USP22 mediates the multidrug resistance of hepatocellular carcinoma via the SIRT1/AKT/MRP1 signaling pathway

The Warburg effect and drug resistance

(2016) Bhaskar Bhattacharya et al.   BRITISH JOURNAL OF PHARMACOLOGY

Personalized therapy for hepatocellular carcinoma: Where are we now?

(2016) Stephen L. Chan et al.   CANCER TREATMENT REVIEWS

MiR-138-5p promotes TNF-α-induced apoptosis in human intervertebral disc degeneration by targeting SIRT1 through PTEN/PI3K/Akt signaling

(2016) Bing Wang et al.   EXPERIMENTAL CELL RESEARCH

Histone Deacetylase SIRT1 Controls Proliferation, Circadian Rhythm, and Lipid Metabolism during Liver Regeneration in Mice

(2016) Marina Maria Bellet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear GSK3β promotes tumorigenesis by phosphorylating KDM1A and inducing its deubiquitylation by USP22

(2016) Aidong Zhou et al.   NATURE CELL BIOLOGY

Global cancer statistics, 2012

(2015) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Impact of Genetic Polymorphisms of ABCB1 (MDR1, P-Glycoprotein) on Drug Disposition and Potential Clinical Implications: Update of the Literature

(2015) Stefan Wolking et al.   CLINICAL PHARMACOKINETICS

The modulation of ABC transporter-mediated multidrug resistance in cancer: A review of the past decade

(2015) Rishil J. Kathawala et al.   DRUG RESISTANCE UPDATES

Turning Hepatic Cancer Stem Cells Inside Out – A Deeper Understanding through Multiple Perspectives

(2015) Lok-Hei Chan et al.   MOLECULES AND CELLS

Ubiquitin-specific peptidase 22 overexpression may promote cancer progression and poor prognosis in human gastric carcinoma

(2015) Yan He et al.   Translational Research

Ubiquitin-specific protease 22 is a deubiquitinase of CCNB1

(2015) Zhenghong Lin et al.   Cell Discovery

ShRNA-mediated silencing of the ubiquitin-specific protease 22 gene restrained cell progression and affected the Akt pathway in nasopharyngeal carcinoma

(2014) Ya-Jing Zhuang et al.   CANCER BIOLOGY & THERAPY

SIRT1 Positively Regulates Autophagy and Mitochondria Function in Embryonic Stem Cells Under Oxidative Stress

(2014) Xuan Ou et al.   STEM CELLS

PARP1 inhibition affects pleural mesothelioma cell viability and uncouples AKT/mTOR axis via SIRT1

(2013) Giulia Pinton et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Randomized, Multicenter, Open-Label Study of Oxaliplatin Plus Fluorouracil/Leucovorin Versus Doxorubicin As Palliative Chemotherapy in Patients With Advanced Hepatocellular Carcinoma From Asia

(2013) Shukui Qin et al.   JOURNAL OF CLINICAL ONCOLOGY

A High-Confidence Interaction Map Identifies SIRT1 as a Mediator of Acetylation of USP22 and the SAGA Coactivator Complex

(2013) S. M. Armour et al.   MOLECULAR AND CELLULAR BIOLOGY

FUT family mediates the multidrug resistance of human hepatocellular carcinoma via the PI3K/Akt signaling pathway

(2013) L Cheng et al.   Cell Death & Disease

Gemcitabine plus oxaliplatin in advanced hepatocellular carcinoma: A large multicenter AGEO study

(2012) Aziz Zaanan et al.   JOURNAL OF HEPATOLOGY

USP22 Antagonizes p53 Transcriptional Activation by Deubiquitinating Sirt1 to Suppress Cell Apoptosis and Is Required for Mouse Embryonic Development

(2012) Zhenghong Lin et al.   MOLECULAR CELL

SIRT1 Promotes Tumorigenesis and Resistance to Chemotherapy in Hepatocellular Carcinoma and its Expression Predicts Poor Prognosis

(2011) Hsieh-Cheng Chen et al.   ANNALS OF SURGICAL ONCOLOGY

USP22 Acts as an Oncogene by the Activation of BMI-1-Mediated INK4a/ARF Pathway and Akt Pathway

(2011) Yan-Long Liu et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

A Human Model of Epithelial to Mesenchymal Transition to Monitor Drug Efficacy in Hepatocellular Carcinoma Progression

(2011) F. van Zijl et al.   MOLECULAR CANCER THERAPEUTICS

The Deacetylase SIRT1 Promotes Membrane Localization and Activation of Akt and PDK1 During Tumorigenesis and Cardiac Hypertrophy

(2011) N. R. Sundaresan et al.   Science Signaling

LAPTM4B: A novel cancer-associated gene motivates multidrug resistance through efflux and activating PI3K/AKT signaling

(2010) L Li et al.   ONCOGENE

Regulation and Cellular Roles of Ubiquitin-Specific Deubiquitinating Enzymes

(2009) Francisca E. Reyes-Turcu et al.   Annual Review of Biochemistry

Gcn5 and SAGA Regulate Shelterin Protein Turnover and Telomere Maintenance

(2009) Boyko S. Atanassov et al.   MOLECULAR CELL

Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial

(2008) Ann-Lii Cheng et al.   LANCET ONCOLOGY

The Putative Cancer Stem Cell Marker USP22 Is a Subunit of the Human SAGA Complex Required for Activated Transcription and Cell-Cycle Progression

(2008) Xiao-Yong Zhang et al.   MOLECULAR CELL