Orexin A/Hypocretin Modulates Leptin Receptor-Mediated Signaling by Allosteric Modulations Mediated by the Ghrelin GHS-R1A Receptor in Hypothalamic Neurons

From Belly to Brain: Targeting the Ghrelin Receptor in Appetite and Food Intake Regulation

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Quaternary structure of a G-protein-coupled receptor heterotetramer in complex with Gi and Gs

(2016) Gemma Navarro et al.   BMC BIOLOGY

Heteroreceptor Complexes Formed by Dopamine D1, Histamine H3, and N-Methyl-D-Aspartate Glutamate Receptors as Targets to Prevent Neuronal Death in Alzheimer’s Disease

(2016) Mar Rodríguez-Ruiz et al.   MOLECULAR NEUROBIOLOGY

Orexin-Corticotropin-Releasing Factor Receptor Heteromers in the Ventral Tegmental Area as Targets for Cocaine

(2015) G. Navarro et al.   JOURNAL OF NEUROSCIENCE

Structures for G-Protein-Coupled Receptor Tetramers in Complex with G Proteins

(2015) Arnau Cordomí et al.   TRENDS IN BIOCHEMICAL SCIENCES

The G Protein-Coupled Receptor Heterodimer Network (GPCR-HetNet) and Its Hub Components

(2014) Dasiel Borroto-Escuela et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Orexin/hypocretin receptor signalling cascades

(2013) J P Kukkonen et al.   BRITISH JOURNAL OF PHARMACOLOGY

Ultrasensitive fluorescent proteins for imaging neuronal activity

(2013) Tsai-Wen Chen et al.   NATURE

The physiological role of orexin/hypocretin neurons in the regulation of sleep/wakefulness and neuroendocrine functions

(2013) Ayumu Inutsuka et al.   Frontiers in Endocrinology

Promiscuous Dimerization of the Growth Hormone Secretagogue Receptor (GHS-R1a) Attenuates Ghrelin-mediated Signaling

(2012) Harriët Schellekens et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Apo-Ghrelin Receptor Forms Heteromers with DRD2 in Hypothalamic Neurons and Is Essential for Anorexigenic Effects of DRD2 Agonism

(2012) Andras Kern et al.   NEURON

Modification of ghrelin receptor signaling by somatostatin receptor-5 regulates insulin release

(2012) S. Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heteromultimerization of Cannabinoid CB1Receptor and Orexin OX1Receptor Generates a Unique Complex in Which Both Protomers Are Regulated by Orexin A

(2011) Richard J. Ward et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutually Opposite Signal Modulation by Hypothalamic Heterodimerization of Ghrelin and Melanocortin-3 Receptors

(2011) Anne Rediger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dopamine D1-histamine H3Receptor Heteromers Provide a Selective Link to MAPK Signaling in GABAergic Neurons of the Direct Striatal Pathway

(2010) Estefanía Moreno et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of orexin-A in food motivation, reward-based feeding behavior and food-induced neuronal activation in rats

(2010) D.L. Choi et al.   NEUROSCIENCE

Marked changes in signal transduction upon heteromerization of dopamine D1 and histamine H3 receptors

(2009) Carla Ferrada et al.   BRITISH JOURNAL OF PHARMACOLOGY

Building a new conceptual framework for receptor heteromers

(2009) Sergi Ferré et al.   Nature Chemical Biology

Detection of heteromerization of more than two proteins by sequential BRET-FRET

(2008) Paulina Carriba et al.   NATURE METHODS

Leptin transiently antagonizes ghrelin and long-lastingly orexin in regulation of Ca2+ signaling in neuropeptide Y neurons of the arcuate nucleus

(2008) Daisuke Kohno et al.   WORLD JOURNAL OF GASTROENTEROLOGY