji Cha, Taehyeung Lim, Youngjoo Byun, Hee-Deung Park
Summary: Raffinose, a natural oligosaccharide, strongly inhibits biofilm formation and GTF-related gene expression in Streptococcus mutans, making it a potential antibiofilm agent for oral supplies and dental materials to prevent dental caries.
MICROBIOLOGY SPECTRUM
(2022)
Article
Infectious Diseases
Lucia Martinez-Lamas, Eliane Garcia-Mato, Anniris Rincon-Quintero, Berta Rivas-Mundina, Pedro Diz-Dios, Maximiliano Alvarez-Fernandez
Summary: This study assessed the potential mechanisms by which S. downii exerts its inhibitory effect on S. mutans and found that the main mechanism is the production of bacteriocins.
Article
Infectious Diseases
Camilla Andersen, Thomas Greve, Kasper Basse Reinholdt, Ann Marlene Gram Kjaerulff, Nichlas Udholm, Vesal Khalid, Adnan Madzak, Christophe Duez, Henrik Munch, Soren Pauli, Christian Sander Danstrup, Niels Krintel Petersen, Tejs Ehlers Klug
Summary: Microbiological analysis of patients with acute tonsillitis (AT) revealed the significance of Streptococcus pyogenes, Fusobacterium necrophorum, and Streptococcus dysgalactiae as pathogens in severe AT with or without peritonsillar phlegmon (PP). In addition, infections were associated with reduced diversity of the microbiota.
BMC INFECTIOUS DISEASES
(2023)
Article
Agriculture, Multidisciplinary
Ji-Eun Lee, Hee Yeon Cho, Jae Hoon Lee, Dong Uk Ahn, Kee-Tae Kim, Hyun-Dong Paik
Summary: This study investigated the inhibitory effects of ovomucoid, a protein found in egg white, on the biofilm formation of Streptococcus mutans, the primary pathogen associated with tooth decay. The results showed that ovomucoid inhibited biofilm formation, reduced bacterial adhesion and aggregation, and lowered the metabolic activity of bacteria in the biofilm. In addition, ovomucoid decreased the synthesis of water-insoluble EPS by S. mutans. Therefore, ovomucoid has the potential to be used as an anti-biofilm agent for the treatment of dental caries.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Article
Dentistry, Oral Surgery & Medicine
S. X. Wan, J. Tian, Y. Liu, A. Dhall, H. Koo, G. Hwang
Summary: The study revealed differences in binding forces between S. gordonii and S. mutans with Candida albicans, with the latter exhibiting significantly enhanced binding forces when the fungal surface is coated with extracellular glucans. This enhanced binding affinity led to the formation of larger structures during early biofilm initiation and ultimately resulted in the dominance of S. mutans in the 3-species biofilm model under cariogenic conditions.
JOURNAL OF DENTAL RESEARCH
(2021)
Review
Biochemistry & Molecular Biology
Virag Rona, Bulcsu Bencze, Kata Kelemen, Daniel Vegh, Reka Toth, Tamas Koi, Peter Hegyi, Gabor Varga, Noemi Katinka Rozsa, Zoltan Geczi
Summary: This study conducted a meta-analysis and systematic review to investigate the efficacy of chitosan-containing chewing gums and their inhibitory effects on Streptococcus mutans. The results showed that chitosan reduced the number of bacteria, but further studies are needed.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Medicinal
Yanfei Cui, Jing Fan, Wenbo Shi, Zuozhi Zhou
Summary: This study elucidated the crucial role of circ_0001667 in breast cancer, affecting tumor cell proliferation, migration, invasion, and chemoresistance by regulating the expression of miR-4458 and NCOA3.
DRUG DEVELOPMENT RESEARCH
(2022)
Article
Engineering, Electrical & Electronic
Chenglin Zhang, Qunfei Zhang, Wentao Shi, Weidong Wang, Jiajie Xu, Feifei Pang
Summary: The study proposes a recursive scheme relying on mobile bistatic sonar to estimate target location and clock bias accurately by acquiring measurement information at multiple time steps. Orthogonal transformation ensures computational efficiency and numerical reliability, while the CRLB is derived as a lower bound on estimating errors under Gaussian noise.
IET RADAR SONAR AND NAVIGATION
(2022)
Article
Engineering, Mechanical
Wenbo Shi, Zhousuo Zhang
Summary: This study presents a new contact characteristic parameters model for bolted joint interfaces, which overcomes the shortcomings of homogeneous distributions of contact stiffness and damping in previous models. By transforming the contact pressure distribution into normal contact load distribution, it is found that the interfacial contact stiffness and damping exhibit significant inhomogeneous distributions.
TRIBOLOGY INTERNATIONAL
(2022)
Article
Chemistry, Physical
Bing Zhang, Heli Tang, Jinyu Chen, Bing Zhang, Yu Shen, Wenxin Shi
Summary: Understanding the effect of cations on membrane fouling is important, with higher ionic strength leading to increased membrane fouling and decreased flux recovery rate. Ca2+ was found to be more effective than Na+ in mitigating membrane fouling.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Dentistry, Oral Surgery & Medicine
Fang Yang, Marcia Dinis, Farnoosh Haghighi, Xuesong He, Wenyuan Shi, Nini Chaichanasakul Tran
Summary: This pilot investigation aimed to study the colonization of Candida albicans (Ca) and Streptococcus mutans (Sm) in adolescents undergoing fixed orthodontic therapy. The study found higher levels of Ca in saliva and occlusal plaque in the FOA group, while the control group had higher levels of Sm. Additionally, a disruption in the relationship between Ca and Sm was observed in the FOA group, indicating that the presence of FOAs disturbs the colonization of these pathogens in the oral cavity.
JOURNAL OF DENTAL SCIENCES
(2022)
Article
Engineering, Environmental
Chuang Wang, Jinying Du, Zhijie Liang, Jialiang Liang, Zhiwei Zhao, Fuyi Cui, Wenxin Shi
Summary: The study investigated the removal efficiency and mechanism of fluoroquinolones using the VUV/Fe2+/PMS process, showing excellent performance at wide initial pH range. The degradation pathways of fluoroquinolones and main inorganic byproducts were thoroughly studied in this synergistic activation process.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Chemistry, Physical
Haoyue Zhang, Guangwei She, Jing Xu, Shengyang Li, Yun Liu, Jun Luo, Wensheng Shi
Summary: In this study, a Ptx(x=2,3)Si/PtSi/p-Si photocathode was designed and fabricated to improve the photovoltage and enhance the hydrogen evolution reaction kinetics for efficient H-2 generation via PEC. The use of dopant segregation elevated the Schottky barrier height, leading to a high photovoltage, while in situ formation of a high catalytic activity Ptx(x=2,3)Si layer on the photocathode significantly enhanced the HER kinetics. The photocathode achieved a favorable onset potential for HER and a high saturated photocurrent density, with a maximum ABPE of 5.8% and excellent stability in long-term PEC H-2 generation testing.
JOURNAL OF MATERIALS CHEMISTRY A
(2022)
Article
Engineering, Electrical & Electronic
Wentao Shi, Chen Dong, Zhou Lin, Bai Ke, Jin Yong
Summary: In this paper, a novel sensor selection method considering uncertainty disturbance is proposed for effective target detection in a multisensor cooperative detection network. The method models the sensor selection problem as a binary form optimization problem and quantifies the factors affecting the selection scheme. The proposed method ensures the minimum number of sensors and improves the accuracy of state estimation, as evidenced by simulation results.
JOURNAL OF SENSORS
(2022)
Article
Chemistry, Analytical
Tyler Chozinski, B. Scott Ferguson, William Fisher, Shencheng Ge, Qiang Gong, Hui Kang, John McDermott, Alexander Scott, Wentao Shi, Jeremiah J. Trausch, Thorsten Verch, Matthew Vukovich, Jinpeng Wang, J. Emma Wu, Qin Yang
Summary: This study aims to develop a portable device for affinity assays of viral particles in viral vaccines by combining aptamers, microfluidic devices, and electrochemical detection. By generating and characterizing aptamers and designing/fabricating electrochemical microfluidic devices, CMV concentrations were successfully measured. This work represents a critical first step towards developing simple, affordable, and robust affinity assays for global deployment.
ANALYTICAL CHEMISTRY
(2022)
Article
Multidisciplinary Sciences
Yan Guo, Qixin Zhou, Jun Nan, Wenxin Shi, Fuyi Cui, Yongfa Zhu
Summary: This study synthesized perylenetetracarboxylic acid nanosheets with a thickness of approximately 1.5 nm and demonstrated their activity as highly efficient hydrogen evolution photocatalysts. The introduction of carboxyl groups increased the internal electric fields, promoting charge-carrier separation, and weakened charge-carrier recombination by migrating photogenerated electrons and holes to the edge and plane, respectively. Furthermore, the reduction potential and hydrophilic sites of perylenetetracarboxylic acid were enhanced. This work provides a strategy for designing future efficient photocatalysts.
NATURE COMMUNICATIONS
(2022)
Article
Cell & Tissue Engineering
Wentao Shi, Zhe Wang, Lu Bian, Yiqing Wu, Mei HuiYa, Yanjun Zhou, Zhijian Zhang, Qing Wang, Peng Zhao, Xiaojie Lu
Summary: This study found that periodic heat stress promotes the differentiation of EMSCs into osteoblasts, and YAP plays a key role in regulating the TG2 response.
STEM CELLS INTERNATIONAL
(2022)
Article
Pharmacology & Pharmacy
Wentao Shi, Manali Singha, Gopal Srivastava, Limeng Pu, J. Ramanujam, Michal Brylinski
Summary: Computational modeling is crucial in modern drug discovery, particularly in predicting binding molecules. Pocket2Drug is a promising computational approach that uses data mining and machine learning to predict binding molecules for a given ligand binding site.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Fangfang Wu, Yuchao Chen, Yulong Chen, Ruilian Yin, Yancong Feng, Dong Zheng, Xilian Xu, Wenhui Shi, Wenxian Liu, Xiehong Cao
Summary: Optimization of electrolyte composition is a practical way to improve the performance of aqueous zinc-ion batteries (ZIBs). In this study, a mixture electrolyte containing 10 vol% of N,N-Dimethylacetamide (DMA) and ZnSO4 was used to enhance the reversibility of Zn plating/stripping. It was found that DMA has the ability to reconstruct the solvation structure of Zn2+ and inhibit dendrite growth on Zn anode.
Article
Cell & Tissue Engineering
Qian Li, Jiahua Zheng, Zhongkang Li, Yanlai Xiao, Mingle Zhang, Wenxin Shi, He Gao, Xianghua Huang, Jingkun Zhang
Summary: The 3D-bioprinted engineering ovary, combining drug-free IVA and ADSCs, has the potential to ameliorate impaired ovarian function in rats with POI by promoting angiogenesis and restoration of hormone levels.
STEM CELL RESEARCH & THERAPY
(2022)
Article
Business, Finance
Wen Shi, Xiaogang Bi
Summary: This research examines the impact of Buddhism on mergers & acquisitions (M&As) performance using data from 4622 M&A transactions of Chinese public firms between 2004 and 2018. The findings provide ample evidence that acquirers located in regions with a higher intensity of Buddhism achieve better short-term and long-term performance after the merger. Furthermore, the study reveals that state ownership plays a crucial role in mitigating this effect, and the value creation is driven by higher deal completion rates and fewer violation cases for acquiring firms. Finally, the study addresses the issue of endogeneity, and the results remain unchanged.
ACCOUNTING AND FINANCE
(2023)