Drug-Induced HSP90 Inhibition Alleviates Pain in Monoarthritic Rats and Alters the Expression of New Putative Pain Players at the DRG

Molecular structure and function of P2X receptors

(2016) Chloé Habermacher et al.   NEUROPHARMACOLOGY

HSP90 and HSP70: Implication in Inflammation Processes and Therapeutic Approaches for Myeloproliferative Neoplasms

(2015) Margaux Sevin et al.   MEDIATORS OF INFLAMMATION

Células gliais satélite de gânglios sensitivos: o seu papel na dor

(2015) Filipa Alexandra Leite Costa et al.   Revista Brasileira de Anestesiologia

Reversal of Monoarthritis-induced Affective Disorders by Diclofenac in Rats

(2014) Gisela Borges et al.   ANESTHESIOLOGY

17-Dimethylaminoethylamino-17-demethoxygeldanamycin Attenuates Inflammatory Responses in Experimental Stroke

(2014) Jia Qi et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Role of activating transcription factor 3 protein ATF3 in necrosis and apoptosis induced by 5-fluoro-2′-deoxyuridine

(2014) Akira Sato et al.   FEBS Journal

HSP90 cleavage associates with oxidized proteins accumulation after oxidative stress

(2014) Jos Pedro Castro et al.   FREE RADICAL BIOLOGY AND MEDICINE

Primary sensory neurons regulate Toll-like receptor-4-dependent activity of glial cells in dorsal root ganglia

(2014) K.-H. Tse et al.   NEUROSCIENCE

Mirror-image pain is mediated by nerve growth factor produced from tumor necrosis factor alpha-activated satellite glia after peripheral nerve injury

(2014) Chau-Fu Cheng et al.   PAIN

Satellite Glial Cells Surrounding Primary Afferent Neurons Are Activated and Proliferate during Monoarthritis in Rats: Is There a Role for ATF3?

(2014) Diana Sofia Marques Nascimento et al.   PLoS One

Involvement of the P2X7 Purinergic Receptor in Colonic Motor Dysfunction Associated with Bowel Inflammation in Rats

(2014) Luca Antonioli et al.   PLoS One

P2X7 receptor of rat dorsal root ganglia is involved in the effect of moxibustion on visceral hyperalgesia

(2014) Shuangmei Liu et al.   Purinergic Signalling

Regulation of ATP-Gated P2X Channels: From Redox Signaling to Interactions with Other Proteins

(2013) Stanko S. Stojilkovic et al.   ANTIOXIDANTS & REDOX SIGNALING

Physiological Roles and Potential Therapeutic Applications of the P2X7 Receptor in Inflammation and Pain

(2013) Luiz Alves et al.   MOLECULES

Functional up-regulation of P2X3 receptors in dorsal root ganglion in a rat model of bone cancer pain

(2012) J.X. Wu et al.   EUROPEAN JOURNAL OF PAIN

P2X3-mediated peripheral sensitization of neuropathic pain in resiniferatoxin-induced neuropathy

(2012) Yu-Lin Hsieh et al.   EXPERIMENTAL NEUROLOGY

Geldanamycin and its derivatives as Hsp90 inhibitors

(2012) Magdalena Gorska   Frontiers in Bioscience-Landmark

The novel HSP90 inhibitor, PU-H71, suppresses glial cell activation but weakly affects clinical signs of EAE

(2012) Lucia Lisi et al.   JOURNAL OF NEUROIMMUNOLOGY

P2X7 Receptors in Satellite Glial Cells Mediate High Functional Expression of P2X3 Receptors in Immature Dorsal Root Ganglion Neurons

(2012) Yong Chen et al.   Molecular Pain

Neuronal P2X3 receptor activation is essential to the hyperalgesia induced by prostaglandins and sympathomimetic amines released during inflammation

(2012) F.C. Prado et al.   NEUROPHARMACOLOGY

Hsp90 Is Cleaved by Reactive Oxygen Species at a Highly Conserved N-Terminal Amino Acid Motif

(2012) Raphaël Beck et al.   PLoS One

A potential therapeutic role for P2X7 receptor (P2X7R) antagonists in the treatment of inflammatory diseases

(2011) Nishkantha Arulkumaran et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Ret-Dependent and Ret-Independent Mechanisms of Gfl-Induced Sensitization

(2011) Brian S Schmutzler et al.   Molecular Pain

Heat shock transcription factor 1 as a therapeutic target in neurodegenerative diseases

(2011) Daniel W. Neef et al.   NATURE REVIEWS DRUG DISCOVERY

Neuronal Injury Marker ATF-3 Is Induced in Primary Afferent Neurons of Monoarthritic Rats

(2011) Diana Nascimento et al.   NEUROSIGNALS

Inhibiting Heat-Shock Protein 90 Reverses Sensory Hypoalgesia in Diabetic Mice

(2010) Michael J Urban et al.   ASN Neuro

Activating transcription factor-3 (ATF3) functions as a tumor suppressor in colon cancer and is up-regulated upon heat-shock protein 90 (Hsp90) inhibition

(2010) Christina Hackl et al.   BMC CANCER

Heat shock protein 90 inhibitors attenuate inflammatory responses in atherosclerosis

(2010) Julio Madrigal-Matute et al.   CARDIOVASCULAR RESEARCH

EC144, a Synthetic Inhibitor of Heat Shock Protein 90, Blocks Innate and Adaptive Immune Responses in Models of Inflammation and Autoimmunity

(2010) T. J. Yun et al.   JOURNAL OF IMMUNOLOGY

Can satellite glial cells be therapeutic targets for pain control?

(2010) Luc Jasmin et al.   Neuron Glia Biology

Nociceptive behaviour upon modulation of mu-opioid receptors in the ventrobasal complex of the thalamus of rats

(2010) Daniel Humberto Pozza et al.   PAIN

The Role of Glia and the Immune System in the Development and Maintenance of Neuropathic Pain

(2010) Ricardo Vallejo et al.   Pain Practice

Activating Transcription Factor 3 Constitutes a Negative Feedback Mechanism That Attenuates Saturated Fatty Acid/Toll-Like Receptor 4 Signaling and Macrophage Activation in Obese Adipose Tissue

(2009) Takayoshi Suganami et al.   CIRCULATION RESEARCH

Evidence for a role of heat shock protein-90 in toll like receptor 4 mediated pain enhancement in rats

(2009) M.R. Hutchinson et al.   NEUROSCIENCE

Small molecule inhibitors of Hsp90 potently affect inflammatory disease pathways and exhibit activity in models of rheumatoid arthritis

(2008) John W. Rice et al.   ARTHRITIS AND RHEUMATISM

Activating transcription factor 3 is a negative regulator of allergic pulmonary inflammation

(2008) Mark Gilchrist et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Pathological and protective roles of glia in chronic pain

(2008) Erin D. Milligan et al.   NATURE REVIEWS NEUROSCIENCE

Activation of P2X7 receptors in glial satellite cells reduces pain through downregulation of P2X3 receptors in nociceptive neurons

(2008) Y. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA